At a Glance
- Tasks: Lead innovative clinical research in developing RNAi therapeutics for liver diseases.
- Company: Join Alnylam Pharmaceuticals, a pioneering biotech firm focused on transformative therapies.
- Benefits: Hybrid work model, competitive salary, and opportunities for professional growth.
- Other info: Collaborative environment with a focus on innovation and scientific excellence.
- Why this job: Make a real impact in drug development and shape the future of medicine.
- Qualifications: MD or MD/PhD with extensive experience in clinical research and drug development.
The predicted salary is between 100000 - 150000 £ per year.
Alnylam Pharmaceuticals is seeking an imaginative physician drug developer. This is an opportunity to provide clinical leadership in developing RNAi therapeutics in Alnylam’s rapidly expanding portfolio, which spans the areas of rare genetic diseases, cardio-metabolic diseases, neuroscience, hematology and hepatology.
The successful candidate’s primary role will be to drive the pipeline forward through leadership of clinical development programs. While the primary focus responsibility will be as clinical lead physician on Alnylam’s autoimmune liver disease programs, the role may support across a range of therapeutic areas and all stages of development may be required as pipeline assets evolve. He/she is expected to play a leading and influencing role in the overall clinical development strategies and drive progress and operational excellence for associated clinical trials.
In addition, this role will include interaction with Alnylam’s research group, helping to advise the team on the clinical development feasibility of novel targets and the design of proof-of-concept studies. This work will also involve extensive consultation and collaboration with external experts. It is expected that additional opportunities will arise to lead bench-to-bedside early phase clinical development programs.
The Senior Director, Clinical Research, will work in a matrix organization across Regulatory, Biostatistics, Clinical Operations, Preclinical, Commercial & QA teams to ensure fully harmonized and integrated development strategies. He/she will be a key Alnylam Development spokesperson at external meetings, including regulatory interactions and scientific meetings.
This position is hybrid and will be primarily located at our Cambridge, MA headquarters or Maidenhead, UK location.
Key Responsibilities- Be the strategic leader providing a strong, clear voice for the clinical programs
- Develop creative but realistic approaches to drug development and lead clinical efforts to secure global regulatory approvals
- Oversight of trial conduct and safety
- Provide strategic consultation and guidance to Research on all decisions that have significant clinical components and implications.
- Collaborate closely with Preclinical, Regulatory Affairs, Medical Affairs and Commercial to ensure tight strategic integration of product development plans
- Be accountable via Clinical Research and Operations for all relevant timelines and deliverables
- Drive/supervise all major written deliverables (regulatory submissions, original articles, abstracts), and presentation materials
- Be responsible (as appropriate in line with SOPs) for final review and sign off with respect to all controlled documents including protocols, IBs, informed consent forms
- Influence internal and external audiences in a high impact, highly visible fashion
- MD with strong research background or MD PhD, with a track record of successful research support and peer review publications. Board Certification (or equivalent) or specialist training is highly desirable; drug development experience in hepatology (autoimmune liver disease) would be a great advantage, but not essential
- 10+ years industry experience or equivalent clinical academic experience
- Sound scientific and clinical judgment
- Successful track record of leading Phase 2/3 clinical programs, including major interactions with Health Authorities
- Familiarity with concepts of clinical research and clinical trial design, including biostatistics, regulatory agency organization, guidelines, and practices
- Ability to effectively present ideas and document complex medical/clinical concepts in both written and oral communication
- History of solving problems while exhibiting superior judgment and a balanced, realistic understanding of issues
- Outstanding leadership and collaboration skills working within a matrix environment.
- Experience and knowledge of working with biotech/pharma partner(s) a plus
- Thrives in highly entrepreneurial biotech environment and embraces Alnylam’s culture of science, passion and urgency.
Senior Medical Director, Clinical Research- Hepatology in Maidenhead employer: Alnylam Pharmaceuticals
Alnylam Pharmaceuticals is an exceptional employer, offering a dynamic and innovative work environment in the heart of Cambridge, MA or Maidenhead, UK. With a strong focus on employee growth and collaboration, we provide opportunities for our team to lead groundbreaking clinical research in RNAi therapeutics while enjoying a hybrid work model that promotes work-life balance. Our culture fosters creativity and excellence, making it an ideal place for passionate professionals looking to make a meaningful impact in the field of medicine.
StudySmarter Expert Advice🤫
We think this is how you could land Senior Medical Director, Clinical Research- Hepatology in Maidenhead
✨Join Medical Networks
Get involved in local and national medical associations, like the Royal College of Physicians. These networks can help you connect with mentors and colleagues who might know of openings, plus they're great for staying updated on the latest in medicine and clinical practices.
✨Attend Healthcare Conferences
Make it a habit to attend medical conferences and seminars. These events are fantastic for networking and often feature job boards where hospitals and clinics post their openings. Plus, it’s a good way to get your face recognised in the industry.
✨Leverage Your Medical School's Resources
Don’t forget to use your medical school’s career services! They usually have great connections with hospitals and clinics looking to fill full-time physician positions and can help you with mock interviews or networking events.
✨Apply Directly Through Hospital Websites
When you're ready to apply, make sure to check the careers section of hospital websites directly. Hospitals like Alnylam Pharmaceuticals often post their job openings there first, and applying directly can sometimes give you an edge over other applicants.
We think you need these skills to ace Senior Medical Director, Clinical Research- Hepatology in Maidenhead
Some tips for your application 🫡
Show Off Your Credentials:When applying for a physician role, make sure to highlight your medical qualifications and any special certifications you have. We want to see your medical degree, residency training, and any additional certifications that set you apart, like specialised training in paediatrics or geriatrics. Don’t leave out those all-important letters after your name!
Tailor Your CV to Medicine:Your CV should reflect your experience and skills as a doctor. Be specific about your clinical rotations, medical practice, and any research work you've done – we love seeing quantifiable impacts, so mention how you've improved patient care or led successful treatment plans.
Craft a Personal Statement with Heart:In your cover letter, let us know why you chose medicine and what drives your passion for patient care. Personal stories about transformative experiences—like a memorable patient encounter or a moment that defined your career path—can really make you shine. Remember, we're looking for someone who genuinely cares about their patients!
Demonstrate Continuous Learning:In the medical field, showcasing your commitment to continuous learning is essential. Mention any recent courses, workshops, or conferences you’ve attended, and highlight your willingness to stay updated on medical advancements. This shows us that you’re not just a physician; you're a lifelong learner, ready to adapt and grow.
How to prepare for a job interview at Alnylam Pharmaceuticals
✨Get Clinical Knowledge Sharp
Brush up on your clinical knowledge, particularly in areas relevant to the role at Alnylam Pharmaceuticals. Expect questions about diagnosis, treatment plans, and patient management. Be ready to discuss case studies or even do some role-playing with hypothetical patient scenarios for a more practical assessment.
✨Know Your Procedures and Protocols
Familiarise yourself with the latest procedures and protocols that are specific to the field of medicine you’re applying to. Whether it’s surgical techniques or patient care protocols, being able to discuss these confidently can really set you apart in the interview at Alnylam Pharmaceuticals.
✨Show You're a Team Player
In the medical field, collaboration is key. Have examples ready that showcase your teamwork and communication skills. Talk about how you've worked with nurses, specialists, or other doctors in the past to provide the best care for your patients. This shows you're ready to integrate into the team at Alnylam Pharmaceuticals.
✨Stay Current with Medical Trends
Make sure you’re clued up on the latest medical trends, research, and innovations. Not only does this prepare you for technical questions, but it also shows your passion for the field. Be ready to discuss how these trends might affect your practice at Alnylam Pharmaceuticals.
