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- Tasks: Join us to innovate in bioprocessing, focusing on microbial cultivation and protein expression.
- Company: Constructive Bio is a pioneering biotech start-up transforming cells into bio-renewable factories.
- Benefits: Enjoy private healthcare, generous pension contributions, and on-site parking in a modern office.
- Why this job: Be part of groundbreaking research with significant growth opportunities in a collaborative environment.
- Qualifications: BSc or MSc in relevant fields; practical experience in protein expression and molecular cloning required.
- Other info: Early team members will shape our technology and enjoy meaningful professional development.
The predicted salary is between 36000 - 60000 £ per year.
Constructive Bio is a VC-backed biotechnology start-up based in Whittlesford, Cambridge. Our breakthrough technology harnesses the power of genome rewriting and genetic code reprogramming to make valuable products that positively impact the world. We will use our platform to turn cells into bio-renewable factories to produce novel molecules that were previously inaccessible to natural biology, with diverse applications in industries spanning healthcare, biological research, materials and electronics.
Constructive Bio is a spinout from Professor Jason Chin\’s laboratory at the MRC Laboratory of Molecular Biology in Cambridge. Learn more about the Chin lab achievements here: Chin Lab Achievements
Role Overview
We are looking for an innovative Bioprocess Technician or Associate to join our team. This role represents a critical opportunity to shape cutting-edge biotechnological research, combining technical expertise with creative problem-solving in microbial cultivation, protein expression, and characterisation.
Key Responsibilities
The successful candidate will be responsible for:
- Support scaling up of microbial cultures from flask-based development to larger bioreactor formats.
- Optimising microbial cultivation through precise flask-based fermentation techniques.
- Designing and implementing molecular cloning strategies for novel protein expression.
- Executing protein production and basic purification in bacterial systems (primarily E. coli).
- Performing routine protein characterisation using advanced analytical methods:
- Structural analysis via SDS-PAGE.
- Separation techniques using HPLC.
- Developing and refining microbial growth media.
- Manage cell bank maintenance and validation.
- Maintain meticulous experimental documentation.
- Ensuring rigorous adherence to laboratory health and safety protocols.
Essential Requirements
Candidates must possess:
- BSc or MSc in Biotechnology, Microbiology, Bioprocess based apprenticeship or related scientific discipline.
- Previous practical protein expression experience, ideally with exposure to microbial fermentation techniques.
- Demonstrated proficiency in molecular cloning techniques.
- Strong analytical and problem-solving capabilities.
- Exceptional organisational and communication skills.
- Ability to work autonomously and collaboratively in an interdisciplinary environment.
Desirable Qualifications
Candidates with the following will be particularly competitive:
- Experience or familiarity with bioreactor systems and scale-up procedures.
- Familiarity with chromatography equipment.
- Proven Design of Experiment (DoE) methodology skills.
- Industrial biotechnology background.
Constructive Bio is a rapidly growing biotechnology start-up near Cambridge, offering an exciting opportunity to join our bioprocess team and contribute to innovative scientific research. Significant growth opportunities exist both within our small bioprocess team and across the broader company. Based in modern Whittlesford offices, we provide competitive benefits including private healthcare, generous pension contributions, and on-site parking. Early team members will experience meaningful professional development, helping to shape our technological platform in a collaborative environment where individual contributions are valued.
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Bioprocess Research Associate employer: Constructive Bio
Contact Detail:
Constructive Bio Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Bioprocess Research Associate
✨Tip Number 1
Familiarise yourself with the latest advancements in microbial fermentation techniques. This will not only help you understand the role better but also allow you to engage in meaningful conversations during interviews, showcasing your passion and knowledge about the field.
✨Tip Number 2
Network with professionals in the biotechnology sector, especially those who have experience in bioprocessing or microbial cultivation. Attend relevant conferences or webinars to connect with industry experts and gain insights that could give you an edge in your application.
✨Tip Number 3
Prepare to discuss specific examples of your previous work with protein expression and molecular cloning. Being able to articulate your hands-on experience and problem-solving skills will demonstrate your suitability for the role and your ability to contribute to the team.
✨Tip Number 4
Research Constructive Bio's recent projects and achievements, particularly those related to genome rewriting and genetic code reprogramming. Showing that you are informed about their work will reflect your genuine interest in the company and its mission.
We think you need these skills to ace Bioprocess Research Associate
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in biotechnology, microbiology, and bioprocessing. Emphasise any practical skills you have in protein expression and microbial fermentation techniques.
Craft a Compelling Cover Letter: Write a cover letter that showcases your passion for biotechnology and your understanding of Constructive Bio's mission. Mention specific experiences that align with the responsibilities outlined in the job description.
Highlight Technical Skills: In your application, clearly outline your technical skills related to molecular cloning, protein characterisation, and any experience with bioreactor systems. Use specific examples to demonstrate your proficiency.
Showcase Problem-Solving Abilities: Provide examples in your application that illustrate your analytical and problem-solving capabilities. Discuss how you've approached challenges in previous roles and the outcomes of your efforts.
How to prepare for a job interview at Constructive Bio
✨Showcase Your Technical Skills
Be prepared to discuss your hands-on experience with microbial fermentation techniques and protein expression. Highlight specific projects where you successfully applied these skills, as this will demonstrate your practical knowledge and problem-solving abilities.
✨Understand the Company’s Technology
Familiarise yourself with Constructive Bio's technology and its applications in biotechnology. Being able to discuss how genome rewriting and genetic code reprogramming work will show your genuine interest in the company and its mission.
✨Prepare for Scenario-Based Questions
Expect questions that assess your analytical and problem-solving capabilities. Prepare examples of past challenges you've faced in bioprocessing or microbial cultivation, and explain how you approached and resolved them.
✨Emphasise Team Collaboration
Since the role requires working in an interdisciplinary environment, be ready to share experiences where you collaborated effectively with others. Highlight your communication skills and how you contribute to a team dynamic.
