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- Tasks: Manage clinical trials, ensuring compliance and supporting investigative sites across England.
- Company: Join a leading global CRO known for innovative solutions in clinical development.
- Benefits: Enjoy competitive salary, flexible working, and clear career progression opportunities.
- Why this job: Work on cutting-edge therapies like CAR-T and gene therapy in a supportive, collaborative culture.
- Qualifications: Bachelor’s degree in Life Sciences or related field; 3 years UK monitoring experience preferred.
- Other info: Full training provided; ideal for ambitious CRAs looking to advance their careers.
The predicted salary is between 36000 - 60000 £ per year.
Senior Clinical Research Associate – England
Chloe O’Shea is proud to partner with a leading global CRO renowned for delivering innovative, high-quality solutions in clinical development. We are seeking an experienced Senior Clinical Research Associate (Senior CRA) to join a dedicated single-sponsor team in England. This is an exciting opportunity to work on cutting-edge studies, with a particular focus on advanced therapy areas such as CAR-T and gene therapy. While prior experience in these fields is highly valued, it is not essential – full training and support will be provided.
The Role
As a Senior CRA, you will be a key contributor to the successful delivery of clinical trials across England. You will oversee site management activities, act as a primary liaison with investigative sites, and ensure strict compliance with protocols, ICH-GCP, and UK regulatory requirements (MHRA/REC). This role is well-suited to ambitious CRAs ready to step up or established Senior CRAs seeking to deepen their expertise in innovative therapy areas.
Key Responsibilities
- Independently manage qualification, initiation, monitoring, and close-out visits across England.
- Ensure high standards of compliance with ICH-GCP, MHRA, REC requirements, and sponsor SOPs.
- Perform source data verification, investigational product accountability, and ensure accurate site documentation.
- Serve as a trusted partner to site personnel, offering training, guidance, and ongoing support.
- Identify site-level challenges proactively and drive timely resolution.
- Contribute to mentorship of junior CRAs and share best practices within the monitoring team.
- Maintain complete and accurate trial documentation in CTMS, eTMF, and EDC systems.
Requirements
- Bachelor’s degree in Life Sciences, Nursing, Pharmacy, or a related discipline.
- Minimum 3 years of independent UK monitoring experience, ideally with exposure to complex studies.
- Experience in CAR-T and/or gene therapy is highly desirable but not required.
- Strong knowledge of ICH-GCP and UK clinical trial regulations (MHRA/REC).
- Excellent communication, relationship-building, and organisational skills.
What’s in It for You?
This role offers a competitive salary and benefits package , flexible working arrangements, and clear opportunities for career progression within one of the world’s largest CROs. You’ll gain exposure to innovative therapies shaping the future of healthcare, while working in a collaborative culture that values professional development, work-life balance, and wellbeing.
If you are a driven Senior CRA — or an experienced CRA ready to take the next step — we’d love to hear from you. Apply today to join a global team making a meaningful difference in patients’ lives.
Senior Clinical Research Associate employer: AL Solutions
Contact Detail:
AL Solutions Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Clinical Research Associate
✨Tip Number 1
Network with professionals in the clinical research field, especially those who have experience in CAR-T and gene therapy. Attend industry conferences or local meetups to connect with potential colleagues and learn more about the latest trends and challenges in these advanced therapy areas.
✨Tip Number 2
Familiarise yourself with ICH-GCP guidelines and UK regulatory requirements if you haven't already. Consider taking online courses or attending workshops that focus on these regulations to demonstrate your commitment to compliance and enhance your knowledge base.
✨Tip Number 3
Prepare for interviews by practising common questions related to site management and monitoring. Be ready to discuss specific examples from your past experiences where you successfully resolved site-level challenges or mentored junior CRAs.
✨Tip Number 4
Showcase your organisational skills by discussing how you manage trial documentation and ensure compliance during your previous roles. Highlight any tools or systems you've used, such as CTMS or EDC, to streamline processes and maintain accuracy.
We think you need these skills to ace Senior Clinical Research Associate
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in clinical research, particularly any roles that involved monitoring or managing clinical trials. Emphasise your knowledge of ICH-GCP and UK regulations, as well as any specific experience with advanced therapies like CAR-T or gene therapy.
Craft a Compelling Cover Letter: Write a cover letter that showcases your passion for clinical research and your desire to work in innovative therapy areas. Mention how your background aligns with the responsibilities of the Senior CRA role and express your enthusiasm for contributing to cutting-edge studies.
Highlight Key Skills: In your application, focus on key skills such as communication, relationship-building, and organisational abilities. Provide examples of how you've successfully managed site-level challenges or mentored junior CRAs in previous roles.
Proofread Your Application: Before submitting, carefully proofread your CV and cover letter for any spelling or grammatical errors. A polished application reflects your attention to detail, which is crucial in clinical research.
How to prepare for a job interview at AL Solutions
✨Know Your Regulations
Familiarise yourself with ICH-GCP and UK clinical trial regulations, including MHRA and REC requirements. Being able to discuss these confidently will demonstrate your expertise and commitment to compliance.
✨Showcase Your Experience
Prepare to discuss your previous monitoring experience, especially any complex studies you've managed. Highlight specific challenges you faced and how you overcame them, as this will illustrate your problem-solving skills.
✨Emphasise Communication Skills
As a Senior CRA, you'll need to build strong relationships with site personnel. Be ready to provide examples of how you've effectively communicated and collaborated with teams in the past.
✨Express Your Passion for Innovation
Since this role focuses on advanced therapies like CAR-T and gene therapy, express your enthusiasm for these areas. Even if you lack direct experience, showing a genuine interest can set you apart from other candidates.
