Senior Manager, Early Clinical Development, Clinical Pharmacology Studies in Denham

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.

What if your next role could change someone's life? Not in a vague, corporate-speak kind of way. We mean genuinely, concretely, and measurably change the life of a patient who is waiting for a treatment that does not yet exist. This is your invitation to shape medicines from day one.

As a Senior Manager, Early Clinical Development, Clinical Pharmacology Studies, you will be embedded in the heart of early clinical development focused in clinical pharmacology. You will not be watching from the sidelines - you will be designing and providing clinical oversight for the clinical studies that move promising compounds from concept into patients' hands. From drafting protocols and informed consent documents, reviewing clinical data for emerging trends, and authoring and/or reviewing clinical study reports, your fingerprints will be on every critical milestone of a clinical study. That is not a small thing - that is science with stakes.

What Your Day-to-day Actually Looks Like:

• Collaborate with cross-functional teams consisting of internal and external stakeholders to bring rigour and clarity to complex, fast-moving, early development clinical pharmacology studies.
• Craft the blueprint – Develop and refine protocols and ICF documents, present them to governance committees, and ensure every detail supports the science.
• Protect data integrity – Collaborate with data management to design data-focused eCRFs and contribute to Data Review Plans that are effective.
• Tell the scientific story – Author and review clinical study reports and contribute to regulatory submissions (INDs, IBs, DSURs, etc) which open doors to health authorities.
• Raise the bar on-site – Build training materials and present at site initiation visits and investigator meetings so study sites are equipped to deliver high-quality data and proper care for study participants.
• Keep a finger on the pulse – Ongoing monitoring/review for clinical trends to ensure the safety of our study participants.

What You Will Gain Beyond The Job Title:

• Depth of scientific impact - Work across the lifecycle of early development clinical pharmacology studies (from phase 1 through phase 2a).
• A global stage - Partner internationally with KOLs, regulatory bodies, and cross-functional teams.
• A clear growth trajectory - Reporting to the Executive Director of Clinical Science, you will have both the support of experienced leadership and the autonomy to build your capabilities.
• The frontier of clinical pharmacology in early drug development - Work in the dynamic early development therapeutic areas of immunology, cardiovascular, haematology, and oncology.
• A culture that backs you - Be part of a team that challenges each other and champions each other in equal measure.

You will thrive here if you…

• Hold a degree in Life Sciences (MD, PhD, PharmD, MS, RN, or equivalent) and bring 2+ years of experience in early drug development focused in clinical pharmacology.
• Author/review clinical contributions to clinical study reports and clinical portions of regulatory documents (e.g., Pre-IND, IND, IB, DSUR, PSUR, Orphan Annual Reports, HA, EC, IRB responses and contributions to regulatory submissions).
• Proficient knowledge of GCP/ICH, early drug development clinical pharmacology, study designs, statistics, clinical operations, etc.
• Can identify things others miss and care about getting it right.
• Are comfortable navigating ambiguity - shifting priorities do not throw you, they energise you.
• Bring solid medical writing skills and translate complex science into clear, compelling documents.
• Have intermediate skills in Microsoft Word/Excel/PowerPoint and data review tools (e.g., patient profiles/narratives, report generating tools, etc).

Why BMS? Why now? BMS has a bold ambition to transform patients' lives through science. In this department, it means being on the forefront of early drug development clinical pharmacology studies in support of tackling diseases that rob people of their quality of life. BMS is at a pivotal moment in its early drug development clinical pharmacology pipeline, and the clinical scientists we bring on board today help define what is possible tomorrow.

A truly global role with approximately 10 – 20% domestic and international travel required.

We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway.

How We Work: Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities.

Supporting People With Disabilities: BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer.

Data Protection: We will never request payments, financial information, or social security numbers during our application or recruitment process. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.