At a Glance
- Tasks: Join a dynamic team to develop cutting-edge spatial technology for genetic research.
- Company: The Broad Institute, a leader in genetic research and innovation.
- Benefits: Competitive salary, comprehensive benefits, and generous paid time off.
- Other info: Collaborative environment with opportunities for professional growth and development.
- Why this job: Make a real impact in groundbreaking research with mentorship from top scientists.
- Qualifications: Bachelor's or Master's degree with relevant experience in molecular biology or biotechnology.
The predicted salary is between 65000 - 91667 £ per year.
The Broad Institute of MIT & Harvard, a world leader in genetic research, is looking for an exceptional candidate to join the Spatial Technology Platform (STP). STP utilizes cutting-edge spatial profiling methods to generate highly multiplexed and multi-modal data sets at single-cell resolution as a high-throughput scaled service at the Broad Institute. Our focus lies in highly multiplexed spatial transcriptomics alongside in situ proteomics and optical barcoding technologies for demultiplexing CRISPR perturbations.
We are seeking a highly motivated individual to join the imaging group within our team and support workflows and quality control methods as we transition spatial transcriptomics assays to scaled service operations, pilot and develop combined multimodal assays, and develop techniques to troubleshoot spatial assays at intermediate points. We value strong teamwork, clear communication, and autonomy. While the role requires independent initiative and will be highly dynamic, you'll benefit from close mentorship and guidance from our senior researchers.
KEY RESPONSIBILITIES:
- Develop and evaluate methods to assess quality of input material for spatial transcriptomics assays - RNA extraction and DV200 profiling, H&E imaging, and RNAscope profiling.
- Pilot methods to adapt spatial transcriptomics workflows for high-throughput profiling of cultured cells.
- Implement imaging-based spatial profiling methods such as 10X Xenium in combination with other assays such as RNAscope and multiplexed immunofluorescence.
- Support the platform’s self-service imaging instrumentation through user training of widefield, confocal, and light sheet microscopy.
- Attention to detail when troubleshooting and resolving issues in assays; ability to propose next steps or directions even when the path to an experimental goal is not clear.
- Support of histology needs.
- Flexibility in a rapidly changing environment.
- Document, compile, and analyze experimental data.
- Attend and present at team meetings to share results and ensure that projects support team goals.
QUALIFICATIONS:
- Bachelor’s degree with at least 5+ years of related work experience, or Master’s degree with 3+ years of experience.
- Experience in molecular biology, biochemistry, biotechnology, or a related field.
- Experience with fluorescence microscopy and imaging.
- Strong wet lab skills and experience with tissue processing (histology) are required. Experience in imaging or spatial genomics is highly desirable.
- Great teamwork skills, including the ability to engage with external collaborators.
- Highly independent and resourceful.
- Computational analysis is a plus.
The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.
Research Associate III - Spatial Technology Platform in Cambridge employer: Broad Institute
The Broad Institute is an exceptional employer, offering a dynamic work environment in Cambridge, MA, where innovation meets collaboration. As a Clinical Genomics Coordinator, you will be part of a mission-driven team dedicated to advancing precision medicine through cutting-edge genomic research, with ample opportunities for professional growth and development. Enjoy a comprehensive benefits package, a supportive work culture, and the chance to contribute to impactful projects that shape the future of healthcare.
StudySmarter Expert Advice🤫
We think this is how you could land Research Associate III - Spatial Technology Platform in Cambridge
✨Get Involved in Research Communities
Dive headfirst into the scientific research world by joining relevant communities and forums. Engage in discussions, share your insights, and even attend conferences or seminars in your field. This not only boosts your visibility but can also lead to potential job opportunities—don't forget to connect with like-minded folks!
✨Show Off Your Research Projects
Have you worked on any cool research projects? Make it easy for potential employers to see your work by creating a portfolio or a personal website. This way, when you apply for roles like the one at Broad Institute, you can point them to your projects and publications, showcasing your expertise directly.
✨Utilise Professional Networks
Networking is key in scientific research. Join professional bodies or organisations related to your field. They often have job boards and resources tailored for job seekers. Make connections with professionals who may know about openings or can give you tips on landing a full-time position.
✨Keep Your Eyes on Openings & Apply Directly
Don’t just rely on job boards! Keep an eye on the careers section of the websites of companies like Broad Institute. Apply directly through their website because sometimes they post jobs there before anywhere else. Plus, it shows your proactive approach!
We think you need these skills to ace Research Associate III - Spatial Technology Platform in Cambridge
Some tips for your application 🫡
Highlight Your Research Experience:When applying for a full-time role in scientific research, make sure to emphasise your research experience prominently in your CV. Share specific projects you’ve worked on, the methodologies you used, and any significant findings. If you’ve published papers or presented at conferences, definitely include that too – it shows you’re on it in the academic world!
Tailor Your Cover Letter to the Research Area:Your cover letter should reflect your passion for the specific area of research at Broad Institute. Mention relevant experiences that align with the organisation’s goals or projects. This shows that you’ve done your homework and are genuinely interested in the position – plus, it helps us see how you’d fit into the team dynamics.
Showcase Your Data Analysis Skills:In scientific research, data analysis skills are a big deal! Make sure to detail any relevant analytical tools or software you’re familiar with, like R, Python, or statistical packages. Employers are keen to know you can handle the data-heavy elements of the role, so add specific examples where you’ve used these skills effectively.
Discuss Your Future Research Goals:In your motivation section, it’s a great idea to talk about your future research goals and how they align with the work being done at Broad Institute. This shows that you’re not just looking for any job, but rather a chance to contribute meaningfully to the field. We love to see applicants who are forward-thinking and enthusiastic about their research journey!
How to prepare for a job interview at Broad Institute
✨Showcase Your Research Skills
In scientific research, it’s crucial to demonstrate your ability to design and conduct experiments. Come armed with examples of past projects where you've developed hypotheses, collected data, and analysed results. Be ready to discuss any specific methodologies or tools you’ve used, like PCR techniques or statistical software.
✨Prepare for Technical Questions
Expect some technical questions specific to your field. Make sure you're up to speed with recent advancements in scientific research related to the role at Broad Institute. Brush up on concepts relevant to their projects and be prepared to discuss how you would approach a specific research problem or challenge they might face.
✨Know Your Publications
If you've authored or co-authored any papers, be prepared to discuss them! Highlighting your contributions to published research can really set you apart. It shows not only your expertise but also your ability to communicate complex ideas clearly, which is key in scientific research roles.
✨Exhibit Your Team Spirit
In full-time roles, collaboration is often at the heart of scientific research. Prepare examples that show how you've successfully worked in teams, dealt with conflicts, or contributed to group projects. We want to know how you can work effectively with the team at Broad Institute to drive research projects forward.