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- Tasks: Join us as a Formulation Scientist, preparing and characterising lipid nanoparticles for exciting projects.
- Company: 4basebio is a cutting-edge gene synthesis company focused on innovative DNA solutions for therapies and vaccines.
- Benefits: Enjoy a competitive salary, private healthcare, pension contributions, and life assurance.
- Why this job: Be part of a dynamic team, expand your lab skills, and contribute to impactful research in gene delivery.
- Qualifications: You need at least 2 years of lab experience and a relevant degree in Chemistry or Biochemistry.
- Other info: Located in Cambridge, this role offers a chance to work with multi-disciplinary teams and advance your career.
The predicted salary is between 36000 - 60000 £ per year.
4basebio is an innovative gene synthesis company with the ambition to provide high quality, synthetic DNA for use in gene therapies and gene vaccines. The company is expanding their research and development team at our site in Cambridge, UK to facilitate the scaling of our proprietary DNA manufacturing process, further development of our non-viral platform and AAV vectors for DNA delivery. We are looking for a dynamic and experienced team member to help us achieve our ambitions and goals.
The primary focus of the role is the preparation and characterisation of lipid nanoparticles for client and collaborator projects, in addition to R&D formulation and analytical method development of 4Basebio’s non-viral delivery platform. There will be opportunity for the candidate to interact with multi-disciplinary teams within the research department and expand their laboratory skill set.
Responsibilities:- Preparation and characterisation of lipid nanoparticles for client or collaborator projects
- R&D of non-viral delivery platform: formulation, characterisation and validation of novel nanoparticles for gene delivery based on end needs of the formulations
- Development of novel assays and analytical methods for nanoparticle characterisation
- Execute experiments and be involved in data analysis and interpretation of experimental results
- Actively participate and contribute to laboratory and company meetings
- Maintain an accurate and complete record of laboratory work performed
- To use and maintain company equipment in accordance with the company’s SOPs and health & safety guidelines
- To undertake any other appropriate roles and responsibilities that reasonably fall within the role holder’s skills and experience as requested
- Minimum 2 years practical laboratory experience in relevant scientific field
- BSc, MSc or PhD degree in Chemistry, Biochemistry, biochemical engineering or related discipline
- Experience in nanoparticle production methods (e.g. microfluidics)
- Experience in nanoparticle characterization (e.g. DLS, electron microscopy, HPLC) and downstream process (e.g. purification, sterilization, long-term storage) techniques
- Knowledgeable and/or willingness to discuss molecule level chemistry
- Molecular modelling, chemical synthesis or analytical chemistry knowledge desirable
- Experience in Design of Experiments (DoE) and statistical data analysis is desirable
- An understanding of the basics of gene therapy and nano-scale drug delivery technologies, with an interest in current global development activities and research
- Experience/knowledge on the handling of nucleic acids and related testing techniques (e.g. gel electrophoresis, nucleic acid quantification assay) is desirable
- Great communication and presentation skills
- Self-motivated and willing to learn new skills
- Ability to work in a fast-paced environment and manage multiple projects in parallel
- Must hold the right to work in the UK
- Competitive salary + private healthcare + pension contributions + life assurance
- Location: Over, Cambridge
To apply for this role send your CV and covering letter to Recruitment@4basebio.com. Due to the high number of applicants, if you do not hear back from us within 6 weeks, we thank you for your interest, but please assume you have not been selected for interview on this occasion.
Formulation Scientist employer: 4basebio
Contact Detail:
4basebio Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Formulation Scientist
✨Tip Number 1
Familiarise yourself with the latest advancements in lipid nanoparticle technology. Being able to discuss recent developments or breakthroughs during your interview can demonstrate your passion and knowledge in the field, making you a more attractive candidate.
✨Tip Number 2
Network with professionals in the gene therapy and nanoparticle production sectors. Attend relevant conferences or webinars where you can meet industry experts and potentially get insights into the company culture at 4basebio, which could help you tailor your approach during the interview.
✨Tip Number 3
Prepare to discuss your hands-on experience with nanoparticle characterisation techniques like DLS and electron microscopy. Be ready to provide specific examples of how you've applied these methods in past projects, as this will showcase your practical skills and problem-solving abilities.
✨Tip Number 4
Showcase your ability to work in a fast-paced environment by sharing examples of how you've successfully managed multiple projects simultaneously. This will highlight your organisational skills and adaptability, which are crucial for the dynamic role of a Formulation Scientist.
We think you need these skills to ace Formulation Scientist
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in laboratory work, particularly in nanoparticle production and characterisation. Use specific examples that demonstrate your skills in the areas mentioned in the job description.
Craft a Compelling Cover Letter: In your cover letter, express your enthusiasm for the role and the company. Discuss how your background in chemistry or biochemistry aligns with their goals, and mention any specific projects or experiences that relate to lipid nanoparticles and gene delivery.
Highlight Relevant Skills: Emphasise your experience with analytical methods and techniques such as DLS, electron microscopy, and HPLC. If you have knowledge of molecular modelling or statistical data analysis, make sure to include that as well.
Showcase Your Communication Skills: Since great communication is essential for this role, consider including examples of how you've effectively communicated complex scientific concepts in previous roles or during presentations. This will demonstrate your ability to contribute to multi-disciplinary teams.
How to prepare for a job interview at 4basebio
✨Showcase Your Laboratory Experience
Make sure to highlight your practical laboratory experience, especially in nanoparticle production and characterisation. Be prepared to discuss specific techniques you've used, such as DLS or HPLC, and how they relate to the role.
✨Demonstrate Your Knowledge of Gene Therapy
Familiarise yourself with the basics of gene therapy and nano-scale drug delivery technologies. Showing an understanding of current global developments in this field can set you apart from other candidates.
✨Prepare for Technical Questions
Expect technical questions related to formulation and analytical method development. Brush up on your knowledge of molecular modelling and chemical synthesis, as these may come up during the interview.
✨Emphasise Communication Skills
Since the role involves interacting with multi-disciplinary teams, be ready to demonstrate your communication and presentation skills. Share examples of how you've effectively communicated complex scientific concepts in previous roles.
