Senior Tax Manager – Tax Reporting and UK Tax Compliance in Cambridge

Location: Cambridge, London or Luton UK

About AstraZeneca

AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. At AstraZeneca, we're proud to have a unique workplace culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives - you are made to feel valued, energised and rewarded for your ideas and creativity.

Our dynamic in-house Global Tax Operations team are ready for a Senior Tax Manager to join them. If you are a qualified accountant with significant UK direct tax and tax reporting experience, this is an excellent opportunity to experience and influence UK tax compliance and accounting in a FTSE 100.

Reporting to Tax Associate Directors and supported by our Tax Delivery Team, you will help our team, headed by a Senior Tax Director, drive the delivery of our UK direct tax compliance and support with group tax reporting processes. You will be a diligent and technically strong individual with a solid commercial competence and a genuine passion for understanding AstraZeneca's business.

Key Responsibilities:

• Support with preparation and review of UK corporation tax computations and other UK obligations, including considerable claims e.g. patent box and capital allowances.
• Delegate and review analysis to support tax activities prepared by finance colleagues.
• Support with operation of wider tax governance processes, including obligations under the Corporate Criminal Offence legislation and Senior Accounting Officer regime.
• Review and advise on UK tax issues including Corporate Interest Restriction rules, Controlled Foreign Companies risk assessments.
• Stay ahead of changes in UK tax legislation, understand implications and design changes in processes.
• Liaise with the various accounting teams within the UK to ensure accurate and timely delivery of information required for tax reporting, the tax computations and audit queries.
• Prepare responses to HMRC audit queries and participate in meetings and negotiations with HMRC, as required.
• Provide day-to-day tax advice to the UK business and assess implications of projects on UK compliance and tax accounting.
• Prepare quarterly and year-end tax provisions for UK reporting and Group consolidation, ensuring compliance with Sarbanes-Oxley processes and collaborating closely with statutory auditors.
• Input into group planning and forecasting cycles.
• Help drive process efficiencies through use of automation and AI.

Requirements:

• Qualified (ACCA, ACA, CTA) tax professional with good accounting skills.
• Significant experience in UK corporate tax compliance and reporting.
• Ability to monitor changes in UK tax legislation, assess business impact, and translate those changes into updated processes or controls.
• Experience contributing to group planning, budgeting, and forecasting cycles from a tax perspective.
• Strong analytical and research skills, and ability to utilise technology effectively to operate tax processes.
• Ability to lead and progress numerous actions in a coordinated and organised manner.
• Efficient process management and delegation skills.
• Ability to work to tight deadlines.
• Interest or experience in automation and AI-enabled process improvement.

In Office Requirement:

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Competitive salary and benefits package on offer! The successful candidate will have access to a flexible employee benefits fund, including holiday purchase and flexible time off, pension contributions, Share Save Plans, a performance recognition scheme and a competitive, generous remuneration package.

Date Posted: 23-Jul-2026

Closing Date: 05-Aug-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.