At a Glance
- Tasks: Lead preclinical strategy for antibody therapies and oversee critical studies.
- Company: Emerging biotechnology company focused on innovative therapeutic programmes.
- Benefits: Competitive salary, career advancement, and the chance to shape groundbreaking therapies.
- Other info: Collaborative environment with opportunities to work cross-functionally.
- Why this job: Make a real impact in biotech by advancing life-changing treatments.
- Qualifications: Strong in vivo pharmacology and preclinical development experience required.
The predicted salary is between 80000 - 100000 £ per year.
Barrington James is supporting an emerging biotechnology company that is looking to appoint a senior preclinical development leader to support the progression of antibody-based therapeutic programmes towards clinical development. This is a hands-on strategic role for someone with strong in vivo pharmacology and preclinical development experience, who can help shape the right study strategy from early proof-of-concept through IND/CTA-enabling activity.
Key Responsibilities
- Lead preclinical strategy across early-stage antibody therapeutic programmes.
- Design, oversee and interpret in vivo pharmacology, PK/PD, toxicology and safety studies.
- Provide input on disease model selection, species relevance, endpoints, dose rationale and translational value.
- Manage outsourced studies with CROs, consultants and external study directors.
- Interpret complex in vivo and toxicology data, identifying key risks, limitations and next steps.
- Work cross-functionally with discovery, translational, CMC, regulatory and clinical stakeholders.
- Support candidate selection and IND/CTA-enabling documentation.
Experience Required
- Strong background in in vivo pharmacology, preclinical development or nonclinical strategy.
- Experience progressing antibody-based, biologic or complex therapeutic programmes towards IND/CTA or early clinical development.
- Strong understanding of animal model selection, pharmacology study design, PK/PD, toxicology and translational interpretation.
- Experience managing external CROs and outsourced in vivo studies.
- Ability to challenge study design, interpret complex data and translate findings into clear development recommendations.
Head of Preclinical Development in Slough employer: Barrington James
Barrington James offers an exceptional work environment for the Head of Preclinical Development, fostering a culture of innovation and collaboration within the biotechnology sector. Employees benefit from a hands-on approach to strategic leadership, ample opportunities for professional growth, and the chance to contribute to groundbreaking antibody-based therapeutic programmes in a dynamic and supportive setting. Located in a vibrant area, the company promotes a healthy work-life balance and encourages continuous learning, making it an attractive choice for those seeking meaningful and rewarding employment.
StudySmarter Expert Advice🤫
We think this is how you could land Head of Preclinical Development in Slough
✨Get Involved in Local Research Communities
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We think you need these skills to ace Head of Preclinical Development in Slough
Some tips for your application 🫡
Show Off Your Lab Skills:In the biotechnology field, it's super important to highlight your lab experience in your CV. Be sure to mention specific techniques or instruments you've mastered (think PCR, gel electrophoresis, etc.) and any relevant projects you've worked on. This will show Barrington James that you have the hands-on skills they need.
Tailor Your Technical Skills:Make sure to emphasise your technical skills, especially those relevant to the biotechnology sector. Include any software tools or programming languages you've used, like R or Python for data analysis, which could be key for this role at Barrington James.
Craft a Compelling Cover Letter:Since this is a full-time role, your cover letter should reflect not only your passion for biotechnology but also your long-term career ambitions. Share why you're excited about the work that Barrington James does and how you envision contributing to their goals. This shows that you’re not just looking for any job, but you're genuinely invested in this opportunity.
Include Your Papers and Projects:If you've published any papers or contributed to significant projects, mention them! These documents can boost your application and provide tangible evidence of your expertise in the biotechnology field. Don’t forget to link to any relevant publications or project summaries—this can set you apart from other candidates.
How to prepare for a job interview at Barrington James
✨Brush Up on Lab Techniques
Since you're eyeing a full-time gig in biotechnology, make sure you're well-versed in the lab techniques relevant to the role. Be ready to talk about PCR, CRISPR, or any specific methods mentioned in the job description at Barrington James. You might even be asked to demonstrate your understanding of these processes.
✨Know Your Bioinformatics Tools
Get comfortable with bioinformatics tools that are commonly used in the industry, like BLAST or Bioconductor. These are key in biotechnology, and having hands-on experience or at least familiarity can set you apart. Prepare to discuss any relevant projects you've worked on, especially if they involved data analysis or genomic research.
✨Show Your Teamwork Skills
Biotech often involves collaboration across multiple disciplines. Be ready to share stories that highlight your teamwork and communication skills, especially in research projects. Think about working with different teams at university or any internships – this is where you can show how well you fit into Barrington James's culture.
✨Research Recent Biotech Innovations
Stay updated on the latest trends and breakthroughs in biotechnology. Knowing what's happening in the field can help you engage in more meaningful discussions during your interview. Bring up recent articles or advancements that excite you, especially those related to the work being done at Barrington James. This shows your passion for the industry!
