Biostatistics Senior Manager - HTA

Join us to apply for the Biostatistics Senior Manager - HTA role at Amgen. If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission—to serve patients—drives all that we do. We are global collaborators who achieve together—researching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of.

In this role, you will play a pivotal role in the development of centralised biostatistical capabilities in the Center for Design and Analysis (CfDA) to meet Health Technology Assessment (HTA) requirements, including design and analysis tools, templates, code library, and reference materials. As an experienced biostatistician, you will establish analysis and reporting processes and good practice related to HTA, collaborating with cross-functional stakeholders. You will provide statistical input and subject matter expertise on innovative and fit-for-purpose clinical trial design and data analysis to meet HTA needs.

Key Responsibilities

• Advocate for increased knowledge within CfDA on new EU HTA regulation, its impact, and implementation phases.
• Ensure effective collaboration between CfDA and HEOR throughout the product lifecycle and implement strategies to increase HTA knowledge and expertise within CfDA.
• Provide consulting and hands-on support for CfDA team members undertaking analyses for HTA purposes.
• Provide statistical expertise in causal inference, indirect comparison, PRO evaluation, and subgroup analysis.
• Development and maintenance of resources for HTA purposes, including TFL shell and code library.
• Interact with multifunctional internal stakeholders and Subject Matter Experts to develop data-driven solutions for HTA business needs.
• Network with HTA Subject Matter Experts across industry.
• Involvement in process development and maintenance of statistical activities related to HTA.

You would be joining a global team of statisticians, data scientists, and statistical programmers in the CfDA function. The role is within the Design & Innovation subfunction, engaging with team members working on innovative solutions to support product development.

What We Expect Of You

• Degree in Statistics/Biostatistics or related field with high statistical content and postgraduate experience in biopharmaceutical industry or medical research.
• Superior understanding of statistical principles, especially related to HTA.
• Proficiency in R and SAS software.
• Experience in life cycle drug development.
• Excellent analytical and problem-solving skills.
• Experience working in a global team and with cross-functional partners.
• Strong communication skills, both oral and written.
• Experience in policy and SOP development.

What You Can Expect Of Us

• A strategic vision leveraging quality, operational excellence, and talent.
• Diverse, inclusive community where ideas are valued.
• Generous Total Rewards including health, finance, work/life balance, and career benefits.

Location: Flexible work from home with regular office work in Cambridge or Uxbridge, UK. Fully remote considered.

Join us in a career that defies imagination.

Amgen is an Equal Opportunity employer. We consider all applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran status, or disability. Reasonable accommodations are available upon request.