Director, Site Management & Monitoring – UK Oncology in Luton

Location: Luton (onsite 3 days per week)

About AstraZeneca

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious diseases. At AstraZeneca, we are pioneering new frontiers by identifying and treating patients earlier, working towards the aim of eliminating cancer as a cause of death.

The Director Site Management & Monitoring (DSMM) is accountable for successfully delivering their portion of the AZ UK Oncology Clinical Trials portfolio according to agreed resources, budget and timelines aligning with AZ Procedural Documents, international guidelines such as ICH-GCP as well as relevant local regulations. The DSMM is responsible for line managing dedicated group(s) of staff and responsible for planning and utilization of staff resources, assigned budget, objective setting and performance follow-up.

As assigned, the DSMM is accountable for ensuring that study sites are identified, site qualifications performed, set up, initiated, monitored, closed and documentation archived.

Key Responsibilities:

• Leadership of dedicated group, building the team spirit, developing team style and behaviour.
• Ensures adequate resources for the studies assigned.
• Ensures that the workload of direct reports is adequate and responsible for development and performance management of the direct reports according to IDP process.
• Coaches the direct reports on a regular basis, and plans/organises coaching with external providers if needed.
• Prepares salary and bonus proposals for direct reports based on their performance in close collaboration with responsible (Senior) Director, Country Head and local HRBP.
• Contributes to efficient SMM organisation and its functioning at country level by working closely with responsible (Senior) Director, Country Head.
• Oversees successful delivery of UK SMM clinical trials to plan, with speed and quality.
• Contributes to the quality improvement of the local processes and other procedures.
• Provides direction to LSAD/ Local Study Teams on major study commitments including forecasting study timelines, resources, recruitment, study materials and drug supply.
• Ensures close collaboration with local Medical Affairs team.
• Ensures that study activities at country level align with local policies and code of ethics.
• Reviews SQV reports of direct reports in line with AZ SOPs.
• Reviews Accompanied site visits/co-monitoring visits/training visits/QC visits performed to direct reports in line with the local QC plans.
• Performs accompanied site visits according to local QC Plan, supporting ongoing coaching and development.

Requirements:

• Bachelor degree in related field, preferably in life science, or equivalent qualification.
• Significant years of experience in Clinical Trials (CRA / SrCRA / LSAD) or other related fields.
• Proven leadership experience managing and developing teams, including coaching, performance management, and building a strong team culture.
• Experience in study resource planning and workload management to ensure appropriate support for assigned studies.
• Experience delivering clinical study targets at country level, with a focus on timelines, quality, and operational performance.
• Experience contributing to study planning and forecasting, including timelines, recruitment, materials, and drug supply.
• Strong knowledge of the Clinical Study Process and international ICH-GCP guidelines.
• Manage change with a positive approach for self, team and business.
• Excellent organisational, analytical, influencing and negotiation skills.
• Excellent presentation and communication skills, verbal and written.

Desirables:

• Excellent knowledge of the Monitoring Process.
• Good knowledge of ICH GCP plus relevant local and international regulations.
• Ability to learn relevant AZ Therapeutic Areas.
• Ability to look for and champion more efficient and effective methods/processes of delivering quality clinical trials with reduced budget and in less time.

In Office Requirement:

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Competitive salary and benefits package on offer. The successful candidate will have access to a flexible employee benefits fund, including holiday purchase and flexible time off, pension contributions, Share Save Plans, a performance recognition scheme and a competitive, generous remuneration package.

Date Posted: 29-Jul-2026

Closing Date: 12-Aug-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.