At a Glance
- Tasks: Lead the scaling of chemical processes from lab to kilo lab, ensuring safety and efficiency.
- Company: Biosynth is a global leader in life sciences reagents and custom manufacturing services.
- Benefits: Enjoy a dynamic work environment with opportunities for career development and innovation.
- Why this job: Make a real impact in process development while leading a talented team in a collaborative setting.
- Qualifications: MSc or PhD in Chemistry or Chemical Engineering with extensive experience in process development.
- Other info: Own transport required to reach our site; hands-on leadership role in a cutting-edge facility.
The predicted salary is between 48000 - 72000 £ per year.
We are establishing a cutting-edge Kilo Lab facility and are seeking an experienced Process Development & Scale-Up Manager to lead the way! If you are a skilled chemist or chemical engineer with a passion for process optimization, scale-up and innovation, this is your opportunity to make a real impact. In this hands-on leadership role, you will be at the forefront of scaling up robust, cost-efficient, and safe chemical processes from laboratory to kilo lab scale (up to 60 litres). You will drive process development, technology transfer, and continuous improvement, ensuring smooth transitions from synthetic labs to production. This role offers a dynamic, collaborative, and fast-paced environment, where you will lead a talented team, oversee safety and compliance, and shape the future of our kilo lab operations. If you're looking for a challenging and rewarding opportunity in process development, we want to hear from you!
Key Responsibilities
- Responsibility, supervision and monitoring of all development processes within laboratory
- Planning and scheduling coordination of process development in collaboration with other departments and project manager(s)
- Hands-on Scale-up of robust, cost-efficient and safe processes from laboratory to ‘kilo lab’ scale (up to 60 litres)
- Coordinate the development of processes for tech transfer from Synthetic labs to ‘Kilolab’ or Staad production site.
- Overseeing of EHS within the ‘Kilo Lab’ laboratory whilst maintaining a high standard of order and cleanliness
- Ascertain the required Safety Risk assessments for scale up processes and the potential impact
- Documentation of the work in ELNs, Batch Records, reports and transfer protocols
- Organising the ordering of project chemical requirements
- Review and recommend new potential equipment or technology for ‘Continuous Improvement Incentive’
- Recruitment and career development of direct reports
- Fostering a supportive culture among R&D teams and process development teams across Biosynth
Essential Candidate Requirements
- MSc or PhD in Organic Chemistry, Chemical Engineering, or related field
- Extensive previous experience in chemical process development and scale-up roles within the pharmaceutical, chemical, CDMO or related industries
- Experience leading and supporting employees in a process development setting
- Experienced in the design, development and optimisation of chemistry routes and processes for the scale-up of novel Products, API’s, intermediates and raw materials
- Experienced in the handling of hazardous chemistry on scale in the ‘Kilolab’ (e.g. inert transfer of flammable solvents & pyrophoric reagents, dealing with release of highly flammable gases etc.)
- Mastered the use of different isolation/purification techniques such as crystallization, distillation, (automated) column chromatography (normal/reverse phase).
- Experience in transferring upscaled processes to production and providing ongoing support to production teams
- Familiarity with process development planning, equipment maintenance, and safety regulations in a chemical manufacturing environment
- Ability to troubleshoot equipment issues and initiate maintenance tasks to ensure operational efficiency
- Strong problem-solving skills and the ability to troubleshoot process issues during scale-up
- Attention to detail and a commitment to ensuring robust, cost-efficient, and safe processes
- Strong organizational and communication skills to coordinate shift operations and liaise with other departments
- Leadership qualities and the ability to motivate and inspire employees to achieve production goals
- Commitment to safety and cleanliness in the production environment, including adherence to standard operating procedures (SOPs).
Desirable Candidate Requirements
- Previous experience in a leadership or supervisory role within a kilo lab environment
- Familiarity with risk assessment techniques, safety protocols, and regulatory requirements for chemical processes
- Experience with technology transfer processes and documentation requirements for production-scale implementation
- Knowledge of production equipment operation and troubleshooting techniques to address chemical issues during production
- Knowledge of SAP and QMS systems
- Ability to effectively convey technical information to non-technical stakeholders and decision-makers
- Hands-on attitude and positive mindset (“play to win”).
- Resilient when faced by challenges and resistant to time pressure.
- You will need your own transport to be able to get to our site.
About us
Biosynth® is an innovative life sciences reagents, custom synthesis and manufacturing services company headquartered in Staad, Switzerland. We are by scientists, for scientists, securing supply chains with consistent quality, across the globe. As a trusted supplier, manufacturer and partner to the pharmaceutical, life science and diagnostic industries, as well as food, agrochemical and cosmetic customers, we have facilities on three continents and a rapid global distribution network. Our main production laboratories are located in Switzerland, the UK, Slovakia and China, with peptide and antibody production in the US, the Netherlands. Bioconjugation projects are carried out in Germany, Enzyme projects are based in Austria and biological IVD reagents in Ireland.
Kilolab Process development & Scale up Manager employer: Biosynth
Contact Detail:
Biosynth Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Kilolab Process development & Scale up Manager
✨Tip Number 1
Network with professionals in the chemical engineering and process development fields. Attend industry conferences, workshops, or webinars to meet potential colleagues and learn about the latest trends and technologies that could be relevant to our kilo lab operations.
✨Tip Number 2
Familiarise yourself with the specific safety protocols and risk assessment techniques used in kilo lab environments. This knowledge will not only help you stand out but also demonstrate your commitment to safety and compliance, which is crucial for this role.
✨Tip Number 3
Showcase your leadership skills by discussing any previous experiences where you successfully led a team through a challenging project. Highlight how you motivated your team and ensured smooth collaboration across departments, as this is key for the role at StudySmarter.
✨Tip Number 4
Prepare to discuss your hands-on experience with scale-up processes and the specific techniques you've used for optimisation. Being able to articulate your practical knowledge will give you an edge in demonstrating your suitability for the position.
We think you need these skills to ace Kilolab Process development & Scale up Manager
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in chemical process development and scale-up. Emphasise your leadership roles and any specific projects that align with the responsibilities outlined in the job description.
Craft a Compelling Cover Letter: Write a cover letter that showcases your passion for process optimisation and innovation. Mention specific examples of how you've successfully scaled up processes in previous roles, and how you can contribute to the Kilo Lab facility.
Highlight Safety and Compliance Experience: Given the importance of safety in this role, ensure you detail your experience with safety protocols, risk assessments, and compliance in chemical environments. This will demonstrate your commitment to maintaining high standards.
Showcase Problem-Solving Skills: In your application, provide examples of challenges you've faced in process development and how you resolved them. This will illustrate your strong problem-solving skills and ability to troubleshoot during scale-up.
How to prepare for a job interview at Biosynth
✨Showcase Your Technical Expertise
Be prepared to discuss your experience in chemical process development and scale-up. Highlight specific projects where you successfully transitioned processes from lab to kilo lab scale, focusing on the challenges faced and how you overcame them.
✨Demonstrate Leadership Skills
As a potential leader, it's crucial to convey your ability to motivate and inspire teams. Share examples of how you've supported employees in a process development setting and fostered a collaborative culture among R&D teams.
✨Emphasise Safety and Compliance Knowledge
Given the importance of safety in this role, be ready to discuss your familiarity with EHS protocols and risk assessment techniques. Provide examples of how you've maintained safety standards in previous positions, especially in handling hazardous materials.
✨Prepare for Problem-Solving Scenarios
Expect questions that assess your problem-solving skills, particularly in troubleshooting equipment issues during scale-up. Think of specific instances where you identified and resolved process issues, and be ready to explain your thought process.