Scientist II/ Sr Scientist - Protein Mass Spectrometry

We have a vacancy at Scientist II/Senior Scientist level for an analytical expert with mass spectrometry expertise to join our busy Analytics group in Cambridge (UK). In this lab-based role you will be working as part of a team on client-facing projects and will have the opportunity to learn new techniques in a fast-paced and supportive environment.

Overview

Abzena provides integrated early discovery to mid-phase biotherapeutic and ADC drug development services. The Analytics group in Cambridge supports analytical solutions and developments concerning antibody and ADC characterisation, determination of critical quality attributes of biopharmaceuticals, forced degradation stability studies, formulation development, and immuno-peptidomics. The lab is equipped with state-of-the-art instrumentation including triple-quad mass spectrometers, high-resolution Q-TOF, high-sensitivity TOF, Orbitrap mass spectrometers, uHPLC chromatography, capillary electrophoresis, and dynamic light scattering platforms.

We welcome applicants with a PhD or an MSc (or a lower level of qualification with relevant experience) in Protein Chemistry/Biochemistry or a related science discipline, with strong laboratory skills and experience in an industrial or commercial environment. Knowledge and practical experience (including experimental planning, sample preparation, instrument set-up, and data analysis) of quantification and/or characterization techniques for small molecules, biologics, and bioconjugates are core requirements. Experience with N-glycan oligosaccharide profiling would be an asset.

You will be a confident IT user familiar with MS Office and specialist software including Chromeleon, Unifi/MassLynx, Proteome Discoverer, XCalibur and Byos. You will be able to work independently and as part of a team, with good planning and organizing skills, high attention to detail, and the ability to identify, analyse and resolve routine and complex problems. You will be proactive and autonomous, with strong communication skills and the ability to contribute to client projects and discussions in a professional manner. In return, you will receive a competitive salary and benefits package and the opportunity to develop your career in a collaborative, varied, and challenging environment.

Responsibilities

• To design and carry out routine and complex experiments as necessary
• To perform complex/novel techniques under supervision
• To manage own work schedule to ensure tasks are met within the expected timeframe
• To analyse and interpret your own data
• To be responsible for the quality of your own work
• To prepare data for, contribute to the drafting of reports and presentations
• To contribute to internal and client meetings
• To draft and contribute to Quality and Controlled documents
• To undertake any other duties relevant to the position and level

Qualifications

• PhD or MSc (or a lower level of qualification and relevant experience) in Protein Chemistry/Biochemistry or related science with strong laboratory skills and experience in an industrial or commercial environment
• Good understanding of analytics and its application in biotherapeutic drug development
• Knowledge and practical experience in quantification and/or characterization techniques for small molecule, biologics and bioconjugates
• Experience of N-glycan oligosaccharide profiling would be an asset
• MS Office and specialist software including Chromeleon, Unifi/MassLynx, Proteome Discoverer, XCalibur and Byos

UK EEO: Abzena is committed to promoting equal opportunities in employment. All our employees and any job applicants will receive equal treatment regardless of age, disability, gender reassignment, marital or civil partner status, pregnancy or maternity, race, colour, nationality, ethnic or national origin, religion or belief, sex or sexual orientation (“Protected Characteristics”). Please note that this range encompasses both Scientist II and Sr Scientist ranges