At a Glance
- Tasks: Conduct innovative research in oncology to develop life-changing medicines.
- Company: AstraZeneca, a leader in transforming cancer treatment through science.
- Benefits: Collaborative culture, professional growth, and impactful work in healthcare.
- Other info: Opportunity to work with cutting-edge technology and make a real difference.
- Why this job: Join a passionate team dedicated to eliminating cancer and improving patient lives.
- Qualifications: PhD or equivalent in immunology/cancer biology with strong lab skills.
The predicted salary is between 49500 - 60500 £ per year.
Location: Cambridge (Discovery Centre)
Introduction to the Role: At AstraZeneca, we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. We're passionate about the potential of science to address the unmet needs of patients around the world. We commit to those areas where we believe we can really change the course of medicine and bring big new ideas to life. Are you ready to work on one of the most exciting Oncology pipelines in industry?
About the Role: AstraZeneca's vision in Oncology is to push the boundaries of science to change the practice of medicine, transform the lives of patients living with cancer, and to ultimately eliminate cancer as a cause of death. We are seeking a highly motivated Senior Scientist with deep scientific and technical expertise spanning both adaptive and innate immune cell biology with a track record of scientific excellence to join Immune Cell Engagers Discovery team in Cambridge, UK for a 12-month period. As a Senior Scientist, you will be a key member of a team focused on supporting immune-oncology projects through the drug discovery process. You will bring your theoretical and practical expertise in immunology to establish assay systems and deliver datasets that will have direct impact on immune-oncology research projects.
Main Duties and Responsibilities: Working in this laboratory-based position within the Immune Cell Engagers Discovery group, you will develop, design, conduct and analyse in- ex- vivo experiments to assess the function of our candidate drugs and help us to dissect the mechanism of action of novel therapeutics targeting the immune system for cancer therapy. You will also review emerging literature and internal data to help in identifying new potential targets and contribute to target validation activities.
- A strong foundation in immunology / immuno-oncology, and an in-depth technical expertise for the analysis of immune function and phenotype is essential for this role.
- As a highly organised and self-motivated individual with a strong lab/practical background, you will stay up to date with relevant technical and intellectual scientific expertise in tumour immunology and have a genuine passion for this field of research!
- A PhD, or equivalent experience, in immunology/Immuno-oncology/ cancer biology.
- Extensive background in immunology and/or immuno-oncology.
- Experience of a range ex- vivo technical skills for the analysis of human immune cell functions via multiparameter flow cytometry, ELISA/multiplex assays, ELISPOT, primary immune cell isolation and co-cultures, cell killing assays (like TDCC, ADCC, CDC, ADCP), TILs isolation and phenotyping.
- Molecular biology skills including gene expression analysis and stable cell line generation.
- Working experience with immune cell assays and/or characterization is highly desirable.
- Strong interpersonal, influencing, negotiating and collaboration skills together with evidence of having used these skills to support problem solving and in delivering the projects in a collaborative environment.
- Depth of understanding and strong enthusiasm for immunology and immuno-oncology.
- Proven track record of scientific accomplishments, as evident from publications/patents.
- Data processing, statistical analysis, and interpretation.
- Experience in preparing written scientific reports (e.g., manuscripts) and oral presentations (e.g., slides, posters).
- Ability to record protocols and experiments in a timely manner and maintain an excellent electronic notebook (eLNB).
We encourage applications from candidates who have experience in the evaluation of immune cell functions and in developing and deploying complex immunological assays to understand the MOA of novel therapeutics. Expertise in fields of T-cell engagers, T cell exhaustion, tumour myeloid and/or NK biology. Experience in visualizing/quantifying high content multi-parameter flow cytometry data /transcriptomic datasets. Candidates who can demonstrate proficiency in leveraging AI technologies, including machine learning, data analysis, and algorithm development to enhance research outcomes, alongside strong problem solving skills, to enable integration of these tools into scientific workflows are strongly preferred. Prior experience with spectral flow cytometry. Working experience with 3D cell culture. Experience in working with patient-derived tumours/TILs. Knowledge of the drug discovery process.
Why AstraZeneca? Join a company where rigorous science meets real-world impact. You will operate with high visibility and growing responsibility, shaping deliverables that influence key decisions across global therapy areas. Expect a collaborative environment that brings diverse minds together, uses advanced tools and technology to solve tough problems, and recognizes both progress and learning. We balance bold ambition with support-valuing curiosity, resilience and kindness-so you can stretch your skills, contribute to breakthroughs and see the patient impact of your work.
Where can I find out more? Our Social Media, Follow AstraZeneca on LinkedIn, Follow AstraZeneca on Facebook, Follow AstraZeneca on Instagram.
Senior Scientist (12-Month Fixed Term Contract) in Cambridge employer: Allscreens Nationwide Ltd
Allscreens Nationwide Ltd is an exceptional employer, offering a supportive and inclusive work culture that prioritises the wellbeing of both employees and the individuals they serve. With a strong focus on professional development, team leaders are encouraged to grow their skills in a dynamic environment while making a meaningful impact in the lives of adults with learning disabilities. Located in Leicester, the company provides a unique opportunity to be part of a dedicated team committed to delivering high-quality, person-centred care.
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We think this is how you could land Senior Scientist (12-Month Fixed Term Contract) in Cambridge
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We think you need these skills to ace Senior Scientist (12-Month Fixed Term Contract) in Cambridge
Some tips for your application 🫡
Showcase Relevant Lab Skills:In the biotech world, your lab skills are paramount. Make sure your CV highlights specific techniques and equipment you’ve used, such as PCR, gel electrophoresis, or cell culture. This will give us a clear picture of what you can bring to Allscreens Nationwide Ltd as a temporary teammate.
Highlight Your Research Experience:If you’ve worked on any research projects — whether during your studies or in previous positions — make sure to detail these in your application. Include the objective, your role, and what you achieved. This will help us see your potential and fit for the temporary position at Allscreens Nationwide Ltd.
Keep It Concise and Relevant:Especially for a temporary role, we want to see a clear and focused application. Tailor your CV and cover letter to emphasise the qualifications and experiences that are most relevant to the biotech field and the specific role at Allscreens Nationwide Ltd. This shows us you’re genuinely interested and capable.
Be Clear About Your Availability:Since it’s a temporary role, let us know right away when you’re available to start and how long you can commit. Include this in your cover letter — this kind of transparency saves us all time and helps us find the right fit quickly at Allscreens Nationwide Ltd.
How to prepare for a job interview at Allscreens Nationwide Ltd
✨Brush Up on Your Biotech Basics
Understanding the fundamental concepts in biotechnology is crucial. Be ready to discuss core topics like genetics, molecular biology, or bioinformatics, especially if you're asked technical questions. We suggest revisiting your coursework or recent projects to refresh your memory.
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If you’ve got hands-on experience in lab settings, now’s the time to showcase it. Talk about specific techniques you’ve mastered, like PCR or chromatography, and any relevant safety protocols you’ve followed. These details help paint you as an effective team member from day one.
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Hiring managers want to see your motivation, especially for a temporary position in a fast-paced field like biotechnology. Be ready to discuss what excites you about the industry, your career goals, and how this role at Allscreens Nationwide Ltd aligns with them. It’s all about showing that you’re not just looking for a job, but a stepping stone in your biotech journey.
