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For Companies At a Glance
- Tasks: Conduct site visits, monitor compliance, and mentor junior CRAs.
- Company: Join a leading global CRO trusted by top pharma and biotech firms.
- Benefits: Enjoy flexible home-based work, competitive salary, and career growth.
- Why this job: Make an impact on global studies while maintaining a balanced travel schedule.
- Qualifications: 18-24 months CRA experience, life sciences degree, and strong ICH-GCP knowledge.
- Other info: Opportunity to work in a supportive and collaborative environment.
The predicted salary is between 36000 - 60000 £ per year.
Senior Clinical Research Associate – England
Chloe O\’Shea is proud to partner with a leading global CRO renowned for delivering innovative, high-quality solutions in clinical development. We are seeking an experienced Senior Clinical Research Associate (Senior CRA) to join a dedicated single-sponsor team in England. This is an exciting opportunity to work on cutting-edge studies, with a particular focus on advanced therapy areas such as CAR-T and gene therapy. While prior experience in these fields is highly valued, it is not essential – full training and support will be provided.
The Role
As a Senior CRA, you will be a key contributor to the successful delivery of clinical trials across England. You will oversee site management activities, act as a primary liaison with investigative sites, and ensure strict compliance with protocols, ICH-GCP, and UK regulatory requirements (MHRA/REC). This role is well-suited to ambitious CRAs ready to step up or established Senior CRAs seeking to deepen their expertise in innovative therapy areas.
Key Responsibilities
- Independently manage qualification, initiation, monitoring, and close-out visits across England.
- Ensure high standards of compliance with ICH-GCP, MHRA, REC requirements, and sponsor SOPs.
- Perform source data verification, investigational product accountability, and ensure accurate site documentation.
- Serve as a trusted partner to site personnel, offering training, guidance, and ongoing support.
- Identify site-level challenges proactively and drive timely resolution.
- Contribute to mentorship of junior CRAs and share best practices within the monitoring team.
- Maintain complete and accurate trial documentation in CTMS, eTMF, and EDC systems.
Requirements
- Bachelor\’s degree in Life Sciences, Nursing, Pharmacy, or a related discipline.
- Minimum 3 years of independent UK monitoring experience, ideally with exposure to complex studies.
- Experience in CAR-T and/or gene therapy is highly desirable but not required.
- Strong knowledge of ICH-GCP and UK clinical trial regulations (MHRA/REC).
- Excellent communication, relationship-building, and organisational skills.
What\’s in It for You?
This role offers a competitive salary and benefits package, flexible working arrangements, and clear opportunities for career progression within one of the world\’s largest CROs. You\’ll gain exposure to innovative therapies shaping the future of healthcare, while working in a collaborative culture that values professional development, work-life balance, and wellbeing.
If you are a driven Senior CRA — or an experienced CRA ready to take the next step — we\’d love to hear from you. Apply today to join a global team making a meaningful difference in patients\’ lives.
Senior Clinical Research Associate employer: AL Solutions
Contact Detail:
AL Solutions Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Clinical Research Associate
✨Tip Number 1
Network with professionals in the clinical research field. Attend industry conferences or local meetups to connect with current CRAs and learn about their experiences. This can provide valuable insights and potentially lead to referrals.
✨Tip Number 2
Familiarise yourself with the latest ICH-GCP guidelines and UK regulations. Being well-versed in these areas will not only boost your confidence but also demonstrate your commitment to compliance during interviews.
✨Tip Number 3
Prepare for potential scenario-based questions by reviewing common challenges faced by CRAs. Think about how you would handle site-related issues or mentor junior staff, as this will showcase your problem-solving skills and leadership potential.
✨Tip Number 4
Research the company culture of the CRO you're applying to. Understanding their values and work environment can help you tailor your responses in interviews, showing that you’re a great fit for their team.
We think you need these skills to ace Senior Clinical Research Associate
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights your relevant experience as a Clinical Research Associate. Emphasise your independent monitoring experience, knowledge of ICH-GCP guidelines, and any multi-therapeutic area experience you have.
Craft a Compelling Cover Letter: Write a cover letter that showcases your passion for clinical research and your commitment to advancing human health. Mention specific examples of how you've successfully conducted site visits and maintained compliance in previous roles.
Highlight Key Skills: In your application, clearly outline your communication, organisational, and problem-solving skills. Provide examples of how you've developed strong site relationships and resolved issues in past positions.
Proofread Your Application: Before submitting, carefully proofread your application for any spelling or grammatical errors. A polished application reflects your attention to detail, which is crucial in the role of a Senior Clinical Research Associate.
How to prepare for a job interview at AL Solutions
✨Know Your ICH-GCP Guidelines
Make sure you have a solid understanding of the ICH-GCP guidelines and UK regulations. Be prepared to discuss how you've applied these in your previous roles, as this will demonstrate your expertise and commitment to compliance.
✨Showcase Your Monitoring Experience
Highlight your independent monitoring experience, especially any specific challenges you've faced and how you overcame them. This will help the interviewer see your problem-solving skills in action.
✨Emphasise Relationship Building
Since developing strong site relationships is key, be ready to share examples of how you've successfully built rapport with sites in the past. This shows that you understand the importance of collaboration in clinical research.
✨Prepare for Scenario Questions
Expect scenario-based questions where you might need to identify and resolve site or protocol-related issues. Practising these types of questions can help you articulate your thought process clearly during the interview.
