Pathology Manager in Translational Pathology, Oncology in Cambridge

Job Title: Pathology Manager in Translational Pathology Oncology

Location: Cambridge

Salary: Competitive

Introduction to role

Are you ready to make a difference at AstraZeneca? We are seeking a Pathology and Sample Manager to join our Translational Pathology group within the Oncology R&D Cancer Biomarker and Translational Medicine divisions. This is your chance to be at the forefront of translational science evolution for our global oncology group. You\’ll have the opportunity to impact an industry‑leading portfolio from early clinical development of novel therapeutics to post‑marketing opportunities supporting approved targeted therapies. Are you up for the challenge?

Accountabilities

Support the operation of the Translational Pathology UK group by assisting leadership with delivery of cancer biomarker portfolio goals.

Coordinate with leadership team to manage contract workers including contract pathologists.

Assist implementation and proper use of the department\’s laboratory information management system.

Draft and update standard operating procedures, work instructions, scoring sheets.

Maintain up-to-date laboratory staff and contractor training and proficiency records.

Manage and ensure the portfolio management system (Smartsheet) is current.

Review department purchasing and accounts to ensure team remains within annual budget allocation.

Manage cross‑charging activities across the portfolio.

Design and support improvements in scientific or operational approaches and technologies to enhance project quality, efficiency and effectiveness.

Contribute to strategic planning and preparation of proposals and business cases.

Serve as a resource by sharing expertise within and beyond Translational Medicine and Cancer Biomarker Development departments.

Collaborate with other functions ensuring effective communication.

Ensure compliance with Good Clinical Practice, Safety, Health and Environment standards and all relevant internal AstraZeneca standards and external regulations.

Generate working instructions and SOPs in line with GCP standards.

Act as sample owner for commercial human biological tissue samples under the team’s remit.

Procure high‑quality human biological tissue and manage storage and usage, building a repository to support our pipeline.

Essential Skills / Experience

• PhD with exposure in a relevant field.
• PMP certification or equivalent project management experience/training.
• Strong previous pharmaceutical industry experience.
• Experience in histology techniques or working with pathologists.
• Experience in project management including using project management software such as Asana or Smartsheet with a demonstrated track record of success in delivering projects on‑time and on‑budget.
• Strong organizational skills including good time‑management skills. Must be highly organized and able to work independently on multiple tasks in a fast‑paced environment.
• Takes appropriate initiative and accountability including proactively prioritizing work in alignment with business requirements.
• Experience handling the outsourcing and management of outsourced projects.
• Experienced in using MS Office Suite especially PowerPoint, Word and Excel.
• Strong interpersonal and communication skills.
• Familiarity with human tissue tracking software or LIMS.

Desirable Skills / Experience

• Knowledge of immunohistochemistry (brightfield or fluorescence) microscopy and carrying out biomarker quantification studies using digital image analysis software.
• Knowledge in one or more AZ portfolio areas: tumour drivers and resistance, DNA damage response (DDR), immuno‑oncology (IO), antibody drug conjugates (ADC) and epigenetics.
• Some experience or exposure to microscopy and digital image analysis with software such as HALO or Visiopharm.
• Functional knowledge of FDA Code of Federal Regulations Title 21 Parts; Good Clinical Practice for Laboratories; any AZ processes and policies involved in relation to the acquisition, receipt, storage, use and disposal of human tissue samples.
• Familiarity with cell culture and interpreting genomics and RNA sequencing data.

When we put unexpected teams in the same room we unleash bold thinking with the power to inspire life‑changing work. That’s why we work on average a minimum of three days per week from the office, but we’re flexible, balancing expectations with individual flexibility.

AstraZeneca is where courage meets curiosity! With an ambition to eliminate cancer as a cause of death we are driven by patient outcomes. Our innovative pipeline is backed by investment aiming to deliver new molecular entities by 2025. We are pioneers of collaborative research uniting academia and industry to expedite research in hard‑to‑treat cancers. Here you can build a rewarding career as part of a team committed to improving millions of lives.

What’s Next

We welcome your application no later than 19th November 2025.

Follow AstraZeneca on LinkedIn, Facebook and Instagram for updates and apply now to join us on this exciting journey!

Date Posted 11-Nov-2025

Closing Date 19-Nov-2025

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion starting with our recruitment process. We welcome and consider applications from all qualified candidates regardless of characteristics. We offer reasonable adjustments and accommodations to help all candidates perform at their best.

Vacancy: 1, Employment Type: Full‑time