Medical Affairs Manager in Maidenhead

This role is considered [[custWorkplaceType]]. The role requires development of a deep understanding of the relevant therapy area, as well as the clinical development and data supporting Alnylam medicines within the scope of the Medical Affairs Manager role. As a true subject matter expert, the Medical Affairs Manager has a high degree of credibility both internally and externally. They are expected to develop a strategic KOL network and to use engagements with these individuals to systematically gather relevant insights for Alnylam and, where appropriate, to challenge and influence the thinking of leading clinicians.

The Medical Affairs Manager provides compliance support in respect of activities and materials generated across the cross‑functional Brand Team and will be expected to undergo ongoing training and validation in their ABPI final signatory role. They will also play a key role in assimilating and sharing insights gathered from HCPs to influence cross‑functional brand strategy and develop the medical tactical plan. They will be responsible for developing and delivering a range of medical activities, including insight gathering (incl advisory boards), medical education, scientific communication and real‑world evidence generation. The Medical Affairs Manager may be required to support Patient Advocacy and Engagement (PAE) to enhance Alnylam’s patient‑focused culture, collaborating with the PAE team to enable communications, gain insight and identify collaboration opportunities with patient advocacy groups and patients.

This role has a predominant focus on field‑based activities, with responsibility for all key external stakeholders in the Medical Affairs team at National level in the designated Therapeutic Areas (TAs). The successful candidate will be required to travel, including spending a minimum of a day per week in the Maidenhead office and possibly overnight stays to balance field and office based activities.

• Develop and continuously maintain the highest scientific and medical expertise within the designated therapeutic area and be acknowledged internally and externally as an expert in this area, developing peer‑to‑peer scientific relationships with HCPs and giving medical support to the corresponding cross‑functional disease area teams.
• Identify key opinion leaders and cultivate a network of experts for the designated therapeutic area, acting as an Alnylam ambassador.
• Maintain ongoing knowledge base on the ABPI Code of Practice and understanding of the compliance environment, identifying and implementing optimisation of Alnylam processes where appropriate.
• Initiate and support high‑impact medical education activities, including congress symposia, hospital meetings and speaker development programmes; provide medical and scientific input into the planning and execution of advisory boards.
• Actively engage with the Country Brand Team to provide medical leadership within the designated therapeutic area to ensure the effective local implementation of Alnylam strategy and appropriate use of local market intelligence and development opportunities.
• Actively engage with International & Global Medical Affairs and other functions, providing medical leadership within the designated therapeutic area.
• Collaborate with health care professionals to identify opportunities for the development of algorithms and guidelines to facilitate early diagnosis.
• Support the efforts of patient support groups.
• Where appropriate and strategically aligned, lead the design, execution and oversight/governance of patient support programmes.
• Manage requests for Alnylam product supply in off‑label and compassionate use cases in accordance with local and Alnylam procedures.

• UK registered MD (Medical Doctor) and/or UK registered Pharmacist.
• Detailed understanding of the ABPI and IPHA Codes of Practice.
• Excellent fluent and verbal English, with ABPI and IPHA final signatory status.
• Prior experience in rare and specialty disease areas.
• Proven basic science and/or clinical background to enable engagement of health care professionals in a scientifically meaningful exchange.
• Good analytical skills as applied to medical, scientific and technical information.
• Experience in real‑world evidence generation.
• Experience in medical education and KOL management.
• Effective communication of evidence‑based scientific information.
• Knowledge of aspects of drug development, GCP and local regulations.
• Ability to work collaboratively and cross‑functionally.
• Management and planning skills as well as decision‑making and accountability.
• Confident and has the professional competence to win respect and gain credibility at all levels within and outside the company; capable of representing the company externally.

About Alnylam: Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize‑winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality.

Our Culture: Our people‑first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognised as one of Science Magazine’s Top Biopharma Employers, one of America’s Most Responsible Companies for 2024 by Newsweek, a Fast Company Best Workplace for Innovators and a Great Place to Work in Canada, France, Italy, Spain, Switzerland and the UK – among others. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.