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For Companies At a Glance
- Tasks: Lead large-scale molecular genetic experiments and collaborate with data scientists.
- Company: Join a rapidly growing biotech company making a positive impact on patients' lives.
- Benefits: Opportunity to supervise a team and develop a broad range of skills.
- Why this job: Be part of an exceptional team and shape the company's culture and strategic direction.
- Qualifications: PhD with 3+ years of experience in academia, biotech, or pharma required.
- Other info: Hands-on experience with CRISPR/Cas genome-editing is essential.
The predicted salary is between 48000 - 84000 £ per year.
The Opportunity
We have an exciting opportunity for a talented Senior Scientist to contribute intellectually and experimentally to this endeavour. By joining, you will be part of an exceptionally talented team, gain exposure to a broad range of skills beyond your area of expertise, help shape our culture and strategic direction, and ultimately, make a positive impact on patients’ lives. As the company grows rapidly, there may be opportunities to supervise a small team.
Your Responsibilities
• Contribute intellectually and experimentally to the design and execution of large-scale molecular genetic experiments, including cell model characterisation, assay optimisation, and high-throughput screening.
• Develop, optimise, and implement functional assays to investigate gene function in disease-relevant contexts, with a focus on endothelial and fibroblast biology.
• Work closely with data scientists to develop robust data analysis pipelines.
• Contribute to the biological interpretation of screen hits and drive target validation efforts.
• Stay abreast of new gene-editing technologies and methodologies.
• Support laboratory operations in a start-up environment, contributing to shared responsibilities such as tissue culture maintenance and equipment upkeep.
Professionally, you have
• A PhD with at least 3 years of additional experience in academia, biotech, or pharma.
• Expertise in high-throughput cell assay development, including adherent and suspension cells.
• Strong experience in functional assays related to either endothelial OR fibroblast biology, specifically:
- Endothelial cell functional assays, including angiogenesis, EndoMT (Endothelial-to-Mesenchymal Transition), and tube formation assays.
- Fibroblast functional assays, including extracellular matrix (ECM) deposition and contraction assays.
• Experience leading the day-to-day operations of large-scale genetic or chemical screens in arrayed and/or pooled formats.
• At least two years of hands-on experience applying the latest CRISPR/Cas genome-editing approaches, including nucleofection and/or lentiviral transductions.
• Proven ability to deliver results within tight timelines.
Desirable:
• Experience with liquid handling, automation, FACS, and/or automated high-content microscopy.
• Experience working in interdisciplinary teams, particularly with computational scientists.
• Broad expertise in molecular biology, including molecular cloning.
Your Attributes
• Excellent attention to detail, analytical and critical thinking skills.
• Strong team-working abilities and effective communication with scientists across disciplines.
• Self-motivated with an inquisitive nature and eagerness to learn.
• Ability to work in a fast-paced, data-driven environment with shifting priorities.
• Willingness to contribute to operational aspects of a growing laboratory.
Senior Scientist- Genomics employer: Hlx Life Sciences
Contact Detail:
Hlx Life Sciences Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Scientist- Genomics
✨Tip Number 1
Make sure to highlight your hands-on experience with CRISPR/Cas genome-editing techniques during networking opportunities. Engaging in discussions about your practical applications of these technologies can set you apart from other candidates.
✨Tip Number 2
Connect with professionals in the biotech and pharma industries through platforms like LinkedIn. Join relevant groups and participate in discussions to showcase your expertise and interest in high-throughput screening and molecular genetic experiments.
✨Tip Number 3
Stay updated on the latest advancements in gene editing technologies by attending webinars, workshops, or conferences. This not only enhances your knowledge but also provides great talking points during interviews.
✨Tip Number 4
Consider reaching out to current or former employees of our company to gain insights into the team culture and expectations. This can help you tailor your approach and demonstrate your genuine interest in contributing to our mission.
We think you need these skills to ace Senior Scientist- Genomics
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights your relevant experience in high-throughput cell assay development and CRISPR/Cas genome-editing. Use specific examples that demonstrate your expertise and achievements in these areas.
Craft a Compelling Cover Letter: In your cover letter, express your passion for genomics and how your background aligns with the company's mission. Mention your experience in leading genetic screens and working collaboratively with data scientists.
Showcase Your Research Experience: Detail your hands-on research experience, especially any projects involving T cell, fibroblast, or other relevant assays. Highlight any interdisciplinary collaborations that showcase your ability to work with computational scientists.
Highlight Your Problem-Solving Skills: Provide examples of how you've successfully delivered results under tight timelines. This will demonstrate your ability to thrive in a fast-paced, start-up laboratory environment.
How to prepare for a job interview at Hlx Life Sciences
✨Showcase Your Expertise
Be prepared to discuss your experience with high-throughput cell assay development and CRISPR/Cas genome-editing approaches. Highlight specific projects where you successfully applied these techniques, as this will demonstrate your hands-on expertise.
✨Demonstrate Team Collaboration
Since the role involves working closely with data scientists, share examples of past interdisciplinary collaborations. Discuss how you effectively communicated and contributed to team goals, showcasing your ability to work in a dynamic environment.
✨Stay Updated on Technologies
Research the latest advancements in gene editing technologies and methodologies. Being able to discuss recent developments or innovations during the interview will show your commitment to staying at the forefront of the field.
✨Prepare for Problem-Solving Questions
Expect questions that assess your ability to deliver results under tight timelines. Prepare examples of challenges you've faced in previous roles and how you overcame them, particularly in the context of large-scale experiments.
