Regulatory Affairs Manager

Founded in 2012 by world-renowned plastic and reconstructive surgeon Dr Yannis Alexandrides, 111SKIN is a global skincare brand that bridges the gap between scientific innovation, luxury and community. Beloved by A-listers, high-profile makeup artists, and skincare connoisseurs, 111SKIN is also highly regarded by some of the most reputable editors and industry bodies.

We are looking for a proactive Regulatory Affairs Manager who combines scientific precision with strategic thinking.

What you’ll do:

• Lead 111SKIN’s global regulatory strategy across all markets, ensuring our innovative products meet compliance standards while supporting speed to market.
• Manage complex registration pathways across USA, EU, UK, APAC and mainland China.
• Blend hands-on regulatory work, such as dossier preparation, safety and ingredient review, and claims validation together with strategy to future-proof the brand for evolving global regulations.

What success looks like:

• Ensure 111SKIN’s products are globally compliant, safely formulated, responsibly packaged, and efficiently registered.
• Lead initiatives that strengthen regulatory resilience and enable innovation.

We evaluate each team member based on our three company values: entrepreneurial mindset, caring collaboration, and determination to succeed.

Why you are a great fit:

• You are a meticulous, highly organised professional with a passion for innovation in science-driven skincare.
• You combine strong regulatory knowledge with commercial awareness and strategic foresight.
• You enjoy leading projects that turn complex and changing regulations into clear, actionable frameworks.
• You thrive in a fast-paced, high-growth environment and bring both precision and leadership to your work.

Duties and responsibilities:

• Lead global regulatory strategy across key markets including the UK, EU, USA, APAC and China (NMPA) for cosmetics, supplements, and OTC products.
• Develop and implement a proactive regulatory landscape strategy, ensuring 111SKIN stays ahead of evolving cosmetic, supplement, and OTC regulations.
• Lead regulatory change projects, driving through updates to meet new legislation, industry standards, or internal policy improvements.
• Manage change control processes for raw materials, formulations, packaging components, and artwork updates in coordination with NPD and Operations.
• Prepare and review Product Information Files (PIFs).
• Oversee safety and regulatory documentation for supplements, including label review, claims substantiation, and ingredient checks.
• Manage China Domestic Registration (NMPA) processes, including ingredient screening, documentation coordination, and testing oversight with local partners.
• Review and approve packaging, artwork, and claims to ensure compliance with cosmetic, supplement, and OTC labelling requirements.
• Oversee Extended Producer Responsibility (EPR) and packaging compliance across global regions, ensuring accurate reporting and alignment with sustainability objectives.
• Partner closely with NPD, marketing and operations teams to guide compliant innovation and support global launches across all categories.
• Maintain and update internal regulatory databases, including ingredient restrictions, packaging data, and country-specific requirements.
• Liaise with external consultants, laboratories, and distributors to support compliance and registration activities globally.
• Monitor and interpret global regulatory changes, communicating key insights to internal stakeholders.
• Support internal and external audits, regulatory inspections, and compliance training initiatives.

Requirements:

• 5+ years’ experience in regulatory affairs within cosmetics, ideally skincare.
• Strong understanding of global cosmetic regulations, including EU, UK, US (MoCRA and OTC), and China (NMPA) frameworks.
• Experience reviewing, checking, and approving cosmetic formulations to ensure regulatory compliance and alignment with safety standards.
• Proven experience organising, reviewing, and maintaining Cosmetic Product Safety Reports (CPSRs) and supporting documentation for Product Information Files (PIFs).
• Experience managing OTC drug products (e.g., SPF, acne, or treatment products), including FDA monograph compliance and drug listing submissions.
• Proven experience leading regulatory change initiatives and maintaining change control for formulations, raw materials, and packaging.
• Experience managing Extended Producer Responsibility (EPR) and packaging compliance across international markets.
• Demonstrated experience in claims review for global compliance.
• Familiarity with adverse event reporting and consumer safety surveillance systems.
• Excellent written and verbal communication skills with strong attention to detail and scientific accuracy.
• Highly organised, with the ability to manage multiple projects and deadlines in a dynamic environment.
• Familiarity with systems such as CPNP, SCPN, MoCRA, and the FDA Drug Listing Portal.
• Degree in cosmetic science, chemistry, pharmacy, or a related life sciences field.