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- Tasks: Lead large-scale simulations to revolutionise drug discovery and mentor junior scientists.
- Company: AQEMIA, a pioneering drug invention company at the forefront of innovation.
- Benefits: Flexible work arrangements, competitive salary, and the chance to make a real impact.
- Why this job: Join a mission-driven team and shape the future of medicine with cutting-edge technology.
- Qualifications: MSc or PhD in relevant fields and 5+ years in molecular simulations.
- Other info: Collaborate with top talent in a dynamic environment focused on groundbreaking science.
The predicted salary is between 48000 - 72000 £ per year.
About AQEMIA
AQEMIA is a drug invention company dedicated to creating entirely new medicines to address major unmet medical needs. At the core of our mission is QEMI, our proprietary molecule-invention platform, which uniquely combines cutting-edge science with advanced technology. Powered by physics-based modeling, statistical mechanics, and generative AI, QEMI allows our teams to design novel drug candidates from first principles.
What makes AQEMIA different is our commitment to true innovation: our research is dedicated to the invention of new molecular entities, not the refinement of existing ones. We focus on inventing never-before-seen molecules, without relying on experimental data, and advancing them into a growing pipeline of proprietary programs and strategic partnerships with leading pharmaceutical companies. Our most advanced preclinical programs are currently in vivo optimization, targeting diseases still waiting for effective treatments, offering our teams the opportunity to work on science that can make a real difference in people’s lives.
About our Team
AQEMIA brings together a diverse, multidisciplinary team of 65+ professionals based in Paris and London. Our scientists and engineers, including chemists, physicists, machine learning experts, and software engineers, work side by side to push the boundaries of early-stage drug discovery. This close collaboration across disciplines is central to our approach, enabling us to tackle complex scientific challenges from first principles and translate cutting-edge ideas into novel therapeutic candidates. At AQEMIA, team members are encouraged to contribute their expertise, learn from one another, and play an active role in shaping the future of drug invention.
About the Team
The mission of the Molecular Simulations Team is threefold:
- Support drug discovery programs by maximizing the impact of binding free energy calculations in decision-making.
- Build, benchmark and continuously improve reproducible and scalable pipelines for binding free energy calculations, enabling support for multiple programs in parallel.
- Collaborate closely with our Physics Research Team to integrate innovations from Aqemia’s proprietary binding free energy methods.
Role Overview
As a Senior Application Scientist in the Molecular Simulations Team, you will be a scientific leader and technical expert, contributing to the strategy and delivery of Aqemia's Binding Free Energy Technology. You will help define and evolve how physics-based simulations inform and accelerate drug discovery decisions at Aqemia.
Key Responsibilities
- Design and lead large-scale simulation studies (e.g., relative and absolute binding free energy predictions).
- Evaluate and improve modeling protocols for reproducibility, accuracy, and efficiency.
- Serve as a mentor to junior scientists, promoting best practices in simulation and analysis.
- Contribute to cross-functional planning and the integration of simulations with experimental and AI-based insights.
- Stay at the forefront of developments in molecular simulations and suggest innovations to the team.
- Support the development and scaling of workflows that can serve multiple drug discovery projects.
- Work closely with the Research Team to implement improvements and updates to Aqemia’s proprietary binding free energy methods.
Qualifications & Experience
- MSc or PhD in Computational Chemistry, Biophysics, Statistical Mechanics, or related discipline.
- 5+ years of experience in molecular simulations, ideally within a drug discovery context.
- Deep knowledge of free energy methods, molecular dynamics, and simulation software.
- Strong programming/scripting ability and experience with workflow automation.
- Demonstrated ability to lead scientific projects and communicate effectively across disciplines.
Nice-to-Have
- Experience in machine learning applications for physics-based modeling.
- Track record of scientific publications and contributions to the computational drug discovery community.
Preferred Mindset
- Scientific Rigour: Champion high scientific standards and promote best practices across the team.
- Humble and Willing to Learn: Lead by example with curiosity and openness to new ideas.
- Excited by Challenging Scientific Problems: Passionate about solving complex, cutting-edge problems and guiding others through them.
- Pragmatic and Impact-Driven: Combine strategic thinking with practical execution to deliver real-world impact in a fast-paced environment.
- Leadership through Influence: Inspire and mentor colleagues while fostering a collaborative, high-performance culture.
Why Join Us?
At AQEMIA, we work for a mission: joining us means having your own impact on changing the way drugs are discovered, and helping to shape the direction of our fast-growing company and team.
Expanding Drug Discovery Pipeline
Focused on critical therapeutic areas like Oncology, CNS, Immuno-inflammation… with in vivo proof of concept/patent stage programs. Collaborations with top Pharma, including a $140M Sanofi deal.
World-Class Interdisciplinary Team
Work alongside exceptional talent at the intersection of technology and life sciences. Our teams combine deep expertise in AI, physics-based modeling, biology, and medicinal chemistry to push the boundaries of innovation.
DeepTech Recognition
AQEMIA is proud to be part of the French Tech 120 and France 2030, highlighting our role as a key player in Europe’s DeepTech ecosystem.
Prime Location with Flexibility
Our offices are located in the heart of Paris and London (King’s Cross), with flexible work arrangements including up to two remote days per week.
Strong Financial Backing
$100M raised from leading European and International investors.
Senior Application Scientist in London employer: Aqemia
Contact Detail:
Aqemia Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Application Scientist in London
✨Tip Number 1
Network like a pro! Reach out to professionals in the drug discovery field on LinkedIn or at industry events. A friendly chat can open doors that a CV just can't.
✨Tip Number 2
Show off your skills! Prepare a portfolio or presentation that highlights your past projects and successes in molecular simulations. This is your chance to shine beyond the application.
✨Tip Number 3
Practice makes perfect! Get a friend or mentor to do mock interviews with you. This will help you articulate your experience and passion for drug invention clearly.
✨Tip Number 4
Apply through our website! It’s the best way to ensure your application gets noticed. Plus, it shows you're genuinely interested in being part of AQEMIA's innovative team.
We think you need these skills to ace Senior Application Scientist in London
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to the Senior Application Scientist role. Highlight your experience in molecular simulations and any relevant projects that showcase your skills in drug discovery. We want to see how you can contribute to our mission!
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you're passionate about drug invention and how your background aligns with AQEMIA's innovative approach. Let us know what excites you about the role and our team.
Showcase Your Technical Skills: Don’t forget to highlight your programming and scripting abilities, especially if you've automated workflows or improved simulation protocols. We love seeing candidates who can bring practical solutions to complex problems!
Apply Through Our Website: We encourage you to apply directly through our website. It’s the best way for us to receive your application and ensures you’re considered for the role. Plus, it shows you’re keen on joining our team at AQEMIA!
How to prepare for a job interview at Aqemia
✨Know Your Science
Make sure you brush up on your knowledge of molecular simulations and binding free energy methods. Be prepared to discuss specific techniques you've used in past projects, as well as any innovations you might suggest for AQEMIA's approach.
✨Showcase Your Leadership Skills
As a Senior Application Scientist, you'll be expected to mentor junior scientists. Think of examples where you've led projects or teams, and be ready to share how you foster collaboration and best practices in a scientific setting.
✨Prepare for Cross-Disciplinary Questions
Since AQEMIA values collaboration across different fields, expect questions that assess your ability to communicate and work with chemists, physicists, and AI experts. Have examples ready that demonstrate your experience in cross-functional teamwork.
✨Stay Current with Industry Trends
Keep yourself updated on the latest developments in drug discovery and molecular simulations. Being able to discuss recent advancements or challenges in the field will show your passion and commitment to innovation, which is key for AQEMIA.
