Technical Lead (HPC Infrastructure) - SCP in Newtown
Technical Lead (HPC Infrastructure) - SCP

Technical Lead (HPC Infrastructure) - SCP in Newtown

Newtown Full-Time 54000 - 84000 £ / year (est.) No home office possible
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At a Glance

  • Tasks: Lead high-performance computing infrastructure to accelerate scientific discovery and innovation.
  • Company: Join a pioneering organisation dedicated to life-changing medicines and cutting-edge technology.
  • Benefits: Competitive salary, flexible working options, and opportunities for professional growth.
  • Why this job: Make a real impact in science while leading a dynamic and innovative team.
  • Qualifications: Experience in HPC, cloud services, and mentoring engineering teams.
  • Other info: Collaborative environment with a focus on continuous improvement and technological advancement.

The predicted salary is between 54000 - 84000 £ per year.

Are you ready to lead high-performance computing infrastructure that accelerates discovery and brings life-changing medicines to patients faster? This is your opportunity to set the direction for a mission-critical platform that underpins data science, computational biology and AI/ML workloads across the enterprise. You will steer a modern HPC environment spanning on-premises and cloud, enabling scientists to run at scale and speed while maintaining reliability and cost efficiency. Do you thrive at the intersection of engineering rigor and scientific impact, where your decisions unlock faster insights and smarter experimentation? In this hands-on leadership role, you will be empowered to take ownership, challenge the status quo and orchestrate new possibilities—partnering closely with researchers, pushing boundaries in hackathons and ensuring our platform evolves with the demands of cutting-edge science.

Responsibilities

  • Define and own the strategic roadmap for the HPC infrastructure, aligning capacity, architecture and capabilities to scientific priorities and business outcomes.
  • Drive continuous improvement of platform stability, efficiency and performance; set clear metrics and ensure reliability for large-scale workloads and time-critical studies.
  • Lead delivery across on-premises and cloud environments, optimizing for speed, scalability and cost while ensuring seamless user experience.
  • Work with scientific users to understand their needs and translate them into robust solutions, enabling faster models, simulations and analyses.
  • Scan the horizon to identify emerging technologies that keep the platform innovative and competitive, and guide timely adoption.
  • Prioritize the team's work based on scientific impact, balancing quick wins with longer-term investments to maximize value.
  • Mentor and coach engineers, build capabilities and foster a high-performance, collaborative engineering culture.
  • Investigate and resolve complex operational incidents, lead root-cause analysis and implement preventative improvements that strengthen the platform.

Essential Skills/Experience

  • Defining the roadmap for the platform's HPC infrastructure.
  • Drive continuous improvement of the stability and efficiency of the platform.
  • Ensuring delivery of team objectives, both on-premises and in the cloud.
  • Working with scientific users to understand their needs, and develop solutions.
  • Horizon scanning, identifying the future technologies needed to stay innovative.
  • Prioritising the work backlog for the team according to scientific needs.
  • Mentoring and coaching engineers.
  • Investigating and resolving complex operational incidents.
  • Experience with HPC schedulers and workload managers (e.g., Slurm, PBS, Grid Engine) and job orchestration at scale.
  • Hands-on knowledge of cloud-based HPC services and architectures (e.g., Azure, AWS, GCP), hybrid networking and cost optimization.
  • Containerization and orchestration for scientific workloads (e.g., Docker, Singularity, Kubernetes).
  • Infrastructure as Code and automation (e.g., Terraform, Ansible, CI/CD), plus strong scripting skills in Python and Bash.
  • Performance tuning and profiling of compute and storage, including GPUs, accelerators and parallel filesystems (e.g., Lustre, Spectrum Scale).
  • Workflow management tools (e.g., Nextflow, Snakemake) and data pipelines supporting AI/ML and bioinformatics.
  • Robust approach to reliability engineering, observability and security/compliance for sensitive research data.
  • Proven stakeholder engagement across research, engineering and product teams, with the ability to balance speed, quality and sustainability.

Technical Lead (HPC Infrastructure) - SCP in Newtown employer: AstraZeneca UK Limited

Join a pioneering organisation that is at the forefront of high-performance computing, where your leadership will directly contribute to accelerating scientific discovery and improving patient outcomes. With a strong emphasis on collaboration, continuous improvement, and employee development, you will thrive in a dynamic work culture that values innovation and empowers you to challenge the status quo. Located in a vibrant area, this role offers unique opportunities for professional growth and the chance to work alongside leading researchers in a mission-driven environment.
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Contact Detail:

AstraZeneca UK Limited Recruiting Team

StudySmarter Expert Advice 🤫

We think this is how you could land Technical Lead (HPC Infrastructure) - SCP in Newtown

✨Tip Number 1

Network like a pro! Get out there and connect with folks in the industry. Attend meetups, conferences, or even online webinars. The more people you know, the better your chances of landing that dream job.

✨Tip Number 2

Show off your skills! Create a portfolio or GitHub repository showcasing your projects and achievements. This is your chance to demonstrate your expertise in HPC infrastructure and make a lasting impression on potential employers.

✨Tip Number 3

Prepare for interviews by practising common technical questions and scenarios related to HPC. We recommend doing mock interviews with friends or using online platforms to get comfortable with the process and boost your confidence.

✨Tip Number 4

Don’t forget to apply through our website! We’re always on the lookout for talented individuals who can help us push boundaries in high-performance computing. Your next big opportunity could be just a click away!

We think you need these skills to ace Technical Lead (HPC Infrastructure) - SCP in Newtown

HPC Infrastructure Management
Cloud Computing (Azure, AWS, GCP)
HPC Schedulers and Workload Managers (Slurm, PBS, Grid Engine)
Containerization (Docker, Singularity, Kubernetes)
Infrastructure as Code (Terraform, Ansible)
CI/CD Automation
Scripting (Python, Bash)
Performance Tuning and Profiling
Workflow Management Tools (Nextflow, Snakemake)
Data Pipeline Development for AI/ML and Bioinformatics
Reliability Engineering
Observability and Security Compliance
Stakeholder Engagement
Mentoring and Coaching

Some tips for your application 🫡

Tailor Your Application: Make sure to customise your CV and cover letter to highlight your experience with HPC infrastructure and cloud services. We want to see how your skills align with our mission to accelerate discovery in life sciences.

Showcase Your Leadership Skills: In your application, don’t shy away from sharing examples of how you've led teams or projects. We’re looking for someone who can mentor and inspire others, so let us know how you’ve done that in the past!

Highlight Technical Expertise: Be specific about your hands-on experience with technologies like Slurm, Docker, and Terraform. We love seeing candidates who can demonstrate their technical prowess and how it can benefit our HPC platform.

Apply Through Our Website: We encourage you to submit your application through our website. It’s the best way for us to keep track of your application and ensure it gets the attention it deserves. Plus, it’s super easy!

How to prepare for a job interview at AstraZeneca UK Limited

✨Know Your HPC Inside Out

Make sure you brush up on your knowledge of high-performance computing infrastructure. Be ready to discuss specific technologies like Slurm, AWS, and Kubernetes, and how they relate to the role. Showing that you understand both the technical and operational aspects will impress the interviewers.

✨Showcase Your Leadership Skills

As a Technical Lead, you'll need to demonstrate your ability to mentor and guide a team. Prepare examples of how you've successfully led projects or teams in the past, focusing on your approach to fostering collaboration and driving results. This will highlight your readiness for a hands-on leadership role.

✨Understand the Scientific Impact

Familiarise yourself with the scientific goals of the company and how HPC can accelerate research. Be prepared to discuss how you would translate scientific needs into robust solutions. This shows that you’re not just technically savvy but also aligned with the mission of bringing life-changing medicines to patients.

✨Prepare for Problem-Solving Scenarios

Expect to tackle hypothetical scenarios related to operational incidents or performance tuning during the interview. Think through your problem-solving process and be ready to articulate how you would investigate and resolve complex issues. This will demonstrate your analytical skills and readiness to handle real-world challenges.

Technical Lead (HPC Infrastructure) - SCP in Newtown
AstraZeneca UK Limited
Location: Newtown

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