Senior Research Associate, Bioanalytical & Molecular Assays - Ligand Binding Assays in Oxford

Role Overview

Moderna’s Bioanalytical and Molecular Assays – Ligand Binding Assays team seeks an individual contributor to advance the development of innovative m RNA medicines.

The role involves developing, validating, and executing bioanalytical assays that generate critical pharmacodynamic and immunogenicity data supporting clinical programs in a fast‑paced, high‑performing laboratory environment.

Responsibilities

• Support the development, optimization, and validation of ligand‑binding and cell‑based assays to evaluate pharmacodynamic and immunogenicity endpoints for novel m RNA‑derived proteins.
• Perform clinical sample testing across a range of biological matrices in compliance with Good Clinical Laboratory Practice (GCLP) requirements using Thermo Watson LIMS.
• Deliver assay development and validation activities on schedule to support key program milestones.
• Maintain accurate experimental documentation using electronic laboratory notebooks.
• Support the generation, characterization, establishment, and control of critical reagents.
• Contribute to laboratory operations to ensure an efficient and compliant working environment.
• Prepare Standard Operating Procedures (SOPs), technical reports, and scientific data presentations.
• Review raw experimental data, analytical study reports, and assay validation reports to ensure laboratory activities comply with current regulatory requirements, industry standards, and Moderna quality expectations.
• Confirm that generated data meet both scientific and regulatory expectations.
• Support the procurement, qualification, and implementation of analytical equipment.
• Partner closely with Clinical Operations and Sample Management to define the end‑to‑end clinical sample journey.
• Develop fit‑for‑purpose laboratory manuals that support successful clinical sample management and testing.
• Contribute to a collaborative, high‑performance team focused on developing de novo bioanalytical assays for novel m RNA‑derived proteins.

Qualifications

• A BA/BS in a biological science field and a minimum of 5 years of biotech/pharmaceutical/CRO industry experience; MS with 3+ years of experience is acceptable.
• Experience with Ligand Binding and/or Cell‑Based Assays is required.
• Prior experience performing PK, ADA, or n Ab assays is preferred.
• Experience working in a regulated environment (GLP, GCLP, GMP) is preferred.
• Keen attention to detail, ability to multi‑task, effective communication skills and a strong desire to collaborate with the team are required.
• Ability to effectively communicate program objectives, data analysis and present findings to group team members and key stakeholders.
• Knowledge of GCLP requirements and current industry trends and regulatory expectations associated with analytical science.
• Experience with Watson LIMS and Lab Vantage e LBN would be an advantage.
• A desire to make an impact as part of a high‑growth, transformational company that is bold, relentless, curious, and collaborative.

Benefits

• Competitive healthcare, plus voluntary benefit programs to support your unique needs.
• A holistic approach to well‑being with access to fitness, mindfulness, and mental health support.
• Family building benefits, including fertility, adoption, and surrogacy support.
• Generous paid time off, including vacation, bank holidays, volunteer days, sabbatical, global recharge days, and a discretionary year‑end shutdown.
• Savings and investments to help you plan for the future.
• Location‑specific perks and extras.
• Equal Opportunity and EEO Statement

Moderna is committed to equal opportunity in employment and non‑discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law.

We consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Moderna is committed to offering reasonable accommodation or adjustments to qualified job applicants with disabilities.

Any applicant requiring an accommodation or adjustment in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations and Adjustments team at leavesandaccommodations@modernatx. com.

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