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- Tasks: Join a dynamic lab to research cancer cell interactions and therapeutic responses.
- Company: Be part of the Cancer Research UK Manchester Institute, a leader in cancer research.
- Benefits: Enjoy a competitive salary, innovative environment, and collaboration with top cancer treatment centres.
- Why this job: Make a real impact in cancer research while working with cutting-edge technology and a supportive team.
- Qualifications: PhD in relevant fields; experience in cancer biology and cell signalling is essential.
- Other info: Fixed term until February 2027; apply by 6 July 2025.
The predicted salary is between 31000 - 37000 £ per year.
Postdoctoral Scientists – Systems Oncology Group
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Postdoctoral Scientists – Systems Oncology Group
Cancer Research UK Manchester Institute
1299 12420
- Deadline:
06 July 2025 £37,000 to £44,852 depending on qualifications
and experience Click here to visit website Contact:
Claus Jorgensen
Email Now Visit Website Back to Results
• Job Ref: MI/25/33
• Salary starting: £37,000 – £44,852 (depending on qualifications and experience)
• Duration: Fixed term until 28 February 2027
About the role:
Dr Claus Jorgensen, Group Leader of the Systems Oncology Group, is looking for a Postdoctoral Scientist to join his group. This is a great opportunity for a self-motivated, innovative, meticulous and organised candidate who is keen to work in a dynamic laboratory undertaking cutting edge research.
The goal of the Systems Oncology Group is to understand how the tumour microenvironment, and the desmoplastic reaction, regulates tumour cell function and therapeutic response in pancreatic ductal adenocarcinoma. We have identified a novel target regulating the interactions between tumour cells and the microenvironment, which we believe may be a target for future therapeutic intervention.
The objective of this post is to functionally characterise this target and its role in regulating tumour cells, host cells, and their interactions. Specifically, the post holder will use a number of in vitro cell biology assays to assess cell function and biochemical assays to assess cell signalling in vitro; this will include functional CRISPR screening and mass spectrometry analysis in 2D and 3D cell models. Tumour models will be analysed by IF/IHC, proteomics, genomics and transcriptionally as well as testing novel combination treatments using available in vivo models (see Hutton et al Cancer Cell 2021, Lee et al Nat Comm 2021 and Below et al Nat Mat 2022). This is a project for a highly collaborative individual seeking to make a difference in a very hard to treat cancer.
About you:
You should have a PhD in biochemistry, cancer biology, cell biology, immunology or a related field. Experience in protein biochemistry, analysis of cell signalling and use of in vitro models of cancer is required. Experience with in vivo tumour models and immunology is desirable. Key qualities include independent thinking, ability to work in a team and good communication skills, all of which are needed to efficiently work in a multidisciplinary team.
Why choose Cancer Research UK Manchester Institute?
The Cancer Research UK Manchester Institute (www.cruk.manchester.ac.uk ), an Institute of The University of Manchester (www.manchester.ac.uk ), is a world-leading centre for excellence in cancer research. The Institute is core funded by Cancer Research UK (www.cancerresearchuk.org ), the largest independent cancer research organisation in the world. In spring 2023 the Institute moved into the new Paterson Building, a £150 million flagship purpose-built biomedical research centre directly attached to The Christie NHS Foundation Trust (www.christie.nhs.uk ), in South Manchester.
We are partnered with The Christie NHS Foundation Trust, one of the largest cancer treatment centres in Europe. These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.
How to apply?
To apply for this position please visit our website:
https://www.cruk.manchester.ac.uk/careers/
Informal enquiries can be directed to Dr Claus Jorgensen via email: claus.jorgensen@cruk.manchester.ac.uk .
Closing date: Sunday 6 July 2025
1st round interviews w.c. 21 July 2025 Email Now Visit Website Back to Results
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Recipient: Claus Jorgensen
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Postdoctoral Scientists - Systems Oncology Group employer: Findauniversity Ltd.
Contact Detail:
Findauniversity Ltd. Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Postdoctoral Scientists - Systems Oncology Group
✨Tip Number 1
Network with current and former members of the Systems Oncology Group. Reach out on platforms like LinkedIn to learn about their experiences and gather insights that could help you during the interview process.
✨Tip Number 2
Familiarise yourself with the latest research published by the group, especially the papers mentioned in the job description. Being able to discuss these studies and their implications will demonstrate your genuine interest and knowledge during interviews.
✨Tip Number 3
Prepare to showcase your technical skills relevant to the role, such as CRISPR screening and mass spectrometry. Consider setting up a mock presentation to explain your past projects and how they relate to the work at the Systems Oncology Group.
✨Tip Number 4
Highlight your collaborative experiences in previous roles. Since this position requires working in a multidisciplinary team, be ready to share specific examples of how you've successfully collaborated with others in research settings.
We think you need these skills to ace Postdoctoral Scientists - Systems Oncology Group
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in biochemistry, cancer biology, and cell biology. Emphasise any specific projects or research that align with the Systems Oncology Group's focus on tumour microenvironments and therapeutic responses.
Craft a Strong Cover Letter: In your cover letter, express your enthusiasm for the role and the research being conducted by Dr Claus Jorgensen. Discuss how your skills and experiences make you a suitable candidate for this position, particularly your experience with in vitro models and cell signalling.
Highlight Collaborative Skills: Since the role requires working in a multidisciplinary team, be sure to mention any previous collaborative projects. Provide examples of how you effectively communicated and worked with others to achieve common goals in your past research.
Follow Application Instructions: Ensure you apply through the Cancer Research UK Manchester Institute's website as specified. Double-check that all required documents are included and that your application is submitted before the deadline of 6 July 2025.
How to prepare for a job interview at Findauniversity Ltd.
✨Know Your Research
Familiarise yourself with the latest research in systems oncology, particularly related to pancreatic ductal adenocarcinoma. Be prepared to discuss how your previous work aligns with the goals of the Systems Oncology Group and demonstrate your understanding of the tumour microenvironment.
✨Showcase Your Skills
Highlight your experience in protein biochemistry, cell signalling, and in vitro cancer models during the interview. Be ready to provide specific examples of your past projects and how they relate to the techniques mentioned in the job description, such as CRISPR screening and mass spectrometry.
✨Emphasise Collaboration
Since this role requires working in a multidisciplinary team, be sure to convey your ability to collaborate effectively. Share examples of past teamwork experiences and how you contributed to achieving common goals, especially in a research setting.
✨Prepare Thoughtful Questions
Prepare insightful questions about the Systems Oncology Group's current projects and future directions. This shows your genuine interest in the role and helps you assess if the position aligns with your career aspirations.
