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- Tasks: Join a dynamic team to drive innovative cancer research and biomarker analysis.
- Company: AstraZeneca, a leader in oncology with a commitment to making a difference.
- Benefits: Collaborative environment, career growth, and the chance to impact patient outcomes.
- Why this job: Be at the forefront of translational science and help eliminate cancer as a cause of death.
- Qualifications: BSc or MSc in a relevant field with 3 years of industry experience.
- Other info: Empowered team culture focused on courage, curiosity, and collaboration.
The predicted salary is between 36000 - 60000 £ per year.
Senior Scientist in Translational Pathology, Oncology
We are seeking a Senior Scientist to join the Translational Pathology group in Oncology R&D Translational Medicine department, where you will be at the forefront of the evolution of translational science for a global oncology group in AstraZeneca!
You will have the opportunity to impact an industry-leading portfolio of programs from early clinical development of novel therapeutics through to post-marketing opportunities that support approved targeted therapies.
At AstraZeneca, we work together across global boundaries to make an impact and find answers to challenges. We do this with the utmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people\’s exceptional skills with those of people from all over the globe!
Major Responsibilities and Accountabilities:
This role is a lab-based position working in a Good Clinical Practice (GCP) environment.
In this role you will be part of the Translational team driving the successful operations of a GCP lab, using the best available science and technology to execute routine biomarker analysis and interpret and communicate the data as part of a matrix team. Your work will inform clinical decisions for selecting therapeutically relevant doses and schedules, as well as building our understanding of key cancer pathway interactions to guide rational drug combinations. In addition, your work will help define novel mechanisms of resistance to targeted therapies by studying tumours at relapse.
Skills and experience:
- BSc or MSc in Biomedical Science or a relevant scientific discipline.
- Experience in an NHS or related clinical setting and HCPC registration is highly desirable.
- Pharmaceutical industry experience is desirable.
- Strong experience in manual or automated immunohistochemistry (brightfield or fluorescence)
- Strong experience in microtomy
- Strong experience working to Good Clinical Practice or ISO15189.
- Strong experience in development and validation of biomarker assays
- Experience working with human tissues and tissue-based histopathology methods
- Knowledge or experience in one or more AZ portfolio areas: tumour drivers and resistance, DNA damage response (DDR), immuno-oncology (IO) and antibody drug conjugates (ADC)
- Experience of tracking and/or managing human tissues using sample tracking software (e.g. BSI, SAPIO, Azenta etc.)
- Highly organized and self-motivated with attention to detail.
- Ability to work independently as well as collaboratively within a team to deliver to projects
- Strong written and oral communication skills
- Strong ability to troubleshooting and critically analyse data
Desirable/Advantageous – Although training will be given, experience in the following areas would provide a distinct advantage:
- Previous pharmaceutical industry experience
- Experience with digital image analysis solutions (e.g. ImageJ, HALO, Visiopharm etc)
- Skills in developing multiplexed immunohistochemistry or in situ hybridization (ISH) assays
- Career exposure to the pharmaceutical industry and the drug development process
AstraZeneca offers an environment where courage, curiosity, and collaboration thrive. With a vision to eliminate cancer as a cause of death, we unite cutting-edge science with the latest technology to achieve breakthroughs. Empowered at every level, our team is driven by patient outcomes, making bold decisions and taking smart risks. Join us in pioneering collaborative research with an unrivaled scientific community, working inclusively to expedite research in challenging cancers.
Ready to make an impact? Apply now and be part of a team dedicated to improving lives through innovative oncology solutions!
To find out more:
Group site: https://www.astrazeneca.com/
Our social media, Follow us on LinkedIn: AstraZeneca
Inclusion & Diversity: https://careers.astrazeneca.com/inclusion-diversity
Career site: https://careers.astrazeneca.com/
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Senior Scientist in Translational Pathology, Oncology employer: AstraZeneca
Contact Detail:
AstraZeneca Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Scientist in Translational Pathology, Oncology
✨Network Like a Pro
Get out there and connect with people in the industry! Attend conferences, webinars, or local meetups related to oncology and translational pathology. You never know who might have a lead on your dream job or can introduce you to someone at AstraZeneca.
✨Show Off Your Skills
When you get the chance to chat with potential employers, make sure to highlight your experience with immunohistochemistry and biomarker assays. Share specific examples of how you've tackled challenges in the lab – this will show them you're the real deal!
✨Be Ready for the Interview
Prepare for interviews by brushing up on your knowledge of tumour drivers, DNA damage response, and immuno-oncology. Be ready to discuss how your skills align with AstraZeneca's mission to eliminate cancer as a cause of death. Confidence is key!
✨Apply Through Our Website
Don't forget to apply directly through the AstraZeneca careers site! This not only shows your interest but also ensures your application gets into the right hands. Plus, it’s a great way to stay updated on new opportunities that pop up.
We think you need these skills to ace Senior Scientist in Translational Pathology, Oncology
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to the Senior Scientist role. Highlight your relevant experience in translational pathology and any specific skills that match the job description, like immunohistochemistry or biomarker assays.
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you're passionate about oncology and how your background makes you a perfect fit for AstraZeneca's mission. Keep it concise but impactful!
Showcase Your Team Spirit: Since collaboration is key at AstraZeneca, don’t forget to mention your experience working in teams. Share examples of how you've contributed to group projects and how you can bring that spirit to our Translational Pathology group.
Apply Through Our Website: We encourage you to apply directly through our website. It’s the best way to ensure your application gets into the right hands. Plus, you’ll find all the details you need about the role and our company culture there!
How to prepare for a job interview at AstraZeneca
✨Know Your Science
Make sure you brush up on the latest advancements in translational pathology and oncology. Be prepared to discuss specific techniques like immunohistochemistry and microtomy, as well as your experience with biomarker assays. This shows that you're not just familiar with the basics but are genuinely engaged with the field.
✨Showcase Your Experience
Highlight your previous industry experience, especially any work related to human tissues and tissue-based histopathology methods. Be ready to share examples of how you've used sample tracking software or developed multiplexed assays. This will demonstrate your hands-on skills and ability to contribute from day one.
✨Communicate Clearly
Strong communication skills are key in this role. Practice explaining complex scientific concepts in a clear and concise manner. You might be asked to present data or findings, so being able to articulate your thoughts effectively will set you apart from other candidates.
✨Emphasise Teamwork
AstraZeneca values collaboration, so be prepared to discuss your experience working in teams. Share examples of how you've contributed to group projects and how you handle challenges within a team setting. This will show that you can thrive in a collaborative environment and align with their company culture.