Senior Scientist - Genetic Toxicology
Senior Scientist - Genetic Toxicology

Senior Scientist - Genetic Toxicology

Full-Time 60000 - 80000 £ / year (est.) No home office possible
AstraZeneca

At a Glance

  • Tasks: Lead innovative genetic toxicology projects and drive high-throughput imaging methodologies.
  • Company: Join a pioneering team at the Cambridge Discovery Centre.
  • Benefits: Competitive salary, collaborative environment, and opportunities for professional growth.
  • Other info: Dynamic role with a focus on innovation and collaboration.
  • Why this job: Make a real impact on drug discovery and development with cutting-edge science.
  • Qualifications: Experience in genetic toxicology and strong data analysis skills.

The predicted salary is between 60000 - 80000 £ per year.

Based in our Discovery Centre on the Cambridge Addenbrookes campus, this role sits at the heart of Genetic Toxicology, working alongside colleagues in Clinical Pharmacology and Safety Sciences to advance the genotoxicity assessment of new medicines. The position focuses on high-throughput imaging and screening methodologies to generate robust, decision-enabling data that informs safety assessment across drug discovery and development. Operating in a highly collaborative environment, this role combines hands-on scientific delivery, strategic assay optimisation, and data-driven insight to help shape the next generation of therapeutics. Ready to ask bold questions and follow the science?

Accountabilities:

  • Lead the design, execution, and interpretation of high-content imaging and other genotoxicity assays to support projects from early discovery through development.
  • Drive optimisation and innovation in imaging-based and complementary genetic toxicology methodologies, enhancing throughput, robustness, and biological relevance.
  • Apply advanced data analysis and visualisation approaches to integrate complex datasets and communicate clear conclusions to multidisciplinary teams.
  • Interpret and apply ICH S2(R1), OECD, and pharmaceutical regulatory expectations to ensure studies are designed and delivered to support regulatory submissions.
  • Oversee non-GLP genotoxicity studies with CROs and external partners, ensuring scientific quality, compliance with internal standards, and timely delivery of milestones.
  • Prepare high-quality study reports and technical documentation, maintaining rigorous data integrity and documentation practices.

Senior Scientist - Genetic Toxicology employer: AstraZeneca

As a Senior Scientist in Genetic Toxicology at our Cambridge Discovery Centre, you will thrive in a dynamic and collaborative work culture that prioritises innovation and scientific excellence. We offer competitive salaries, comprehensive benefits, and ample opportunities for professional growth, all while being part of a vibrant community dedicated to advancing healthcare through cutting-edge research. Join us in shaping the future of therapeutics in a location renowned for its rich scientific heritage and commitment to discovery.
AstraZeneca

Contact Detail:

AstraZeneca Recruiting Team

StudySmarter Expert Advice 🤫

We think this is how you could land Senior Scientist - Genetic Toxicology

✨Tip Number 1

Network like a pro! Reach out to professionals in the genetic toxicology field on LinkedIn or at industry events. We can’t stress enough how valuable personal connections can be in landing that dream job.

✨Tip Number 2

Prepare for interviews by brushing up on your knowledge of high-throughput imaging and screening methodologies. We recommend practising common interview questions and having examples ready that showcase your hands-on experience and strategic thinking.

✨Tip Number 3

Showcase your data analysis skills! Be ready to discuss how you’ve applied advanced data analysis and visualisation approaches in past projects. We want to see how you can integrate complex datasets and communicate insights effectively.

✨Tip Number 4

Don’t forget to apply through our website! It’s the best way to ensure your application gets seen by the right people. Plus, it shows you’re genuinely interested in joining our team at the Discovery Centre.

We think you need these skills to ace Senior Scientist - Genetic Toxicology

High-Throughput Imaging
Genotoxicity Assays
Assay Optimisation
Data Analysis
Data Visualisation
ICH S2(R1) Guidelines
OECD Guidelines
Regulatory Compliance
Project Management
Collaboration
Technical Documentation
Scientific Quality Assurance
Biological Relevance Assessment
Communication Skills

Some tips for your application 🫡

Tailor Your CV: Make sure your CV is tailored to the Senior Scientist role. Highlight your experience in genetic toxicology and any relevant methodologies you've worked with. We want to see how your skills align with our needs!

Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you're passionate about genetic toxicology and how you can contribute to our team. Be sure to mention specific projects or experiences that relate to the role.

Showcase Your Collaborative Spirit: Since we operate in a highly collaborative environment, make sure to highlight your teamwork skills. Share examples of how you've worked with multidisciplinary teams in the past and the impact it had on your projects.

Apply Through Our Website: We encourage you to apply through our website for a smoother application process. It’s the best way for us to receive your application and ensures you don’t miss out on any important updates!

How to prepare for a job interview at AstraZeneca

✨Know Your Science

Make sure you brush up on the latest advancements in genetic toxicology and high-throughput imaging techniques. Be prepared to discuss specific methodologies you've used and how they relate to the role. This shows your passion and expertise in the field.

✨Showcase Collaboration Skills

Since this role involves working closely with multidisciplinary teams, think of examples where you've successfully collaborated with others. Highlight your ability to communicate complex data clearly and how you've contributed to team success in past projects.

✨Prepare for Regulatory Questions

Familiarise yourself with ICH S2(R1) and OECD guidelines, as well as any relevant regulatory expectations. Be ready to discuss how you've applied these in your previous work, as this will demonstrate your understanding of compliance and quality standards.

✨Bring Data to Life

Think about how you've used data analysis and visualisation in your past roles. Prepare to share specific examples of how you've integrated complex datasets to drive decision-making. This will show your analytical skills and your ability to communicate findings effectively.

Senior Scientist - Genetic Toxicology
AstraZeneca

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