Global Translational Medicine lead - Oncology

At Astellas, we are making treatments that matter to people. We are tackling the toughest health challenges putting the patient at the heart of every move we make. Our global vision for Patient Centricity is to support the development of innovative health solutions through a deep understanding of the patient experience. At Astellas, Patient Centricity isn’t a buzzword - it’s a guiding principle for action. We believe all staff have a role to play in creating a patient-centric culture and integrating an awareness of the patient into our everyday working practices, regardless of our role, team or division.

We have developed ground-breaking, innovative medicines in immunology, oncology and urology. Our medicines are extending and saving the lives of cancer patients, making transplantation possible and improving the quality of life for those living with conditions where needs are often overlooked. We take a patient-focused approach, that allows us to convert brilliant early science into treatments and solutions that directly improve and save patients’ lives. From lab to clinic to patient, we focus on the most promising science, empower the best talent to pursue it, and develop life-changing solutions alongside the best partners.

As Global Translational Medicine Lead Oncology, you will play a vital role in advancing healthcare through innovative solutions. By driving therapies that address unmet medical needs, you will help transform patient care worldwide. Your work will not only change lives today but also shape the future of medicine.

At Astellas, we recognise that our employees enjoy having a balance between their professional and home lives. We are proud of our hybrid approach which empowers you to have flexibility on whether to work from home or in the office. You will be part of an inclusive team that works to develop innovative therapies for patients.

• Develop and execute translational science and biomarker development plans in clinic.
• Drive understanding of mechanism of action and patient selection strategies.
• Contribute to overall clinical development strategy and trial design.
• Collaborate with clinical teams to implement biomarker sample collection in clinical studies.
• Drive analysis and interpretation of clinical biomarker data.
• Collaborate cross-functionally to translate preclinical science and deliver clinical biomarker data to impact clinical development.

• Extensive experience in drug discovery and development.
• Strong scientific background in cancer biology and oncology drug development.
• Experience in delivering pharmacodynamic, proof of mechanism, predictive biomarkers and understanding mechanism of action and resistance in clinic.
• Proven record of leading projects and delivering biomarker data in a matrix environment.
• Excellent collaboration, communication and interpersonal skills.
• Ability to think strategically and drive innovation.

• Experience in tumour driver/oncogene biology, with expertise in solid tumours such as lung, colorectal, prostate, and pancreatic cancer.
• Experience with ctDNA analysis.
• Experience in managing CROs.

• Advanced science degree (PhD, PharmD, or MD) or equivalent.

This position follows our hybrid working model. The role requires a blend of home and minimum 1 day per quarter in our local office. Flexibility may be required in line with business needs. Candidates must be located within a commutable distance of the office.

• A challenging and diversified job in an international setting.
• Opportunity and support for continuous development.
• Inspiring work climate.

We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.

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