At a Glance
- Tasks: Explore motor unit properties using AI to improve outcomes for spinal cord injury patients.
- Company: University of Birmingham, a leading research institution in the UK.
- Benefits: Fully funded PhD with stipend, tuition waiver, and allowances for travel and equipment.
- Other info: Join a supportive team and gain valuable clinical training and research networks.
- Why this job: Make a real difference in healthcare through innovative research and advanced technology.
- Qualifications: Strong background in research, medicine, or related fields; Upper Second Class Honours Degree expected.
The predicted salary is between 18622 - 18622 £ per year.
Characterising motor unit properties and behaviours and clinical outcomes using artificial intelligence in humans with spinal cord injury.
University of Birmingham School of Sport, Exercise and Rehabilitation Sciences
About The Project
Full project title: Characterising motor unit properties and behaviours of the paraspinal musculature and clinical outcomes using pattern learning and matching techniques in artificial intelligence in humans with spinal cord injury.
Project Overview
Spinal cord injury (SCI) has significant impact on patients’ physical and psychological well-being. There are an estimated 1.2 million new cases worldwide each year. Such injuries disrupt the communication between the brain and body, causing loss of motor function below the injury. In the early stages following injury, repair processes are extensive in the spinal cord to restore these communication channels. Studies in rodents with SCI showed injury‑induced axonal sprouting and functional recovery. With advanced technology, we are now able to measure axonal sprouting and reinnervation in human SCI using non‑invasive high‑density surface electromyography (HDEMG) system. Paraspinal muscles are directly innervated by the spinal nerves near the spinal cord where the injury is. We hypothesise that properties and behaviours of motor unit action potentials in the paraspinal muscles, assessed via HDEMG, in humans with SCI can reveal the repair processes in the spinal circuits and predict outcomes of recovery.
The project offers research training in a variety of techniques and methods, clinical training, and research networks across institutions nationally and internationally. The supervisory team provides diverse expertise; the host institution is a leading research‑intensive University in the UK. The student will be well supported and developed through the programme.
Person Specification
Applicants should have a strong background in research, and ideally a background in medicine, neuroscience, biomedical sciences, biomedical engineering, or a relevant field. They should have a commitment to research in humans with spinal cord injury and hold or realistically expect to obtain at least an Upper Second Class Honours Degree in a relevant subject. Applicants should have a willingness to travel since data collection from patients with spinal cord injury will take place at partner NHS hospitals. Governance and regulation for working in the NHS will be strictly followed (i.e., enhanced DBS check, occupational health check).
Funding Notes
This is a fully funded studentship provided by the Medical Research Council. If you are successful, you will receive a stipend (currently £18,622 per year for 2023/24) and a tuition fee waiver for 4 years. Successful candidates will also receive an allowance for a laptop, a travel and conference allowance and an allowance for laboratory/PhD running costs.
Bourse doctorale – Birmingham (UK) employer: ACAPS
The University of Birmingham is an exceptional employer, offering a vibrant and inclusive work culture that fosters innovation and collaboration in the field of biomedical research. With access to cutting-edge technology and a supportive supervisory team, PhD candidates will benefit from extensive training and networking opportunities, ensuring their professional growth while contributing to meaningful advancements in spinal cord injury research. Located in the heart of Birmingham, the university provides a dynamic environment for personal and academic development, making it an ideal place for aspiring researchers.
