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- Tasks: Develop and implement computational methods for analysing biological data in gene therapy.
- Company: Join AskBio, a pioneering gene therapy company transforming lives through innovative science.
- Benefits: Enjoy a collaborative work environment with opportunities for mentorship and professional growth.
- Why this job: Be part of groundbreaking research that aims to cure genetic diseases and make a real impact.
- Qualifications: PhD or Master's in bioinformatics with relevant experience; strong programming skills in Python required.
- Other info: This is an on-site position based in Edinburgh, UK, fostering a culture of collaboration.
The predicted salary is between 36000 - 60000 £ per year.
Scientist II, Bioinformatics page is loaded
Scientist II, Bioinformatics
Apply locations Edinburgh, UK time type Full time posted on Posted 4 Days Ago job requisition id R25-46
Asklepios BioPharmaceutical, Inc. (AskBio) is a leading, clinical-stage gene therapy company founded in 2001 based on the work of adeno-associated virus (AAV) gene therapy visionary and pioneer, Jude Samulski, PhD. Since that time, our commitment to developing life-saving medicines that can potentially cure genetic diseases has never wavered.
At AskBio, we’ve built a foundation of therapeutic programs, AAV manufacturing and a rich portfolio of patented technology. Our therapeutic focus includes neuromuscular, central nervous system, cardiovascular and metabolic diseases with clinical trials underway for Pompe disease, Parkinson’s disease, and congestive heart failure. Our gene therapy platform includes Pro10, an industry-leading proprietary cell line manufacturing process, and an extensive AAV capsid and promoter library.
We became a wholly-owned, independently operated, subsidiary of Bayer AG in late 2020 as a cornerstone of its newly formed Cell & Gene Therapy (CGT) platform. Our global headquarters is in Research Triangle Park, NC. Additionally, we have significant operations in Philadelphia, PA, Columbus, OH, Scotland, France, Germany, and Spain.
Our vision: Pioneering science to create transformative molecular medicines.
Our mission: Lead innovative science and drive clinical outcomes to transform people\’s lives.
Our principles:
- Advance innovative science by pushing boundaries.
- Bring transformative therapeutics to patients in need.
- Provide an environment for employees to reach their fullest potential.
Our values:
- Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.
- Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view.
- Embrace Responsibility. We are humbled by the enormity of our mission. We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers.
- Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.
- Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what’s right in every situation. Make clear commitments and follow through.
Position Summary
The Scientist II, Bioinformatics develops and implements computational methods for analysing proprietary biological data, supporting cross-functional teams with tailored bioinformatics solutions. Will have expertise in omics data analysis, statistical methods, and scientific programming. The role contributes to innovative computational research in gene therapy, advancing AskBio\’s platform-enabled product approach. This is a on-site based position in UK Edinburgh reporting to the Sr. Director, Bioinformatics and Machine Learning.
Job Responsibilities
- Develop and implement computational methods and algorithms for the analysis of proprietary biological data.
- Collaborate with cross-functional international teams to understand data analysis needs and provide tailored bioinformatics solutions.
- Contribute to the design and optimisation of bioinformatics pipelines and workflows to improve data processing and analysis.
- Stay up to date with advancements in bioinformatics, machine learning, and data science, integrating relevant approaches into ongoing work.
- Communicate findings and recommendations effectively to stakeholders, including senior leadership and non-expert audiences.
- Provide mentorship and guidance to junior team members, fostering a culture of collaboration and learning.
Minimum Requirements
- PhD in bioinformatics, computational biology, or a related discipline with at least 2+ years of postdoctoral or relevant industry experience; or Master’s degree in bioinformatics, computational biology, or a related field with at least 8 years of relevant industry or research experience.
- Strong programming skills in Python.
- Experience in statistical analysis of DNA sequence and molecular datasets.
- Proven ability to communicate complex computational analyses to both technical and non-technical audience.
- Expertise in processing and analyzing omic datasets, particularly next-generation sequencing (NGS) data.
- Familiarity with Unix/Linux-based systems and command-line environments.
Preferred Skills & Abilities
- Experience developing computational methods for biological data analysis.
- Experience working with clinical or translational research data.
- Proficiency in additional data analysis languages (e.g., R, MATLAB).
- Knowledge of containerization tools such as Docker.
- Familiarity with integrating multi-omics datasets.
- Experience with workflow management systems such as Snakemake or Nextflow.
- Knowledge of gene therapy and its bioinformatics challenges.
- Expertise in structural biology, particularly in protein structure modelling, interactions, and computational structural analysis.
- Experience contributing to cross-disciplinary and global research projects.
- Familiarity with version control systems (e.g., Git) and collaborative development practices.
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Scientist II, Bioinformatics employer: AskBio Inc.
Contact Detail:
AskBio Inc. Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Scientist II, Bioinformatics
✨Tip Number 1
Network with professionals in the bioinformatics field, especially those who have experience in gene therapy. Attend relevant conferences or webinars to meet potential colleagues and learn about the latest advancements in the industry.
✨Tip Number 2
Familiarise yourself with the specific tools and technologies mentioned in the job description, such as Docker and Snakemake. Having hands-on experience with these can set you apart during interviews.
✨Tip Number 3
Prepare to discuss your previous projects that involved omics data analysis and how you communicated complex findings to non-technical audiences. This will demonstrate your ability to fulfil a key requirement of the role.
✨Tip Number 4
Showcase your collaborative skills by highlighting any experience you have working in cross-functional teams. Be ready to provide examples of how you contributed to team success in past roles.
We think you need these skills to ace Scientist II, Bioinformatics
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in bioinformatics, computational biology, and any specific programming skills mentioned in the job description, such as Python. Use keywords from the job listing to demonstrate your fit for the role.
Craft a Compelling Cover Letter: Write a cover letter that not only outlines your qualifications but also reflects your passion for gene therapy and innovative science. Mention specific projects or experiences that align with AskBio's mission and values.
Showcase Your Technical Skills: In your application, emphasise your expertise in omics data analysis and statistical methods. Provide examples of how you've successfully applied these skills in previous roles or research projects.
Prepare for Communication: Since the role requires communicating complex analyses to diverse audiences, consider including examples of how you've effectively communicated technical information in the past. This could be through presentations, reports, or mentoring experiences.
How to prepare for a job interview at AskBio Inc.
✨Showcase Your Technical Skills
Be prepared to discuss your programming skills, especially in Python, and any experience you have with statistical analysis of DNA sequences. Highlight specific projects where you've developed computational methods for biological data analysis.
✨Demonstrate Collaboration Experience
Since the role involves working with cross-functional teams, share examples of how you've successfully collaborated with others in previous roles. Emphasise your ability to communicate complex analyses to both technical and non-technical audiences.
✨Stay Updated on Bioinformatics Trends
Research recent advancements in bioinformatics, machine learning, and data science. Be ready to discuss how you can integrate these trends into your work at AskBio, showing your commitment to continuous learning and innovation.
✨Prepare for Problem-Solving Questions
Expect questions that assess your problem-solving abilities, particularly in designing and optimising bioinformatics pipelines. Think of specific challenges you've faced and how you overcame them, as this will demonstrate your critical thinking skills.
