At a Glance
- Tasks: Lead innovative mRNA projects and develop next-gen therapeutics in a collaborative lab environment.
- Company: AstraZeneca, a global leader in bio-pharmaceutical innovation.
- Benefits: Competitive salary, excellent benefits, and a commitment to your growth.
- Other info: Join a diverse team dedicated to pushing scientific boundaries.
- Why this job: Make a meaningful impact on global health through cutting-edge science.
- Qualifications: PhD in molecular biology or related field with mRNA expertise.
The predicted salary is between 60000 - 80000 £ per year.
AstraZeneca is a global, innovation-driven BioPharmaceutical business that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious diseases.
Who We Are
RNA Therapy is a team of explorers – always in pursuit of the most effective compounds against new and challenging therapeutic agents. We are pioneering new drug formats, which involves introducing the genetic code for a therapeutic biologic into the patient’s body and enabling their own tissues to produce the therapeutic biologic as required. If you are a lab-based scientist experienced in a range of molecular biology techniques to engineer the next generation mRNA biologic therapeutics for In Vivo Expressed Biologics, then this is an opportunity you don’t want to miss.
As an RNA expert, you will be responsible for executing practical strategies aligned with RNA Therapies and disease therapy requirements, as well as driving innovation within the team through internal collaborations.
What You’ll Do
- Independently define objectives, planning and execution of complex experimental work on mRNA platform development and on mRNA based therapeutic projects.
- Devise mRNA vector design as well as engineering strategies to enhance mRNA production to support ongoing projects.
- Perform general molecular biology techniques to generate mRNA vectors; in vitro transcription reactions and mRNA purification, including HPLC.
- Conduct and troubleshoot cell-based assays following transfection with mRNA to transiently produce functional recombinant protein.
- Analyze data, making detailed observations and interpretation of results.
- Presents findings at internal (intra- and inter-departmental) project team and function meetings.
- Demonstrates strong interpersonal communication by establishing good working relationships with team and department members and others within the company.
Essential Criteria
- Ph. D degree in mRNA therapeutics, molecular biology or life sciences field.
- Experience and in-depth technical knowledge of mRNA generation and optimisation of mRNA platform for production of therapeutic proteins and vaccines.
- Ability to assess immunogenicity/reactogenicity of mRNA; expression and functionality of protein produced from mRNA.
- Experience in experimental method optimisation and troubleshooting experimental processes.
- Good communication, ability to clearly present findings, capable of developing good working relationships with individuals across organisational boundaries and experience working within a team environment.
Desirable Criteria
- Experience of working with, and optimisation of, a self-amplifying RNA platform.
- Bioinformatics or AI experience in the field of mRNA therapeutic development.
- Experience in screening of mRNA therapeutics in translationally relevant cell-based assays.
- Good working knowledge of laboratory automation and sample tracking systems.
Why AstraZeneca? Make a more meaningful impact to patients’ lives around the globe. At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.
Application Deadline Complete your application before July 06th. Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.
mRNA Senior Scientist employer: AstraZeneca
AstraZeneca is an exceptional employer located in the vibrant city of Cambridge, UK, where innovation meets collaboration. With a commitment to diversity and inclusion, employees are empowered to push the boundaries of science while enjoying competitive salaries and excellent benefits. The company fosters a culture of continuous learning and growth, making it an ideal place for mRNA Senior Scientists to thrive and make a meaningful impact on global health.
StudySmarter Expert Advice🤫
We think this is how you could land mRNA Senior Scientist
✨Get Involved in Local Research Communities
Tap into local biotechnology meetups and research forums. These are great places to mingle with industry professionals, share your passion, and even discover unadvertised job openings. It's all about getting your face known in the field!
✨Leverage University Alumni Networks
If you're a recent grad, don’t underestimate the power of your university’s alumni network! Reach out to alumni working in biotechnology to gather tips about job openings at companies like AstraZeneca. You'd be surprised how willing people are to help out a fellow grad!
✨Show Off Your Projects
Curate a portfolio showcasing any research projects or internships you've completed in biotechnology. This tangible evidence of your skills can really impress employers when you chat with them at networking events or interviews. It's about making that killer first impression!
✨Stay Up-to-Date with Industry Trends
Biotech is a fast-paced field, so keeping yourself updated with the latest advancements is crucial. Attend industry conferences, webinars, or workshops to broaden your knowledge and meet potential employers. Plus, it’ll give you fantastic talking points for your interviews at places like AstraZeneca!
We think you need these skills to ace mRNA Senior Scientist
Some tips for your application 🫡
Show Off Your Lab Skills:In the biotechnology field, it's super important to highlight your lab experience in your CV. Be sure to mention specific techniques or instruments you've mastered (think PCR, gel electrophoresis, etc.) and any relevant projects you've worked on. This will show AstraZeneca that you have the hands-on skills they need.
Tailor Your Technical Skills:Make sure to emphasise your technical skills, especially those relevant to the biotechnology sector. Include any software tools or programming languages you've used, like R or Python for data analysis, which could be key for this role at AstraZeneca.
Craft a Compelling Cover Letter:Since this is a full-time role, your cover letter should reflect not only your passion for biotechnology but also your long-term career ambitions. Share why you're excited about the work that AstraZeneca does and how you envision contributing to their goals. This shows that you’re not just looking for any job, but you're genuinely invested in this opportunity.
Include Your Papers and Projects:If you've published any papers or contributed to significant projects, mention them! These documents can boost your application and provide tangible evidence of your expertise in the biotechnology field. Don’t forget to link to any relevant publications or project summaries—this can set you apart from other candidates.
How to prepare for a job interview at AstraZeneca
✨Brush Up on Lab Techniques
Since you're eyeing a full-time gig in biotechnology, make sure you're well-versed in the lab techniques relevant to the role. Be ready to talk about PCR, CRISPR, or any specific methods mentioned in the job description at AstraZeneca. You might even be asked to demonstrate your understanding of these processes.
✨Know Your Bioinformatics Tools
Get comfortable with bioinformatics tools that are commonly used in the industry, like BLAST or Bioconductor. These are key in biotechnology, and having hands-on experience or at least familiarity can set you apart. Prepare to discuss any relevant projects you've worked on, especially if they involved data analysis or genomic research.
✨Show Your Teamwork Skills
Biotech often involves collaboration across multiple disciplines. Be ready to share stories that highlight your teamwork and communication skills, especially in research projects. Think about working with different teams at university or any internships – this is where you can show how well you fit into AstraZeneca's culture.
✨Research Recent Biotech Innovations
Stay updated on the latest trends and breakthroughs in biotechnology. Knowing what's happening in the field can help you engage in more meaningful discussions during your interview. Bring up recent articles or advancements that excite you, especially those related to the work being done at AstraZeneca. This shows your passion for the industry!
