Medical Director, Patient Safety Physician in Luton

Location: 3 days onsite in Luton UK

Are you ready to lead patient safety innovation at the forefront of global healthcare? At AstraZeneca, we're not just developing tomorrow's medicines—we're reimagining how patient safety shapes every breakthrough. As a Medical Director and Patient Safety Physician in our vibrant Luton hub, you'll join a collaborative network of world-class professionals who turn complex challenges into life-changing solutions. Here, your expertise doesn't just protect patients; it drives the strategic decisions that bring hope to millions worldwide. We believe that exceptional patient safety requires exceptional minds working together across continents, combining cutting-edge science with unwavering integrity to ensure every innovation serves humanity's greatest need: safe, effective treatments that transform lives!

Main Duties and Responsibilities:

• Responsible for the Clinical Safety strategy for assigned drug projects and products throughout all stages of development and/or when on the market.
• Implementation and communication of the strategy at the project team/governance level.
• Continued safety assessment, evaluation and risk management of AZ products or product groups in various stages of clinical development and/or the post-marketing setting.
• Consistent communication of safety topics across all regulatory safety documents, e.g. Periodic Benefit Risk Evaluation Reports (PBRERs), Periodic Adverse Drug Experience Reports (PADERs) and Development Safety Update Reports (DSURs).
• Proactively evaluate the clinical implications of safety data from pre-clinical studies, clinical studies, literature to predict/establish the safety profile of compounds in clinical development.
• Involved in all safety surveillance activities, including medical review of individual safety cases, signal detection, evaluation and SERM activities for all products in area of responsibility.
• Medical input and review of periodic reports and renewal documentation submitted to regulatory agencies.
• Patient safety contribution to global regulatory submissions for new products, formulations or indications.

Essential Education, Experience and Skill Requirements:

• Medical degree (e.g. MD, MBBS).
• 2+ years of clinical experience post-registration.
• High level of medical competence, with an ability to balance this with industry standards to achieve business goals.
• 2+ years of Drug Development/Patient Safety experience with clear evidence of delivery.

Preferred Education, Experience and Skills:

• Higher Medical Training in Pharmaceutical Medicine MSc/PhD in scientific field.
• Ability to work across TAs and Functions.
• Experience leading and inspiring Patient Safety colleagues.
• A demonstrated ability to understand epidemiological data.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn’t mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca, patient impact drives every decision: a broad and rapidly evolving Oncology pipeline offers constant exposure to novel mechanisms, complex data and innovative trial designs; cross-functional collaboration with global experts fuels learning; a culture that values courage, curiosity and smart risk-taking empowers decisive action based on science; and continuous development opportunities support long-term growth while contributing directly to transforming cancer care worldwide.

So, what’s next:

If this role matches your expertise and ambition, apply now to help shape the future of patient safety in Oncology.

Please note: we operate a rolling recruitment process and may close this vacancy early if a strong candidate is identified. Early applications are strongly encouraged. Competitive salary and benefits package on offer. The successful candidate will have access to a flexible employee benefits fund, including holiday purchase and flexible time off, pension contributions, Share Save Plans, a performance recognition scheme and a competitive, generous remuneration package.

Date Posted: 24-Apr-2026

Closing Date: 05-Jun-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.