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- Tasks: Lead CHO cell line projects and optimise cell lines using cutting-edge techniques.
- Company: Join a fast-paced biopharma team in Oxford focused on innovative biologics manufacturing.
- Benefits: Enjoy a competitive salary, generous holiday, pension scheme, and ongoing training.
- Why this job: Be part of a growing team shaping the future of biotherapeutics with impactful work.
- Qualifications: PhD or MSc in relevant fields with 5+ years of CHO cell line development experience.
- Other info: Collaborate across functions and ensure compliance while working with advanced technologies.
The predicted salary is between 43200 - 72000 £ per year.
We’re hiring a skilled Cell Line Development Scientist to join a fast-paced biopharma team in Oxford. This full-time, permanent role offers the chance to lead CHO cell line projects supporting early-stage biologics manufacturing. You’ll play a key part in engineering and optimizing cell lines using cutting-edge techniques like CRISPR/Cas9 and miniature bioreactors (ambr15), contributing from design through to early clinical production.
As a Scientist in the Cell Line Development group, you’ll drive projects focused on CHO cell engineering, stability assessment, and clone selection. You’ll collaborate with analytical and process development teams, manage key experiments, and help shape the future of biotherapeutic production.
Key Responsibilities- Develop and characterize CHO cell lines for biologic production.
- Design gene editing strategies (e.g., CRISPR/Cas9) to enhance cell performance.
- Conduct transfections, single cell cloning, and clone screening.
- Run stability studies and guide Cell Bank generation.
- Operate miniature (ambr15) and small-scale bioreactors for process evaluation.
- Accurately analyze and report experimental data.
- Collaborate across functions to meet project goals.
- Ensure biosafety and quality compliance.
- PhD or MSc in Cell Biology, Biotechnology, Biochemical Engineering or related field.
- 5+ years of hands-on experience in CHO cell line development (biopharma or CDMO preferred).
- Strong skills in CHO cultivation, gene editing, and bioreactor operation.
- Experience with CRISPR/Cas9, transfection, and clone selection workflows.
- Familiarity with regulatory-compliant stability testing and Cell Bank generation.
- Proficiency in data analysis, electronic lab notebooks, and biopharma software tools.
- Strong communication and organizational skills; leadership experience is a plus.
- Competitive salary with bonus
- Generous holiday allowance and pension scheme
- Comprehensive benefits package
- Ongoing training and development
- Based in Oxford
If you bring the experience and enthusiasm to make an impact in this role, we’d love to hear from you. Apply now to be part of a growing and innovative team shaping the future of biotherapeutics.
Cell Line Development Scientist employer: Cranleigh STEM, Sustainability & SHEQ Recruitment
Contact Detail:
Cranleigh STEM, Sustainability & SHEQ Recruitment Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Cell Line Development Scientist
✨Tip Number 1
Network with professionals in the biopharma industry, especially those working in cell line development. Attend relevant conferences or webinars to connect with potential colleagues and learn about the latest trends and techniques.
✨Tip Number 2
Familiarise yourself with the specific technologies mentioned in the job description, such as CRISPR/Cas9 and ambr15 bioreactors. Consider hands-on workshops or online courses to enhance your practical skills in these areas.
✨Tip Number 3
Prepare to discuss your previous experiences in CHO cell line development during interviews. Be ready to share specific examples of projects you've led or contributed to, highlighting your problem-solving skills and results.
✨Tip Number 4
Showcase your collaborative skills by preparing examples of how you've worked with cross-functional teams in the past. Emphasise your ability to communicate effectively and drive projects towards successful outcomes.
We think you need these skills to ace Cell Line Development Scientist
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights your relevant experience in CHO cell line development, gene editing techniques like CRISPR/Cas9, and any hands-on work with bioreactors. Use specific examples to demonstrate your skills and achievements.
Craft a Compelling Cover Letter: In your cover letter, express your enthusiasm for the role and the company. Mention how your background aligns with the key responsibilities outlined in the job description, particularly your experience in cell line engineering and collaboration across teams.
Showcase Your Technical Skills: Be sure to include any specific technical skills that are relevant to the position, such as proficiency in data analysis, experience with electronic lab notebooks, and familiarity with regulatory compliance in biopharma settings.
Proofread Your Application: Before submitting, carefully proofread your application materials for any spelling or grammatical errors. A polished application reflects your attention to detail and professionalism, which is crucial in a scientific role.
How to prepare for a job interview at Cranleigh STEM, Sustainability & SHEQ Recruitment
✨Showcase Your Technical Skills
Be prepared to discuss your hands-on experience with CHO cell line development, CRISPR/Cas9 techniques, and bioreactor operations. Highlight specific projects where you successfully engineered or optimised cell lines, as this will demonstrate your expertise and relevance to the role.
✨Prepare for Scenario-Based Questions
Expect questions that assess your problem-solving abilities in real-world scenarios. Think about challenges you've faced in previous roles, particularly related to gene editing or clone selection, and be ready to explain how you approached and resolved these issues.
✨Emphasise Collaboration Skills
Since the role involves working closely with analytical and process development teams, be sure to highlight your teamwork experiences. Share examples of successful collaborations and how you contributed to achieving project goals, showcasing your ability to work across functions.
✨Demonstrate Your Passion for Biotherapeutics
Express your enthusiasm for the field of biopharma and your commitment to advancing biotherapeutic production. Discuss any ongoing training or professional development you've pursued, as well as your vision for the future of cell line development, to show that you're not just qualified but also genuinely interested in the industry.
