Senior Applied AI & ML Engineer in London

Senior Applied AI & ML Engineer in London

London Full-Time 43000 - 83000 £ / year (est.) Home office (partial)
A

At a Glance

  • Tasks: Prototype and build AI systems to enhance clinical trial success and improve patient outcomes.
  • Company: Join Evinova, a pioneering health-tech business within AstraZeneca, transforming clinical trials.
  • Benefits: Competitive salary, hybrid work model, and an inclusive environment with excellent benefits.
  • Other info: Collaborate with experts in a dynamic setting focused on innovation and growth.
  • Why this job: Make a real impact in healthcare by leveraging advanced AI and ML technologies.
  • Qualifications: Ph.D. or equivalent experience in health/life sciences and strong Python development skills.

The predicted salary is between 43000 - 83000 £ per year.

Requirements

  • We are looking for someone with domain knowledge in drug development, clinical trial design, or real-world data (EHR, claims, prescriptions).
  • We require a Ph.

D. or equivalent professional experience in a health or life science field, such as medicine, pharmacy, pharmacology, epidemiology, biostatistics, immunology, neuroscience, translational or clinical research, or bioinformatics.

  • We want previous industry experience building applied ML/AI systems that have shipped as part of a product and driven measurable business impact.
  • We require hands-on work with generative AI, including prompt engineering, context engineering, and multi-agent systems, plus experience with managed endpoints such as Open AI, Anthropic, and AWS Bedrock and open-weight models in the Hugging Face ecosystem.
  • We are looking for knowledge of agentic design patterns and working with LLMs.
  • We expect scientific rigour applied to AI, including the ability to question whether outputs actually make sense.
  • We require experience working with scientific datasets and literature.
  • We need Python development skills.
  • We require experience with Git Hub.
  • We want awareness of working cloud environments.
  • We require the ability to translate complex technical work into clear narratives for both technical and non-technical stakeholders.
  • We value experience sharing knowledge with peers, particularly in the scientific or clinical domain.
  • Desirable: experience with classical ML and NLP methods.
  • Desirable: software craft skills such as testing, observability, documentation, and code review.
  • Desirable: deep experience building secure, compliant RAG pipelines with provenance tracking, including web automation, parsing, and document processing.
  • Desirable: hands-on experience with multi-agent orchestration tools such as Google ADK, Strands Agents, Lang Graph, Crew AI, or equivalents.
  • Desirable: experience with real-world data sources such as EHR, claims, prescriptions, and registries, and their pitfalls.
  • Desirable: effective use of AI-augmented development tools such as Copilot, Cursor, and Claude Code.
  • Desirable: startup-pace experience, including comfort with ambiguity, rapid iteration, and wearing multiple hats.

Responsibilities

  • We prototype and build the systems that make our targets real.
  • We bring scientific and clinical judgement to work with stakeholders to develop ML and agentic systems that drive transparent and actionable recommendations.
  • We integrate multi-source data, including historical trials and scientific datasets, into production systems.
  • We improve the process of designing clinical trials and increase their probability of success.
  • We work with experienced ML and platform engineers while developing our engineering craft.
  • We translate complex technical work into clear narratives for both technical and non-technical stakeholders.
  • We share knowledge with peers, particularly within the scientific and clinical domain.

Technologies

  • AI
  • AWS
  • Claude Code
  • Cloud
  • Copilot
  • Cursor
  • Git Hub
  • Python
  • RAG
  • Web
  • Machine Learning

More

We are Evinova, a new health-tech business within the Astra Zeneca Group, using advanced algorithms and Gen AI to boost clinical trial success, cut development time, and reduce study costs.

We draw on Astra Zenecas experience developing novel therapeutics and aim to improve the design and delivery of clinical trials for better patient experiences and outcomes.

We are building a new kind of health tech business that resets expectations of what a biopharmaceutical company can be, opening new ways to work and bringing unexpected teams together.

This is a full-time Senior Applied AI & ML Engineer role based in St Pancras, London, with a hybrid schedule of three days per week onsite and an excellent benefits package.

We work in an inclusive and equitable environment and offer reasonable adjustments or accommodations during recruitment.

  • last updated 36 week of 2026
  • #J-18808-Ljbffr

Senior Applied AI & ML Engineer in London employer: AstraZeneca

AstraZeneca is an exceptional employer, offering a dynamic work environment in Cambridge where innovation meets collaboration. Employees benefit from a culture that values entrepreneurial thinking and scientific excellence, alongside opportunities for professional growth through mentorship and cross-functional projects. With a commitment to diversity and inclusion, AstraZeneca fosters a supportive atmosphere that empowers individuals to make meaningful contributions to life-changing medicines.

A

Contact Details:

AstraZeneca Recruitment Team

StudySmarter Expert Advice🤫

We think this is how you could land Senior Applied AI & ML Engineer in London

Join Local Tech Meetups

Get out there and mingle with fellow developers by joining local tech meetups. It’s a fantastic way to meet people who might be working at AstraZeneca or know someone who does. Plus, you can pick up some trendy tech skills and trends while you're at it!

Contribute to Open Source Projects

Show off your coding chops by jumping into open-source projects. Not only does this give you practical experience, but it also gets you noticed in the dev community. You'll create a killer portfolio that speaks volumes about your skills to AstraZeneca.

Tap into Online Developer Communities

Don’t underestimate the power of online developer communities like GitHub, Stack Overflow, and even Reddit. Participate in discussions, share your projects, and build your visibility. We can often find opportunities through these channels that can lead to a full-time gig at companies like AstraZeneca.

Explore Job Boards Specifically for Tech Roles

Keep your eyes peeled on job boards that focus on tech roles. Sites like TechCareers or Stack Overflow Jobs can often have listings for companies like AstraZeneca that might not show up on broader job sites. Make it a habit to check these regularly, and don’t hesitate to apply directly through our website!

We think you need these skills to ace Senior Applied AI & ML Engineer in London

Domain Knowledge in Drug Development
Clinical Trial Design
Real-World Data (EHR, Claims, Prescriptions)
Ph.D. or Equivalent Professional Experience in Health or Life Science
Applied ML/AI Systems Development
Generative AI (Prompt Engineering, Context Engineering, Multi-Agent Systems)
Experience with Managed Endpoints (OpenAI, Anthropic, AWS Bedrock)

Some tips for your application 🫡

Show off your coding skills:When applying for a software engineering role, it's super important to showcase your coding skills. Make sure your CV includes your tech stack, any relevant programming languages you’re comfortable with, and examples of projects you've worked on. If you have a GitHub profile, link it up! We love to see code in action.

Tailor your portfolio:For a full-time role, we’d expect to see some solid examples of your work in your portfolio. Make sure to include at least two or three projects that highlight your problem-solving skills and your ability to work with different technologies. Focus on the projects that are most relevant to the position at AstraZeneca.

Craft a killer cover letter:Your cover letter is your chance to stand out—make it personal! Explain why you want to work at AstraZeneca and how your skills align with the role. Show us your passion for software development. We dig enthusiastic candidates who understand the value of collaboration and continuous learning!

Be clear and concise:When it comes to writing your CV and cover letter, clarity is key. Avoid jargon that could confuse us and stick to simple, direct language. Highlight your achievements with quantifiable results where possible, and keep everything easy to read. A well-organised application goes a long way!

How to prepare for a job interview at AstraZeneca

Brush Up on Your Coding Skills

For a full-time software engineering role, it's crucial that we stay sharp with our coding abilities. Expect technical questions that might involve solving problems on the spot or discussing algorithms. Practise on platforms like LeetCode or HackerRank to get comfortable with the types of questions that often come up.

Know Your Tools and Frameworks

Make sure we’re well-acquainted with the tools and technologies listed in the job description. Familiarise ourselves with any specific frameworks or programming languages mentioned. If AstraZeneca uses React or Node.js, for instance, be ready to discuss how we’ve used them in previous projects or coursework.

Showcase Your Projects

Bring along a portfolio that highlights our best work. This could be code samples, GitHub repositories, or any side projects we’ve built. Make sure we can talk through our thought process for each project, especially the challenges we faced and how we solved them—this shows our problem-solving skills in action.

Prepare for Behavioural Questions

While technical skills are key, full-time positions also require cultural fit. Be ready to discuss our previous experiences and how we handle teamwork, conflict, and deadlines. Brush up on the STAR method—Situation, Task, Action, Result—to clearly articulate our past experiences when discussing how we've contributed to a team.