At a Glance
- Tasks: Lead health economic content for national HTA submissions and develop cost-utility models.
- Company: Join AstraZeneca, a leader in biopharmaceuticals with a commitment to innovation.
- Benefits: Flexible working, competitive salary, and opportunities for professional growth.
- Other info: Collaborative environment focused on diversity and lifelong learning.
- Why this job: Make a real impact on patient access to life-changing medicines.
- Qualifications: Postgraduate in health economics and 3+ years of HTA experience required.
The predicted salary is between 63634 - 77774 £ per year.
- Health Economics Manager, CVRM (9-months Secondment/FTC)
- London, Pancras Square
- Introduction to the role
Do you have expertise in and passion for access submissions?
Would you like to apply your expertise in a company that follows the science and turns ideas into life changing medicines?
Then Astra Zeneca might be the one for you!
As a Health Economics Manager on this 9-months Secondment opportunity in the Biopharmaceutical Business Unit (CVRM: Cardiovascular, Renal & Metabolic), you will lead the delivery of health economic content for national Health Technology Assessment (HTA) submissions.
This is a hands‑on modelling role: you will build, adapt, and own the cost‑utility and budget impact models that convey the value of Astra Zeneca medicines and help secure national-level patient access.
Reporting to the Head of Market Access, CVRM, you will partner with the UK Market Access function, the Medical Directorate, Brand Marketing teams (as well as broader UK‑based cross functional teams), and the Global Health Economics & Payer Evidence team.
- Accountabilities
- Develop, tailor, and deliver health economic analyses for health technology appraisals (75%)
- Cost-Utility and
- Budget
- Impact
Modelling: Take a hands‑on approach to tailoring final deliverables to UK HTA needs, including developing budget impact analyses and adapting cost‑utility models in Microsoft Excel.
- Global HEOR Collaboration: Work with the global HEOR function to shape cost‑utility analysis models, systematic literature reviews, network meta‑analyses, and other payer‑related materials for HTA.
- Strategic Input: Provide strategic input into pricing strategy, evidence needs, and related decisions.
- Prior Appraisal Research: Research prior appraisals to understand relevant considerations.
- Submissions: Write the cost‑effectiveness sections for submissions to NICE, SMC, and AWMSG, working collaboratively with UK Market Access colleagues and the Medical team.
- Technical Responses: Provide high‑quality responses to technical assessor questions, including model‑related queries.
- Committee Representation: Represent Astra Zeneca to a high standard at appraisal committee meetings.
- Outsourcing: Manage the outsourcing of some aspects, as needed. Ensure deliverables are of high quality.
- Develop early cost‑effectiveness analyses for future brands and indications (20%)
- Early
Modelling: Build early cost‑effectiveness models based on the target product profile to inform national market access feasibility assessments, support the internal forecasting process, and feed into global‑led consultations.
- Prior Appraisal Research: Research prior appraisals to understand relevant considerations.
- Business partnering on priority brands (5%)
- Brand and Therapy Area Knowledge: Develop strong brand and therapy area knowledge to support Brand Marketing Teams, taking the time to understand their needs.
- Cross‑Functional Planning: Contribute to strategic and operational planning within cross‑functional teams.
- Performance indicators: HTA outcomes versus expectations, feedback from internal customers, and performance versus goals.
Essential Requirements
- Modelling Expertise (Key Requirement): Proven ability to develop cost‑utility analysis and budget impact models in Microsoft Excel.
- VBA: Working knowledge (or above) of Microsoft VBA.
- Education: Postgraduate qualification in health economics.
- HTA Experience: 3+ years of experience developing HE content for HTA submissions, in either a HEOR agency or the pharmaceutical industry.
- Communication: Excellent interpersonal and communication skills, including strong written skills.
- Delivery and Collaboration: Demonstrable record of collaborative working and personal delivery to agreed timelines.
- Prioritization: Ability to prioritize effectively based on business need.
- Capability Building: Experience training non-Health Economists in the effective delivery of HE outputs.
Desirable Requirements
- Education: First degree in economics, life sciences, mathematics, or similar.
- Supplier Management: Experience managing external suppliers.
- Talent Development: Experience up‑skilling junior HE staff.
- Broader Experience: Other experience beyond Health Economics (e. g., NHS).
- Therapy Area Experience: Experience in Cardiovascular, Renal & Metabolic therapy areas.
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life‑changing medicines.
In‑person working gives us the platform we need to connect, work at pace and challenge perceptions.
That’s why we work, on average, a minimum of three days per week from the office.
But that doesn’t mean we’re not flexible.
We balance the expectation of being in the office while respecting individual flexibility.
Join us in our unique and ambitious world.
Why Astra Zeneca?
At Astra Zeneca we’re dedicated to being a phenomenal Place to Work.
Where you are empowered to push the boundaries of science and fuel your ambitious spirit.
There’s no better place to make a difference to medicine, patients and society.
A broad culture that fosters diversity and teamwork, and always committed to lifelong learning, growth and development.
We’re on an exciting journey to pioneer the future of healthcare.
- Date Posted 09-Nov-2026
- Closing Date 16-Nov-2026
Our mission is to build an inclusive and equitable environment.
We want people to feel they belong at Astra Zeneca and Alexion, starting with our recruitment process.
We welcome and consider applications from all qualified candidates, regardless of characteristics.
We offer reasonable adjustments/accommodations to help all candidates to perform at their best.
If you have a need for any adjustments/accommodations, please complete the section in the application form.
Health Economics Manager, CVRM (9-months Secondment/FTC) in London employer: AstraZeneca Plc
AstraZeneca is an exceptional employer that fosters a culture of collaboration and innovation, making it an ideal place for a Study Monitor Support Specialist. With a commitment to employee growth through lifelong learning opportunities and a flexible work environment, you will be empowered to contribute to groundbreaking medical advancements while enjoying a supportive team atmosphere. Located in a vibrant area, AstraZeneca offers the chance to work alongside passionate professionals dedicated to making a meaningful impact in healthcare.
StudySmarter Expert Advice🤫
We think this is how you could land Health Economics Manager, CVRM (9-months Secondment/FTC) in London
✨Network with Local Healthcare Professionals
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✨Showcase Your Adaptability in Interviews
Temporary roles often require you to hit the ground running. Use your interviews to highlight any past experiences where you’ve had to adapt quickly, whether it’s in a volunteer position or a past job. This will show AstraZeneca Plc you’re ready to step in and make an immediate impact!
We think you need these skills to ace Health Economics Manager, CVRM (9-months Secondment/FTC) in London
Some tips for your application 🫡
Highlight Your Health Sciences Knowledge:When applying for the Health Economics Manager, CVRM (9-months Secondment/FTC) at AstraZeneca Plc, make sure to showcase any relevant courses or degrees you have in health sciences or related fields. This background helps to demonstrate that you understand the sector and can hit the ground running in a temporary role.
Emphasise Administrative Skills:Since this is an administrative role, it’s essential to highlight your organisational skills, attention to detail, and proficiency with software commonly used in health sciences administration. Mention any specific tools or systems you’ve used, as these can really make you stand out to AstraZeneca Plc.
Keep It Concise and Relevant:As this is a temporary role, brevity is key. Make sure your CV is succinct and focuses on your most relevant experiences. Highlight your ability to adapt quickly and learn on the job, which is crucial in a short-term position like this.
Tailor Your Cover Letter:Use your cover letter to express your enthusiasm for the health sciences sector and your interest in the specific tasks you'd be handling at AstraZeneca Plc. Being clear about why you're the perfect fit for a temporary position will help demonstrate your motivation and readiness to contribute.
How to prepare for a job interview at AstraZeneca Plc
✨Brush Up on Health Regulations
Given that you're diving into health sciences administration, make sure you're well-versed in the latest health regulations and compliance standards. It’s a temporary role, so showing that you’re up to speed with current guidelines will highlight your readiness to hit the ground running for AstraZeneca Plc.
✨Demonstrate Your Organisational Skills
In health sciences administration, organisational skills are key. Prepare examples of how you’ve managed multiple tasks or handled administrative challenges in the past. Be ready to speak about your tools—whether that's a particular software or a method of project management—that you use to keep everything in check.
✨Tailor Your Motivation to the Temporary Nature
As this is a temporary position, it’s essential to express your enthusiasm for the role during the interview. Talk about what you aim to learn and how you see this experience fitting into your overall career goals. Employers love to see that you’re eager to contribute, even if it's just for a short time!
✨Prepare for Scenario-Based Questions
You might also encounter scenario-based questions during your interview. Be ready to demonstrate how you'd handle specific administrative challenges in a health setting. Think about common situations in health sciences and formulate your responses beforehand, so you come off as calm and capable when it counts.
