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- Tasks: Design and develop biophysical assays to characterise cancer targets and advance novel treatments.
- Company: Proclinical is a leading life sciences recruiter connecting talent with top global positions.
- Benefits: Enjoy a dynamic work environment, collaboration opportunities, and the chance to impact cancer research.
- Why this job: Join a passionate team driving therapeutic innovation and shaping the future of science.
- Qualifications: Background in biophysics or related field; expertise in biophysical methods required.
- Other info: Opportunity to collaborate with industry leaders and contribute to groundbreaking cancer therapies.
The predicted salary is between 48000 - 72000 £ per year.
Job Description
Where curiosity meets purpose-join us in shaping the future of science.
Proclinical is seeking a Principal Biophysicist/Biophysical Scientist to join a dynamic Drug Discovery team based in Cambridge, UK. This role focuses on designing and developing biophysical assays to characterize cancer targets at the molecular level, with the goal of advancing novel cancer treatments. You will play a key role in implementing innovative technologies and collaborating with industry and academic partners to drive therapeutic innovation.
Responsibilities:
- Design and develop physiologically relevant biophysical assays to characterize cancer targets.
- Profile structure-binding and structure-kinetic relationships of small molecules and antibodies.
- Characterize mechanisms of action to inform dose prediction and clinical efficacy.
- Stay updated on cutting-edge biophysical techniques and implement new technologies.
- Lead assay development for a range of target classes.
- Provide scientific leadership and strategic direction within the Drug Discovery team.
- Collaborate with internal teams and external partners to progress projects from idea to pre-clinical candidate.
Key Skills and Requirements:
- Background in biophysics or a related discipline (BSc, MSc, or PhD preferred; relevant experience may substitute for education).
- Expertise in dissecting enzyme and small molecule inhibitor mechanisms using biophysical methods.
- Practical experience with established biophysical techniques such as SPR, ITC, MST, and DSF-TSA.
- Familiarity with emerging technologies like GCI and Spectral Shift.
- Proven track record in assay development across various target classes.
- Strong scientific leadership skills and ability to provide strategic direction.
- Recognized external reputation through publications, conference presentations, or professional networks.
If you are having difficulty in applying or if you have any questions, please contact Ruhee Saleh at r.saleh@proclinical.com.
Apply Now:
If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists please request a call back at the top of this page.
Proclinical is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Proclinical is acting as an Employment Agency in relation to this vacancy.
By submitting this application, you confirm that you've read and understood our privacy policy, which informs you how we process and safeguard your data – https://www.proclinical.com/privacy-policy
Principal Biophysicist/Biophysical Scientist employer: Proclinical Staffing
Contact Detail:
Proclinical Staffing Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Principal Biophysicist/Biophysical Scientist
✨Tip Number 1
Network with professionals in the biophysics and drug discovery fields. Attend relevant conferences or seminars where you can meet industry leaders and potential colleagues. This can help you gain insights into the latest trends and technologies, making you a more attractive candidate.
✨Tip Number 2
Stay updated on the latest biophysical techniques and emerging technologies. Familiarise yourself with methods like GCI and Spectral Shift, as well as established techniques such as SPR and ITC. Demonstrating your knowledge of these tools during interviews can set you apart from other candidates.
✨Tip Number 3
Engage with the scientific community by publishing your research or presenting at conferences. Building a strong external reputation can enhance your credibility and show that you are an active contributor to the field, which is highly valued in roles like this.
✨Tip Number 4
Prepare to discuss your experience in assay development and how it relates to cancer targets. Be ready to provide specific examples of your work and the impact it had on previous projects. This will demonstrate your capability to lead and innovate within the Drug Discovery team.
We think you need these skills to ace Principal Biophysicist/Biophysical Scientist
Some tips for your application 🫡
Understand the Role: Before applying, make sure you fully understand the responsibilities and requirements of the Principal Biophysicist/Biophysical Scientist position. Tailor your application to highlight how your skills and experiences align with the job description.
Highlight Relevant Experience: In your CV and cover letter, emphasise your background in biophysics or related disciplines. Include specific examples of your expertise in biophysical methods and any relevant projects you've worked on, especially those related to cancer research.
Showcase Leadership Skills: Since the role requires strong scientific leadership, be sure to mention any experience you have in leading teams or projects. Provide examples of how you've contributed to strategic direction in previous roles.
Craft a Compelling Cover Letter: Your cover letter should not only express your interest in the position but also demonstrate your understanding of the company's mission and how you can contribute to their goals in drug discovery. Make it personal and engaging to stand out.
How to prepare for a job interview at Proclinical Staffing
✨Showcase Your Technical Expertise
Be prepared to discuss your experience with biophysical techniques such as SPR, ITC, MST, and DSF-TSA. Highlight specific projects where you successfully implemented these methods to characterise cancer targets.
✨Demonstrate Leadership Skills
Since the role requires scientific leadership, think of examples where you've led a team or project. Discuss how you provided strategic direction and collaborated with others to achieve goals.
✨Stay Updated on Emerging Technologies
Familiarity with new technologies like GCI and Spectral Shift is crucial. Be ready to talk about recent advancements in biophysics and how you plan to integrate them into your work.
✨Prepare for Collaborative Scenarios
Collaboration is key in this role. Think of instances where you've worked with internal teams or external partners. Be ready to discuss how you navigated challenges and contributed to successful outcomes.
