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For Companies At a Glance
- Tasks: Join a dynamic lab to research cancer and characterise novel therapeutic targets.
- Company: World-leading Cancer Research UK Manchester Institute with cutting-edge facilities.
- Benefits: Collaborative environment, access to advanced resources, and impactful research opportunities.
- Why this job: Make a real difference in cancer treatment while working with top experts in the field.
- Qualifications: PhD in biochemistry or cell biology; experience in cancer models and cell signalling required.
- Other info: Exciting career growth in a state-of-the-art research centre.
The predicted salary is between 36000 - 60000 £ per year.
About The Role
Dr Claus Jorgensen, Group Leader of the Systems Oncology Group, is looking for a Postdoctoral Scientist to join his group. This is a great opportunity for a self-motivated, innovative, meticulous and organised candidate who is keen to work in a dynamic laboratory undertaking cutting edge research.
The goal of the Systems Oncology Group is to understand how the tumour microenvironment, and the desmoplastic reaction, regulates tumour cell function and therapeutic response in pancreatic ductal adenocarcinoma. We have identified a novel target regulating the interactions between tumour cells and the microenvironment, which we believe may be a target for future therapeutic intervention.
The objective of this post is to functionally characterise this target and its role in regulating tumour cells, host cells, and their interactions. Specifically, the post holder will use a number of
in vitro
cell biology assays to assess cell function and biochemical assays to assess cell signalling
in vitro
; this will include functional CRISPR analysis, pharmacological studies, enzyme assays and mass spectrometry analysis in 2D and 3D cell models. Tumour models will be analysed by IF/IHC, proteomics, genomics and transcriptionally as well as testing novel combination treatments using available
in vivo
models (see Hutton et al Cancer Cell 2021, Lee et al Nat Comm 2021 and Below et al Nat Mat This is a project for a highly collaborative individual seeking to make a difference in a very hard to treat cancer.
About You
You should have a PhD in biochemistry, cell biology or a related field. Experience in protein biochemistry, analysis of cell signalling and use of
in vitro
models of cancer is required. Experience with
in vivo
tumour models and immunology is desirable. Key qualities include independent thinking, ability to work in a team and good communication skills, all of which are needed to efficiently work in a multidisciplinary team.
Why choose Cancer Research UK Manchester Institute?
The Cancer Research UK Manchester Institute ), an Institute of The University of Manchester ), is a world-leading centre for excellence in cancer research. The Institute is core funded by Cancer Research UK ), the largest independent cancer research organisation in the world. In spring 2023 the Institute moved into the new Paterson Building, a £150 million flagship purpose-built biomedical research centre directly attached to The Christie NHS Foundation Trust ), in South Manchester.
We are partnered with The Christie NHS Foundation Trust, one of the largest cancer treatment centres in Europe. These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.
How to apply?
To Apply For This Position Please Visit Our Website
Informal enquiries can be directed to Dr Claus Jorgensen via email:
Closing date: Sunday 26th October 2025
1st round interviews: w.c. 10th November 2025
Postdoctoral Scientists employer: Bionow
Contact Detail:
Bionow Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Postdoctoral Scientists
✨Tip Number 1
Network like a pro! Reach out to current or former employees at the Cancer Research UK Manchester Institute. A friendly chat can give us insights into the team culture and maybe even a referral!
✨Tip Number 2
Prepare for the interview by diving deep into the latest research from the Systems Oncology Group. Show us you’re not just interested in the role, but that you’re genuinely excited about the work being done!
✨Tip Number 3
Practice your pitch! Be ready to explain how your skills in protein biochemistry and cell signalling make you the perfect fit for this postdoc position. Confidence is key, so let’s nail that delivery!
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen. Plus, it shows us you’re serious about joining our innovative team!
We think you need these skills to ace Postdoctoral Scientists
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to highlight your experience in biochemistry and cell biology. We want to see how your skills align with the role, so don’t be shy about showcasing relevant projects or research!
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to express your passion for cancer research and explain why you’re excited about joining our Systems Oncology Group. Let us know how you can contribute to our mission.
Showcase Your Collaborative Spirit: Since this role requires working in a multidisciplinary team, make sure to highlight any past experiences where you’ve successfully collaborated with others. We love seeing candidates who thrive in a team environment!
Apply Through Our Website: Don’t forget to apply through our website! It’s the best way to ensure your application gets to us directly. Plus, it shows you’re serious about joining our fantastic team at the Cancer Research UK Manchester Institute.
How to prepare for a job interview at Bionow
✨Know Your Research
Make sure you’re well-versed in the latest findings related to pancreatic ductal adenocarcinoma and the tumour microenvironment. Familiarise yourself with the work of Dr Claus Jorgensen and his team, as well as the specific methodologies they use, like CRISPR analysis and mass spectrometry.
✨Showcase Your Skills
Prepare to discuss your experience in protein biochemistry and cell signalling. Be ready to provide examples of how you've successfully used in vitro models in your previous research, and highlight any relevant projects that demonstrate your independent thinking and collaborative spirit.
✨Ask Insightful Questions
During the interview, ask questions that show your genuine interest in the role and the research. Inquire about the current challenges the team is facing or how they envision the future of their research. This not only shows your enthusiasm but also your critical thinking skills.
✨Demonstrate Team Spirit
Since this position requires working in a multidisciplinary team, be prepared to discuss how you’ve effectively collaborated with others in the past. Share specific examples of how you’ve contributed to team success and how you handle conflicts or differing opinions.
