At a Glance
- Tasks: Lead innovative research in functional genomics and apply CRISPR technologies to cancer drug discovery.
- Company: Join Cancer Research Horizons at the forefront of cancer research and technology development.
- Benefits: Generous benefits package, career development opportunities, and a supportive work environment.
- Other info: Dynamic lab-based role with excellent career growth potential in a collaborative team.
- Why this job: Make a real impact in cancer treatment while working with cutting-edge technologies.
- Qualifications: PhD in relevant field, experience with CRISPR, and strong communication skills.
The predicted salary is between 60000 - 80000 £ per year.
We have an exciting opportunity at Cancer Research Horizons for a skilled Principal Scientist to join the Joint AstraZeneca-Cancer Research Horizons Functional Genomics Centre based in Cambridge. This role offers the unique opportunity to be part of an exciting team, operating at the forefront of research and technology development, gaining experience across the breadth of CRISPR technologies whilst it is being applied to clinically actionable programs. Working in a diverse, dynamic, and cutting-edge scientific environment, this laboratory-based role will give you the opportunity to apply your molecular and cell biology and drug discovery expertise to build new capabilities and support our functional genomic screening efforts.
Cancer Research Horizons (CRH) is CRUK's internal translation engine. CRUK's established drug discovery teams operate under one organisation and leadership team. Our unique combination of cancer biology expertise and access to CRUK's world-class academic network, coupled with cutting edge technology platforms and clinical expertise enables us to bring new treatments to patients faster and tackle the biggest challenges in discovering cancer drugs by seeking out more radical ideas and embracing risk in our bid to achieve success.
Key Responsibilities:- A PhD in a relevant scientific discipline (or equivalent experience), preferably with up to 5 years of postdoctoral experience.
- Experience in a biotech or pharmaceutical setting is considered a plus.
- Prior hands-on experience with CRISPR screening modalities, particularly for target discovery.
- Exposure to advanced techniques (e.g., base editing, CRISPR activation, Perturb-seq, or combinatorial screening) is a strong advantage.
- Experience working with complex, disease-relevant cellular models (e.g., 3D/organoid cultures, primary immune cells) or in vivo systems.
- The ability to leverage bioinformatics datasets and genome/proteome-wide technologies, applying rigorous statistical thinking to large-scale biological data.
- Excellent communication skills, a collaborative mindset, and the ability to work effectively across cross-functional matrix teams.
We create a working environment that supports your wellbeing and provide a generous benefits package, a wide range of career and personal development opportunities and high-quality tools. Our policies and processes enable you to improve your work-life balance, take positive steps in your career and achieve your personal wellbeing goals.
Principal Scientist (Functional Genomics) employer: Cancer Research UK
Cancer Research UK is an exceptional employer, offering a dynamic work environment in Stratford, London, where you can make a meaningful impact on health partnerships. With a strong emphasis on employee well-being, we provide flexible working arrangements and a comprehensive benefits package that supports a healthy work/life balance, alongside ample opportunities for professional growth and development within the organisation.
StudySmarter Expert Advice🤫
We think this is how you could land Principal Scientist (Functional Genomics)
✨Get Involved in Local Research Communities
Tap into local biotechnology meetups and research forums. These are great places to mingle with industry professionals, share your passion, and even discover unadvertised job openings. It's all about getting your face known in the field!
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If you're a recent grad, don’t underestimate the power of your university’s alumni network! Reach out to alumni working in biotechnology to gather tips about job openings at companies like Cancer Research UK. You'd be surprised how willing people are to help out a fellow grad!
✨Show Off Your Projects
Curate a portfolio showcasing any research projects or internships you've completed in biotechnology. This tangible evidence of your skills can really impress employers when you chat with them at networking events or interviews. It's about making that killer first impression!
✨Stay Up-to-Date with Industry Trends
Biotech is a fast-paced field, so keeping yourself updated with the latest advancements is crucial. Attend industry conferences, webinars, or workshops to broaden your knowledge and meet potential employers. Plus, it’ll give you fantastic talking points for your interviews at places like Cancer Research UK!
We think you need these skills to ace Principal Scientist (Functional Genomics)
Some tips for your application 🫡
Show Off Your Lab Skills:In the biotechnology field, it's super important to highlight your lab experience in your CV. Be sure to mention specific techniques or instruments you've mastered (think PCR, gel electrophoresis, etc.) and any relevant projects you've worked on. This will show Cancer Research UK that you have the hands-on skills they need.
Tailor Your Technical Skills:Make sure to emphasise your technical skills, especially those relevant to the biotechnology sector. Include any software tools or programming languages you've used, like R or Python for data analysis, which could be key for this role at Cancer Research UK.
Craft a Compelling Cover Letter:Since this is a full-time role, your cover letter should reflect not only your passion for biotechnology but also your long-term career ambitions. Share why you're excited about the work that Cancer Research UK does and how you envision contributing to their goals. This shows that you’re not just looking for any job, but you're genuinely invested in this opportunity.
Include Your Papers and Projects:If you've published any papers or contributed to significant projects, mention them! These documents can boost your application and provide tangible evidence of your expertise in the biotechnology field. Don’t forget to link to any relevant publications or project summaries—this can set you apart from other candidates.
How to prepare for a job interview at Cancer Research UK
✨Brush Up on Lab Techniques
Since you're eyeing a full-time gig in biotechnology, make sure you're well-versed in the lab techniques relevant to the role. Be ready to talk about PCR, CRISPR, or any specific methods mentioned in the job description at Cancer Research UK. You might even be asked to demonstrate your understanding of these processes.
✨Know Your Bioinformatics Tools
Get comfortable with bioinformatics tools that are commonly used in the industry, like BLAST or Bioconductor. These are key in biotechnology, and having hands-on experience or at least familiarity can set you apart. Prepare to discuss any relevant projects you've worked on, especially if they involved data analysis or genomic research.
✨Show Your Teamwork Skills
Biotech often involves collaboration across multiple disciplines. Be ready to share stories that highlight your teamwork and communication skills, especially in research projects. Think about working with different teams at university or any internships – this is where you can show how well you fit into Cancer Research UK's culture.
✨Research Recent Biotech Innovations
Stay updated on the latest trends and breakthroughs in biotechnology. Knowing what's happening in the field can help you engage in more meaningful discussions during your interview. Bring up recent articles or advancements that excite you, especially those related to the work being done at Cancer Research UK. This shows your passion for the industry!
