At a Glance
- Tasks: Develop innovative models and assays to tackle obesity and metabolic diseases.
- Company: Join AstraZeneca, a leader in inclusive and equitable scientific research.
- Benefits: Competitive salary, excellent benefits, and opportunities for professional growth.
- Other info: Dynamic environment with a focus on cutting-edge technologies and AI in research.
- Why this job: Make a real impact in metabolic research and collaborate with top scientists.
- Qualifications: PhD in relevant field with hands-on experience in neuroscience and metabolism.
The predicted salary is between 50000 - 65000 € per year.
Location: Cambridge, UK
Salary: Competitive Salary & Excellent Company Benefits
Main duties and responsibilities:
- Develop and validate in vitro, advanced cell models, ex vivo models, and assays for studying obesity and assessing signalling endpoints for multiple target classes.
- Design and perform experiments to evaluate the efficacy and mechanism of novel drug candidates.
- Analyse and interpret experimental data, and present research findings to project teams, external partners and at scientific conferences.
- Collaborate with cross-functional teams to support drug discovery and development projects.
- Stay up to date with the latest scientific advancements in the field of metabolic disease/obesity.
- Identify and develop new target ideas, implement new models/assays and apply latest technologies relevant to obesity and metabolic disease research areas.
- Prepare scientific publications and documents for patents and regulatory submissions.
Essential for the role:
- PhD with postdoctoral training in neuroscience, physiology, pharmacology or another relevant field.
- Deep understanding of CNS pathways and signal transduction mechanisms that govern body weight control with a proven track record in the metabolic neuroscience field.
- Demonstrable hands-on experience working with a variety of in vitro cell-based and ex-vivo methods and technologies for researching neurocircuits of appetite regulation.
- Proven ability to develop and optimise new models and protocols, troubleshoot, interpret experimental results/data, and maintain accurate, high-quality records.
- Proficiency in data analysis and interpretation using relevant software and statistical tools.
- Excellent written and verbal communication skills with an ability to clearly articulate complex scientific concepts, and an ability to quickly learn and embrace new technologies.
- Experience and/or fresh ideas for leveraging AI in obesity research.
- Strong publication record, exemplified by first-author publications in high-impact journals.
Desirable requirements:
- Experience in leading CNS model development suitable for high-throughput target screening platforms.
- Experience in molecular biology approaches and vector design for interrogating appetite regulatory pathways and mechanisms.
- HO PIL A/B/C license holder with experience in stereotactic manipulations, analysis of feeding behaviour, and nausea/emesis.
- Experience working in the pharmaceutical industry, particularly in drug discovery and development.
Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best.
Senior Scientist or Associate Principal Scientist Metabolism Team in Cambridge employer: AstraZeneca
AstraZeneca is an exceptional employer located in the vibrant city of Cambridge, UK, offering a dynamic work culture that fosters innovation and collaboration within the Metabolism team. Employees benefit from competitive salaries, comprehensive company benefits, and ample opportunities for professional growth, all while contributing to groundbreaking research in metabolic diseases. The inclusive environment encourages diverse perspectives, ensuring that every team member feels valued and empowered to make a meaningful impact in drug discovery.
StudySmarter Expert Advice🤫
We think this is how you could land Senior Scientist or Associate Principal Scientist Metabolism Team in Cambridge
✨Network Like a Pro
Get out there and connect with folks in the industry! Attend conferences, seminars, or even local meetups related to metabolic research. We can’t stress enough how valuable personal connections can be when it comes to landing that dream job.
✨Show Off Your Skills
When you get the chance to chat with potential employers, make sure to highlight your hands-on experience with in vitro and ex vivo methods. We want to see you confidently discussing your past projects and how they relate to the role you're after!
✨Stay Current
Keep yourself updated on the latest advancements in metabolic disease research. We recommend reading recent publications and following key researchers in the field. This knowledge will not only impress interviewers but also show your genuine passion for the subject.
✨Apply Through Our Website
Don’t forget to apply directly through our website! It’s the best way to ensure your application gets seen by the right people. Plus, we love seeing candidates who take that extra step to engage with us directly.
We think you need these skills to ace Senior Scientist or Associate Principal Scientist Metabolism Team in Cambridge
Some tips for your application 🫡
Tailor Your CV:Make sure your CV is tailored to the role of Senior Scientist or Associate Principal Scientist. Highlight your experience in metabolic neuroscience and any relevant projects you've worked on. We want to see how your skills align with our mission!
Craft a Compelling Cover Letter:Your cover letter is your chance to shine! Use it to explain why you're passionate about obesity research and how your background makes you a perfect fit for our Metabolism team. Keep it engaging and personal – we love to see your personality!
Showcase Your Research Skills:In your application, be sure to highlight your hands-on experience with in vitro and ex vivo methods. Discuss any innovative models or assays you've developed, as well as your proficiency in data analysis. We’re keen to see your scientific prowess!
Apply Through Our Website:We encourage you to apply directly through our website. It’s the best way to ensure your application gets into the right hands. Plus, you’ll find all the details you need about the role and our company culture there!
How to prepare for a job interview at AstraZeneca
✨Know Your Science
Make sure you brush up on the latest advancements in metabolic disease and obesity research. Be ready to discuss your previous work, especially any hands-on experience with in vitro and ex vivo models. This will show that you’re not just knowledgeable but also passionate about the field.
✨Prepare for Technical Questions
Expect to dive deep into your understanding of CNS pathways and signal transduction mechanisms. Prepare to explain complex concepts clearly, as communication is key. Practise articulating your thought process when troubleshooting experimental results or developing new models.
✨Showcase Your Collaboration Skills
Since this role involves working with cross-functional teams, be ready to share examples of how you've successfully collaborated in the past. Highlight any experiences where you supported drug discovery projects or worked alongside different departments to achieve a common goal.
✨Bring Fresh Ideas
With the mention of leveraging AI in obesity research, think about innovative ideas you could bring to the table. Prepare to discuss how you might implement new technologies or methodologies in your research, showing that you’re forward-thinking and adaptable.
