Senior Manager, Patient Safety Scientist in Denham

Working with Us

Challenging. Meaningful. Life‑changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high‑achieving teams. Take your career farther than you thought possible.

Make Safety Your Science

At Bristol Myers Squibb, we're driven by a single mission: to discover, develop, and deliver innovative medicines that help patients prevail over serious diseases. Behind every medicine we bring to patients is a team of experts committed to keeping them safe — and we're looking for a talented pharmacovigilance professional to join that team.

The Role

As Senior Manager, Patient Safety Science, you'll be at the heart of how BMS characterises and protects the safe use of its medicines. Working closely with Medical Safety Assessment Physicians and Safety Management Teams, you'll own signal detection, lead safety data review meetings, drive risk management strategies, and ensure robust pharmacovigilance compliance across the product lifecycle — from early development through to postmarketing.

This is a high‑impact role with real autonomy, cross‑functional visibility, and the opportunity to shape benefit‑risk decisions on medicines that matter.

What You’ll Do

• Detect & manage signals – Lead quantitative signal detection, author comprehensive signal reports, and escalate issues that could impact key safety milestones.
• Drive safety surveillance – Prepare and contribute to aggregate safety documents (DSURs, PBRERs, PADERs) and respond to health authority queries.
• Support clinical development – Contribute to safety sections of protocols, investigator brochures, CSRs, and informed consent forms.
• Shape regulatory submissions – Author safety sections of MAAs, including ISS, SCS, clinical overviews, and product labelling (USPI, CCDS, SmPC).
• Lead risk management – Develop and maintain global and EU Risk Management Plans, additional Risk Minimisation Measures, and Post‑Authorisation Safety Studies.
• Champion innovation – Leverage AI, automation, and digital platforms to continuously improve safety workflows and data analysis.

What You’ll Bring

Education

Scientific degree (BS, MS, PharmD, PhD, MD, RN, or equivalent).

Experience

4–6+ years in pharmacovigilance, drug development, or the pharmaceutical industry.

Skills & Attributes

• Solid grounding in global pharmacovigilance regulations and postmarketing safety requirements.
• Strong analytical mindset with the ability to interpret complex clinical, nonclinical, and real‑world safety data.
• Excellent organisational skills with the ability to manage competing timelines without compromising quality.
• A collaborative, adaptable communicator who thrives in cross‑functional environments.
• Comfort working with emerging technologies including AI and digital safety tools.

Equal Employment Opportunity

BMS is an equal‑opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, veteran status, or any other protected characteristic. BMS considers applicants with arrest and conviction records as required by applicable laws. We will not request payments, financial information, or social security numbers during the application process.