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- Tasks: Lead the development and governance of modelling strategies in drug development.
- Company: Join AstraZeneca, a global leader in biopharmaceutical innovation.
- Benefits: Enjoy a competitive salary, flexible benefits, and generous time off.
- Why this job: Make a real impact in advancing drug development with cutting-edge modelling technologies.
- Qualifications: PhD in relevant fields and extensive experience in process modelling.
- Other info: Collaborative environment with opportunities for professional growth and leadership.
The predicted salary is between 72000 - 108000 £ per year.
AstraZeneca's Digital Science team within Pharmaceutical Technology & Development (PT&D) is committed to advancing innovation and digital excellence in drug development and manufacturing. The Director, Model Governance will lead the development, implementation, and improvement of AstraZeneca's modelling strategy, ensuring robust governance of computational models across the organization. In this role you will be responsible for building and sustaining modelling standards and aligning new computational technologies with PT&D's broader scientific and operational objectives. You will collaborate across functions, drive adoption of governance standards, be responsible for the integration of new modelling and simulation tools, and represent AstraZeneca's interests within the global scientific community.
Responsibilities
- You will implement, adapt and lead frameworks for model governance including documentation, coding, verification.
- This includes designing processes for model development, coding, documentation, verification, validation, and lifecycle oversight, in alignment with global best practices and regulatory expectations.
- You will collaborate with internal and external collaborators to ensure governance protocols are well understood and embraced, delivering training, infrastructure, and change management support throughout PT&D.
- In this position, you will evaluate and guide the integration of emerging modelling and simulation technologies into PT&D's digital ecosystem, ensuring guidelines are in place to enable integration from a governance perspective.
- Resource stewardship is a central aspect, with responsibility for handling licenses, computing infrastructure, and data storage.
- You will provide leadership to project teams, enabling effective, compliant, and impactful use of models in a broad range of drug development and manufacturing projects.
- Active engagement with regulatory networks and scientific associations will be expected, supporting AstraZeneca's position as a leader in model governance and innovative modelling solutions.
Qualifications
- PhD in chemical engineering, physics, mathematics, or a related subject area.
- Extensive experience in process modelling, simulation, and model lifecycle management within a regulated scientific or pharmaceutical environment.
- Deep understanding and experience across a broad spectrum of modelling types and analysis tools, including mechanistic modelling, data-driven approaches, live digital twins and emerging AI technologies.
- Ability to design and implement enterprise-scale model governance frameworks for quality, compliance, and traceability.
- Broad understanding of global regulatory expectations and best practices in modelling governance.
- Proficiency with computational modelling and simulation software such as ANSYS Fluent, Aspen, gPROMS, Python and MATLAB.
- Ability to develop and deliver training programs, lead change management, and collaborate across business functions.
- Excellent communication and leadership skills for stakeholder engagement and external representation.
- Experience integrating new modelling technologies within complex organisational environments.
Desirables
- Experience delivering large-scale digital platforms for modelling and simulation.
- Participation in scientific or regulatory networks and external forums.
- Track record of scientific publication or impactful research contributions.
- Experience leading digital transformation and technical innovation.
About AstraZeneca
AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical companies. At AstraZeneca, we are pioneering new frontiers by identifying and treating patients earlier, working towards the aim of eliminating cancer as a cause of death.
Benefits
Competitive salary and benefits package on offer! The successful candidate will have access to a flexible employee benefits fund, including holiday purchase and flexible time off, pension contributions, Share Save Plans, a performance recognition scheme and a competitive, generous remuneration package.
Director, Model Governance in Macclesfield employer: AstraZeneca UK Limited
Contact Detail:
AstraZeneca UK Limited Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Director, Model Governance in Macclesfield
✨Tip Number 1
Network like a pro! Reach out to people in the industry, especially those at AstraZeneca. Use LinkedIn to connect and engage with them. A friendly message can go a long way in getting your foot in the door.
✨Tip Number 2
Prepare for interviews by researching AstraZeneca's recent projects and innovations. Show us that you’re not just interested in the role but also in how you can contribute to their mission of advancing drug development.
✨Tip Number 3
Practice your pitch! Be ready to explain how your experience aligns with the Director, Model Governance role. Highlight your skills in model governance and collaboration, and don’t forget to mention any relevant technologies you’ve worked with.
✨Tip Number 4
Apply through our website! It’s the best way to ensure your application gets noticed. Plus, it shows us that you’re genuinely interested in being part of the AstraZeneca team.
We think you need these skills to ace Director, Model Governance in Macclesfield
Some tips for your application 🫡
Tailor Your CV: Make sure your CV reflects the skills and experiences that align with the Director, Model Governance role. Highlight your expertise in model governance and any relevant technologies you've worked with. We want to see how you can bring value to our team!
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to tell us why you're passionate about model governance and how your background makes you the perfect fit for AstraZeneca. Be sure to mention any collaborative projects or leadership experiences that showcase your skills.
Showcase Your Technical Skills: Since this role involves a lot of technical know-how, don’t shy away from listing your proficiency with tools like ANSYS Fluent, Python, or MATLAB. We love seeing candidates who are comfortable with emerging technologies and can integrate them into our processes.
Apply Through Our Website: We encourage you to apply directly through our website for the best chance of getting noticed. It’s the easiest way for us to keep track of your application and ensure it reaches the right people. Plus, it shows you’re serious about joining our team!
How to prepare for a job interview at AstraZeneca UK Limited
✨Know Your Models Inside Out
Make sure you have a solid grasp of the various modelling types and analysis tools mentioned in the job description. Be prepared to discuss your experience with mechanistic modelling, data-driven approaches, and any emerging AI technologies you've worked with. This will show that you're not just familiar with the concepts but can also apply them effectively.
✨Demonstrate Governance Expertise
Since the role focuses heavily on model governance, come ready to share examples of frameworks you've designed or implemented in the past. Discuss how you ensured compliance and quality in your previous roles, and be specific about the challenges you faced and how you overcame them.
✨Showcase Collaboration Skills
This position requires collaboration across various functions, so think of instances where you've successfully worked with different teams. Prepare to talk about how you’ve driven adoption of standards and provided training or change management support. Highlight your communication skills and how they helped in stakeholder engagement.
✨Stay Updated on Regulatory Trends
Familiarise yourself with current global regulatory expectations and best practices in modelling governance. Being able to discuss recent developments or changes in regulations will demonstrate your commitment to staying informed and your ability to lead AstraZeneca's interests within the scientific community.
