At a Glance
- Tasks: Lead a team of biostatisticians to shape study designs and ensure data integrity.
- Company: Bicycle Therapeutics, a pioneering clinical-stage pharmaceutical company.
- Benefits: Hybrid working model, competitive salary, and opportunities for professional growth.
- Other info: Join a culture that values adventure, dedication, and teamwork.
- Why this job: Make a real impact on innovative therapies that change lives.
- Qualifications: Expertise in biostatistics and leadership experience in clinical development.
The predicted salary is between 100000 - 150000 £ per year.
Bicycle Therapeutics is a clinical‑stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics.
Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry.
This constraint facilitates target binding with high affinity and selectivity, making Bicycle® molecules attractive candidates for drug development.
The company is evaluating nuzafatide pevedotin (formerly BT5528), a Bicycle® Drug Conjugate (BDC®) targeting Eph A2, a historically undruggable target; a pipeline of Bicycle® Radioconjugates (BRCs) and imaging agents; zelenectide pevedotin (formerly BT8009), a BDC® targeting Nectin‑4, a well‑validated tumor antigen; and, through various partnerships, the use of Bicycle®technology to develop therapies to treat diseases in a range of therapeutic areas.
Bicycle Therapeutics is headquartered in Cambridge, UK, with many key functions and members of its leadership team located in Lexington, Massachusetts, USA.
For more information, visit bicycletherapeutics. com Culture is key and all Bicycle employees actively embrace and role model our company values: We are Adventurous .
We believe it’s the way to deliver extraordinary results for our patients.
We are Dedicated to our Mission .
You can’t change the world if you don’t have determination.
We are One Team .
We only succeed when we work together.
At Bicycle, we benefit from a hybrid style working arrangement, allowing our employees where possible the opportunity to collaborate and engage with their coworkers in person while also benefiting from the flexibility of home remote working.
A typical hybrid arrangement for this role is 3 days onsite per week at our Cambridge, UK, with the remainder of your working week remote.
Job Description Your mission is to provide expert strategic and statistical leadership for Bicycle’s clinical development portfolio.
You will lead a team of biostatisticians, providing quantitative deep thinking to shape study designs, guide program strategy, and ensure the integrity of our clinical data.
As a key leader in the Biometrics function, you will be instrumental in translating complex data into clear, actionable insights that drive our innovative therapies forward for patients.
Your Responsibilities You will lead, coach, and mentor your team of biostatisticians, investing in their professional growth and fostering a culture of high performance and psychological safety.
You will set clear goals and strategic priorities for the biostatistics function, ensuring its work is directly aligned with departmental and organizational objectives.
You will champion the Bicycle Values in all that you do, acting as a role model and embedding a culture of collaboration, accountability, and innovation within your team.
Statistical Strategy
