Revvity's R&D Bioprocessing department pioneers advanced expression platforms that power the manufacturing of next-generation biotherapeutics. Our portfolio includes specialized mammalian host cell lines, our innovative transposon-based expression system for rapid identification of high-expressing clones, and gene editing capabilities that enable custom cell line engineering. These technologies support both protein-based therapeutics and viral vector production, addressing the evolving needs of the biopharma industry.
Job summary
Join Revvity's Bioprocessing R&D team as a Senior Scientist, where you will drive innovation in our CHOSOURCE Expression platform. This is a hands-on, lab-based product development role focused on advancing CHO-based expression technologies for biotherapeutic production. You will tackle real-world expression challenges, from optimizing productivity to enabling successful expression of diverse biologics and translatingyour findings into commercial products that empower biopharma customers worldwide. As a senior member of the team, you will play a key role in shaping the scientific direction of the platform and contributing to a culture of innovation and continuous improvement.
Key responsibilities:
- Lead independent research projects to develop and validate new CHOSOURCE platform features for both stable and transient expression applications, from experimental design through execution, analysis, and troubleshooting
- Identify and evaluate emerging technologies and scientific trends relevant to CHO-based expression systems, proposing novel approaches to enhance platform performance and differentiation
- Apply gene editing technologies to engineer and develop novel host cell lines with enhanced production characteristics
- Collaborate with peer senior scientists to drive cross-functional problem-solving and advance platform capabilities
- Foster collaborative relationships within the team and across Revvity departments
- Maintain comprehensive laboratory documentation and develop standard operating procedures
- Present clear, concise data at both internal and external meetings
- Support IP generation and regulatory documentation as needed for product commercialization
Essential Competencies & Requirements:
- Ph.D. in life science (molecular biology, biochemistry, cell biology or genetics) with a minimum of 5 years of postdoctoral experience or industry experience in a relevant scientific field
- In-depth knowledge of CHO cell line development, including stable pool generation, single cell cloning, and clone screening
- Strong expertise in gene editing technologies with hands-on experience in mammalian cell line engineering, including targeted integration, gene knockout, and knock-in strategies
- Practical understanding of the challenges associated with expressing diverse biologics including difficult-to-express proteins and more complex biologics
- Advanced molecular biology skills, including expertise in diverse cloning methods (Gibson assembly, Golden Gate assembly), PCR, qPCR, and ddPCR
- Experience applying Design of Experiment (DoE) methodologies to experimental design
- Strong analytical mindset with ability to troubleshoot complex technical problems systematically
- Proven ability to work effectively in cross-functional, fast-paced environments
- Exceptional team collaboration skills with strong communication abilities and meticulous attention to detail
- Demonstrated scientific curiosity with a proactive approach to knowledge development and a track record of translating research findings into tangible products
Join our team and help shape the future of biotherapeutic production technologies at Revvity.
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