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- Tasks: Lead CHO cell line projects and optimise cell lines using advanced techniques.
- Company: Join a dynamic biopharma team in Oxford focused on innovative biologics manufacturing.
- Benefits: Enjoy a competitive salary, generous holidays, pension scheme, and ongoing training.
- Why this job: Be part of a cutting-edge team shaping the future of biotherapeutics with impactful work.
- Qualifications: PhD or MSc in relevant fields with 5+ years of CHO cell line development experience required.
- Other info: This is a full-time, permanent role with opportunities for growth and collaboration.
The predicted salary is between 48000 - 84000 £ per year.
We’re hiring a skilled Cell Line Development Scientist to join a fast-paced biopharma team in Oxford. This full-time, permanent role offers the chance to lead CHO cell line projects supporting early-stage biologics manufacturing. You’ll play a key part in engineering and optimizing cell lines using cutting-edge techniques like CRISPR/Cas9 and miniature bioreactors (ambr15), contributing from design through to early clinical production.
About the Role
As a Scientist in the Cell Line Development group, you’ll drive projects focused on CHO cell engineering, stability assessment, and clone selection. You’ll collaborate with analytical and process development teams, manage key experiments, and help shape the future of biotherapeutic production.
Key Responsibilities
- Develop and characterize CHO cell lines for biologic production.
- Design gene editing strategies (e.g., CRISPR/Cas9) to enhance cell performance.
- Conduct transfections, single cell cloning, and clone screening.
- Run stability studies and guide Cell Bank generation.
- Operate miniature (ambr15) and small-scale bioreactors for process evaluation.
- Accurately analyze and report experimental data.
- Collaborate across functions to meet project goals.
- Ensure biosafety and quality compliance.
About You
- PhD or MSc in Cell Biology, Biotechnology, Biochemical Engineering or related field.
- 5+ years of hands-on experience in CHO cell line development (biopharma or CDMO preferred).
- Strong skills in CHO cultivation, gene editing, and bioreactor operation.
- Experience with CRISPR/Cas9, transfection, and clone selection workflows.
- Familiarity with regulatory-compliant stability testing and Cell Bank generation.
- Proficiency in data analysis, electronic lab notebooks, and biopharma software tools.
- Strong communication and organizational skills; leadership experience is a plus.
Salary & Benefits
- Competitive salary with bonus
- Generous holiday allowance and pension scheme
- Comprehensive benefits package
- Ongoing training and development
- Based in Oxford
Ready to Apply? If you bring the experience and enthusiasm to make an impact in this role, we’d love to hear from you. Apply now to be part of a growing and innovative team shaping the future of biotherapeutics.
Cell Line Development Scientist employer: Cranleigh STEM, Sustainability & SHEQ Recruitment
Contact Detail:
Cranleigh STEM, Sustainability & SHEQ Recruitment Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Cell Line Development Scientist
✨Tip Number 1
Network with professionals in the biopharma industry, especially those who have experience in CHO cell line development. Attend relevant conferences or workshops to meet potential colleagues and learn about the latest trends and techniques.
✨Tip Number 2
Familiarise yourself with the specific technologies mentioned in the job description, such as CRISPR/Cas9 and ambr15 bioreactors. Consider online courses or webinars that focus on these areas to enhance your practical knowledge.
✨Tip Number 3
Prepare to discuss your previous projects in detail during interviews. Highlight your hands-on experience with CHO cell line development and any leadership roles you've taken on, as this will demonstrate your capability to drive projects effectively.
✨Tip Number 4
Showcase your collaborative skills by providing examples of how you've worked with cross-functional teams in the past. This is crucial for the role, so be ready to explain how you can contribute to a team-oriented environment.
We think you need these skills to ace Cell Line Development Scientist
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights your relevant experience in CHO cell line development, gene editing techniques like CRISPR/Cas9, and any hands-on work with bioreactors. Use specific examples to demonstrate your skills and achievements.
Craft a Compelling Cover Letter: In your cover letter, express your enthusiasm for the role and the company. Discuss how your background aligns with the key responsibilities mentioned in the job description, particularly your experience in cell line engineering and collaboration across teams.
Highlight Key Skills: Emphasise your strong skills in CHO cultivation, data analysis, and regulatory compliance. Mention any leadership experience you have, as this could set you apart from other candidates.
Proofread Your Application: Before submitting, carefully proofread your application materials for any spelling or grammatical errors. A polished application reflects your attention to detail and professionalism, which are crucial in a scientific role.
How to prepare for a job interview at Cranleigh STEM, Sustainability & SHEQ Recruitment
✨Showcase Your Technical Skills
Be prepared to discuss your hands-on experience with CHO cell line development, CRISPR/Cas9 techniques, and bioreactor operations. Highlight specific projects where you successfully engineered or optimised cell lines, as this will demonstrate your expertise and relevance to the role.
✨Prepare for Scenario-Based Questions
Expect questions that assess your problem-solving abilities in real-world scenarios. Think of examples where you had to troubleshoot issues during cell line development or how you approached stability studies. This will show your analytical skills and ability to work under pressure.
✨Emphasise Collaboration Experience
Since the role involves working with various teams, be ready to discuss your experience in cross-functional collaboration. Share examples of how you’ve worked with analytical and process development teams to achieve project goals, showcasing your teamwork and communication skills.
✨Demonstrate Your Passion for Biopharma
Express your enthusiasm for the biopharmaceutical industry and your commitment to advancing biotherapeutics. Discuss any recent developments in the field that excite you and how you see yourself contributing to the company's mission and growth.
