At a Glance
- Tasks: Design and optimise crystallisation processes for pharmaceutical development.
- Company: Join Almac Sciences, a leader in custom synthesis for the pharmaceutical industry.
- Benefits: Enjoy professional development, staff discounts, and an attractive compensation package.
- Other info: Flexible working hours and excellent opportunities for long-term career progression.
- Why this job: Make a real impact on human health while advancing your career in a supportive environment.
- Qualifications: Degree in Chemistry or related field; experience in crystallisation process development required.
The predicted salary is between 40000 - 50000 £ per year.
Location: Craigavon, Northern Ireland
Hours: 37.5 Hours per week, Monday to Friday. Flexible working hours.
The Business Unit Almac Sciences provides a wide range of custom synthesis services, technology, and products to the pharmaceutical industry, supporting our clients from drug discovery to commercialisation of new chemical entities. We can offer a complete set of solutions aimed at accelerating entry into early-stage clinical development. Advancing human health requires exceptional people - your talent, experience and passion will be the perfect match. Together we will make an exceptional difference to the health of countless patients all over the world. Joining Almac means becoming part of a fast-paced, growing organisation within a highly regulated industry. We offer a supportive and collaborative working environment, with excellent opportunities for learning, development and long-term career progression across the Almac Group. Our approach is simple: we support, develop and reward our people, build fulfilling careers and together we advance human health.
The Opportunity The Crystallisation Process Scientist will be responsible for the design, development, and optimisation of crystallisation processes for API and key intermediate isolation and purification. The role involves applying fundamental understanding of solid-state chemistry, phase behaviour, and particle engineering to deliver robust, scalable crystallisation processes suitable for transfer to kilo lab, pilot and GMP manufacturing plants. Depending on your experience, you will provide technical leadership across projects, identifying and mitigating risks associated with crystallisation, solid form control, and downstream processing, while ensuring delivery to client timelines and regulatory expectations.
- Design and execute crystallisation process development studies, including solvent selection, supersaturation control, and seeding strategies
- Develop robust crystallisation procedures for solid form control (polymorph, solvate, hydrate selection)
- Apply thermodynamic and kinetic principles to optimise nucleation, crystal growth, and particle size distribution
- Conduct solid-state and particle characterisation using appropriate analytical techniques (e.g., XRPD, DSC, microscopy)
- Define and control critical process parameters (CPPs) and critical material attributes (CMAs) related to crystallisation
- Support scale-up and technology transfer to pilot plant or kilo lab, ensuring process robustness and reproducibility
- Troubleshoot crystallisation challenges including oiling out, agglomeration, poor filtration, and polymorphic instability
- Collaborate with synthetic chemistry, analytical, and engineering teams to ensure integrated process understanding
- Maintain clear and compliant documentation aligned with GMP and CMC expectations
- Provide technical input for client discussions, reports, and regulatory documentation
Essential Candidate Criteria:
- Degree (or equivalent) in Chemistry, Chemical Engineering, or closely related discipline
- Demonstrated experience in crystallisation process development and solid-state chemistry
- Strong understanding of phase diagrams, solubility, and crystallisation kinetics
- Experience with scale-up considerations and process robustness in an industrial setting
- Proven ability to solve complex crystallisation and isolation challenges
Desirable Criteria:
- Postgraduate qualification (MSc/PhD) in Crystallisation, Solid-State Chemistry, or Particle Engineering
- Experience with PAT tools (e.g., FBRM, PVM) and advanced crystallisation monitoring
- Knowledge of polymorph screening and crystallisation risk management strategies
- Familiarity with GMP environments and regulatory expectations (CMC)
As part of a busy team within a rapidly growing organisation, operating within a challenging industry you will benefit from the numerous personal and professional developmental opportunities available throughout the Almac group.
Closing Date: Sunday 14th June 2026 at 5pm
Skills: Chemistry, Knowledge of GMP, scale up, chemistry, crystallisation
Benefits: Professional Development + Growth, Staff Discounts, Attractive Compensation Package, Employee Recognition, Rewards for Years Of Service, Group Healthcare Scheme, Pension Scheme
Senior Crystallisation Process Development Chemist in Craigavon employer: Almac Group Ltd
Almac Sciences is an exceptional employer located in Craigavon, Northern Ireland, offering a dynamic and supportive work environment that prioritises employee growth and development. With flexible working hours and a commitment to advancing human health, Almac provides numerous opportunities for professional advancement, competitive compensation, and a comprehensive benefits package, making it an ideal place for talented individuals to thrive in the pharmaceutical industry.
StudySmarter Expert Advice🤫
We think this is how you could land Senior Crystallisation Process Development Chemist in Craigavon
✨Tip Number 1
Network like a pro! Reach out to professionals in the crystallisation and pharmaceutical fields on LinkedIn. Join relevant groups, attend webinars, and don’t be shy about asking for informational interviews. You never know who might have the inside scoop on job openings!
✨Tip Number 2
Prepare for those interviews by brushing up on your technical knowledge. Make sure you can discuss crystallisation processes, solid-state chemistry, and any relevant experience confidently. Practise common interview questions and think of examples that showcase your problem-solving skills.
✨Tip Number 3
Showcase your passion for advancing human health! When you get the chance to speak with potential employers, share why you’re excited about the role and how your background aligns with their mission. A genuine connection can set you apart from other candidates.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen by the right people. Plus, it shows you’re serious about joining Almac and contributing to our mission of making a difference in healthcare.
We think you need these skills to ace Senior Crystallisation Process Development Chemist in Craigavon
Some tips for your application 🫡
Tailor Your CV:Make sure your CV is tailored to the Senior Crystallisation Process Development Chemist role. Highlight your experience in crystallisation process development and solid-state chemistry, as these are key areas for us.
Showcase Relevant Skills:Don’t forget to showcase your understanding of phase diagrams, solubility, and crystallisation kinetics. We want to see how your skills align with what we’re looking for!
Be Clear and Concise:When writing your application, keep it clear and concise. Use bullet points where possible to make it easy for us to read through your qualifications and experiences.
Apply Through Our Website:We encourage you to apply through our website for a smoother application process. It’s the best way for us to receive your application and get you on board with Almac!
How to prepare for a job interview at Almac Group Ltd
✨Know Your Chemistry
Brush up on your solid-state chemistry and crystallisation processes. Be ready to discuss specific techniques you've used, like solvent selection or seeding strategies, and how they relate to the role. This shows you’re not just familiar with the theory but can apply it practically.
✨Showcase Problem-Solving Skills
Prepare examples of complex crystallisation challenges you've faced and how you resolved them. Whether it was dealing with polymorphic instability or poor filtration, having concrete examples will demonstrate your ability to think critically and adapt in a fast-paced environment.
✨Understand Regulatory Expectations
Familiarise yourself with GMP environments and CMC expectations. Be prepared to discuss how you’ve maintained compliance in past roles, as this is crucial for the position. Showing that you understand the importance of documentation and regulatory standards will set you apart.
✨Collaborate and Communicate
Highlight your experience working with cross-functional teams, such as synthetic chemistry and analytical teams. Discuss how effective communication has helped you deliver projects on time and meet client expectations. This role requires collaboration, so showing you can work well with others is key.