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- Tasks: Lead and manage multiple hematology clinical trials from start to finish.
- Company: Join a dynamic biotech company focused on innovative clinical development.
- Benefits: Enjoy remote work flexibility and opportunities for professional growth.
- Why this job: Make a real impact in healthcare while collaborating with top professionals in the field.
- Qualifications: 7+ years in clinical trial management, especially in hematology/oncology.
- Other info: Ideal for those passionate about advancing medical research and patient care.
The predicted salary is between 54000 - 84000 £ per year.
Job Description: Senior Clinical Project Manager – Hematology
Location: Remote (UK)
Department: Clinical Development / Clinical Operations
Reports To: Director, Clinical Operations / VP, Clinical Development
Position Summary
We are seeking a highly motivated and experienced Senior Clinical Project Manager (Sr. CPM) to join our Clinical Operations team. The Sr. CPM will be responsible for the operational planning, execution, and oversight of three hematology clinical programs spanning early- to late-phase development. This individual will play a pivotal role in ensuring that studies are delivered on time, within budget, and in compliance with applicable regulations, SOPs, and GCP standards.
The ideal candidate will bring strong leadership, cross-functional collaboration, and vendor management expertise, along with deep experience in hematology and/or oncology trials.
Key Responsibilities
Clinical Trial Leadership & Execution
- Lead the planning, initiation, execution, and closure of multiple clinical trials across three hematology assets.
- Serve as the primary operational contact for cross-functional study teams, investigators, and CROs/vendors.
- Develop and manage study timelines, milestones, risk mitigation strategies, and budget forecasts.
- Ensure clinical trial deliverables are met according to quality standards, ICH-GCP, regulatory guidelines, and company SOPs.
Vendor & CRO Oversight
- Select, contract, and manage CROs and third-party vendors (labs, imaging, data management, central monitoring, etc.).
- Oversee vendor performance and drive accountability for deliverables, timelines, and quality.
- Negotiate budgets and contracts to align with program goals.
Cross-Functional Collaboration
- Partner with Clinical Development, Regulatory Affairs, Biometrics, Pharmacovigilance, and Medical Affairs to support seamless trial execution.
- Collaborate with Translational/CMC colleagues to align clinical operations with asset-specific requirements.
- Support regulatory submissions (INDs, NDAs/BLAs, CTAs), briefing packages, and responses to health authorities.
Operational Excellence
- Lead study team meetings, prepare agendas, track action items, and maintain documentation.
- Provide input into protocol design, ICFs, CRFs, monitoring plans, and study manuals.
- Monitor site performance, patient enrollment, and data quality; proactively identify and resolve issues.
- Support audit and inspection readiness across programs.
Leadership & Mentorship
- Mentor and support junior clinical operations staff as required.
- Contribute to process improvement initiatives within Clinical Operations.
- Represent Clinical Operations in cross-functional and governance meetings.
Qualifications & Experience
- Life sciences degree (BSc or higher); advanced degree a plus.
- 7+ years of clinical trial management experience, including 3+ years in hematology/oncology trials.
- Proven track record in managing Phase I–III global clinical studies.
- Strong knowledge of ICH-GCP, EMA/MHRA guidelines, and regulatory frameworks in Europe/UK.
- Demonstrated success in CRO/vendor management and budget oversight.
- Excellent communication, organizational, and leadership skills.
- Ability to work effectively in a remote, fast-paced biotech environment with multiple priorities.
Senior Clinical Project Manager employer: Barrington James
Contact Detail:
Barrington James Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Clinical Project Manager
✨Tip Number 1
Network with professionals in the clinical research field, especially those who have experience in hematology and oncology trials. Attend relevant conferences or webinars to connect with potential colleagues and learn about industry trends.
✨Tip Number 2
Familiarise yourself with the latest regulations and guidelines related to clinical trials in the UK, particularly ICH-GCP and EMA/MHRA standards. This knowledge will not only boost your confidence but also demonstrate your commitment to compliance during interviews.
✨Tip Number 3
Prepare to discuss specific examples of your leadership and project management experiences in previous roles. Highlight how you successfully managed timelines, budgets, and vendor relationships, as these are crucial for the Senior Clinical Project Manager position.
✨Tip Number 4
Showcase your ability to collaborate across functions by preparing anecdotes that illustrate your teamwork skills. Be ready to explain how you’ve worked with various departments like Regulatory Affairs and Medical Affairs to ensure smooth trial execution.
We think you need these skills to ace Senior Clinical Project Manager
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in clinical trial management, particularly in hematology or oncology. Emphasise your leadership roles and any specific achievements that align with the job description.
Craft a Compelling Cover Letter: Write a cover letter that showcases your passion for clinical research and your understanding of the role. Mention specific projects you've led and how they relate to the responsibilities outlined in the job description.
Highlight Relevant Skills: In your application, clearly outline your skills in vendor management, cross-functional collaboration, and regulatory compliance. Use examples to demonstrate how you've successfully managed budgets and timelines in previous roles.
Proofread Your Application: Before submitting, carefully proofread your application for any spelling or grammatical errors. A polished application reflects your attention to detail, which is crucial in clinical project management.
How to prepare for a job interview at Barrington James
✨Showcase Your Leadership Skills
As a Senior Clinical Project Manager, you'll need to demonstrate strong leadership abilities. Prepare examples from your past experiences where you successfully led clinical trials or teams, highlighting how you managed challenges and drove projects to completion.
✨Understand the Hematology Landscape
Familiarise yourself with the latest trends and developments in hematology and oncology. Being able to discuss recent studies or breakthroughs will show your passion for the field and your commitment to staying informed.
✨Prepare for Vendor Management Questions
Expect questions about your experience with CROs and vendor management. Be ready to discuss specific instances where you negotiated contracts, managed vendor performance, and ensured quality deliverables.
✨Demonstrate Cross-Functional Collaboration
Highlight your ability to work with various departments such as Regulatory Affairs and Medical Affairs. Prepare examples of how you've successfully collaborated with different teams to achieve common goals in clinical trials.