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- Tasks: Lead the transition of oncology assets into First-in-Human clinical trials.
- Company: Join a pioneering biotech firm revolutionising cancer treatment with innovative ADC technology.
- Benefits: Enjoy competitive salary, stock options, healthcare package, pension, and more perks.
- Why this job: Be part of a mission-driven team shaping early clinical development strategies in a cutting-edge environment.
- Qualifications: Advanced degree in relevant fields with proven expertise in translational science for biologics.
- Other info: Hybrid work model available; collaborate with top industry experts and drive impactful change.
The predicted salary is between 43200 - 72000 £ per year.
Apsida Life Science is currently partnering with a pioneering, well-funded pre-clinical biotech company at the forefront of Antibody Drug Conjugate (ADC) technology. This organization offers a rare opportunity to lead the transition of their lead oncology asset into First-in-Human (FIH) clinical trials. With a leadership team comprising top industry experts and a cutting-edge platform designed to address unmet medical needs, this company provides an ideal environment for individuals eager to play a key role in shaping early clinical development strategies. Their mission is focused on transforming cancer treatment through novel bispecific ADC solutions, supported by robust funding and innovative discovery platforms.
Responsibilities:
- Develop and implement translational science strategies that align with the "5 Rs" framework (right targets, right safety, right tissue, right patient, right commercial opportunity) for multispecific ADC programs.
- Design and interpret studies focused on payload mechanisms, linker stability, and target-mediated distribution.
- Guide preclinical development relating to internalization kinetics, lysosomal trafficking, and bystander effect modeling.
- Oversee PK/PD modeling, biomarker development, and assay strategies to ensure IND readiness.
- Support indication selection through integration of expression data, tumor biology insights, and competitive landscape analysis.
- Contribute to patient enrichment strategies using biomarker-driven approaches.
- Collaborate with external consultants on protocol development, dose selection rationale, and clinical site strategy.
- Engage with KOLs, advisors, and regulatory bodies to drive program success.
- Represent translational and early clinical insights to stakeholders including investors and business development partners.
- Shape scientific positioning and pipeline narrative alongside senior leadership.
Qualifications:
Essential:
- Advanced degree (PhD + 5 years or BSc/MSc + 10 years) in Oncology, Immunology, Pharmacology, or related fields.
- Proven expertise in steering translational science strategy for biologics into Phase 1 trials.
- Strong background in PK/PD modeling, biomarker strategy, and mechanism of action studies.
- Deep experience in ADC development including payload selection, toxicity assessment, and tissue penetration modeling.
- Familiarity with IND preparation and early clinical trial design.
Desirable:
- Experience with non-clinical models (PDX, CDX) for efficacy and biodistribution studies.
- Integration of multi-omics or spatial data for patient/indication selection.
- Participation in successful IND filings and FIH ADC programs.
Package:
- Competitive Salary
- Stock Options
- Healthcare Package
- Pension + Additional Benefits
If you are interested in learning more, please reach out to Finley Lenihan at Apsida Life Science: finley.lenihan@apsida.com www.apsida.co.uk +44 (0) 203 854
Apsida Life Science is a specialist recruitment business based in London (UK), Redhill (UK), Boston (USA), & Pretoria (South Africa), dedicated to delivering top talent to the Life Science industry. We pride ourselves on offering a high-quality, trusted service that places the candidate journey at the core of every process.
Associate Director of Translational Sciences employer: Apsida Life Science
Contact Detail:
Apsida Life Science Recruiting Team
finley.lenihan@apsida.com
StudySmarter Expert Advice 🤫
We think this is how you could land Associate Director of Translational Sciences
✨Tip Number 1
Network with professionals in the biotech and pharmaceutical industries, especially those who have experience with Antibody Drug Conjugates (ADCs). Attend relevant conferences or webinars to connect with key opinion leaders (KOLs) and potential colleagues who can provide insights into the role and company culture.
✨Tip Number 2
Familiarise yourself with the latest advancements in ADC technology and translational science strategies. Being well-versed in current trends and challenges will not only help you during interviews but also demonstrate your genuine interest in the field and the company's mission.
✨Tip Number 3
Prepare to discuss specific examples from your past experiences that align with the responsibilities of the role. Highlight your expertise in PK/PD modelling, biomarker strategy, and any successful IND filings you've been involved in to showcase your qualifications effectively.
✨Tip Number 4
Engage with the company’s online presence, such as their website and social media channels. Understanding their recent projects and achievements can provide valuable talking points during interviews and show your enthusiasm for joining their team.
We think you need these skills to ace Associate Director of Translational Sciences
Some tips for your application 🫡
Understand the Role: Thoroughly read the job description for the Associate Director of Translational Sciences position. Make sure you understand the responsibilities and qualifications required, especially the focus on ADC technology and translational science strategies.
Tailor Your CV: Customise your CV to highlight relevant experience in oncology, immunology, or pharmacology. Emphasise your expertise in PK/PD modelling, biomarker strategy, and any previous work with ADC development to align with the job requirements.
Craft a Compelling Cover Letter: Write a cover letter that showcases your passion for cancer treatment innovation and your understanding of the '5 Rs' framework. Use specific examples from your past experiences to demonstrate how you can contribute to the company's mission.
Proofread and Edit: Before submitting your application, carefully proofread your CV and cover letter for any grammatical errors or typos. A polished application reflects your attention to detail and professionalism, which is crucial for a leadership role.
How to prepare for a job interview at Apsida Life Science
✨Understand the 5 Rs Framework
Familiarise yourself with the '5 Rs' framework that the company uses for their multispecific ADC programmes. Be prepared to discuss how your experience aligns with these principles and how you can contribute to developing effective translational science strategies.
✨Showcase Your Technical Expertise
Highlight your background in PK/PD modelling, biomarker strategy, and mechanism of action studies. Be ready to provide specific examples from your past work that demonstrate your ability to guide preclinical development and IND readiness.
✨Engage with Industry Knowledge
Research the latest trends and advancements in ADC technology and oncology. Being able to discuss recent developments or challenges in the field will show your passion and commitment to the role, making you a more attractive candidate.
✨Prepare for Collaborative Discussions
Since the role involves collaboration with external consultants and KOLs, think about your previous experiences working in teams. Prepare to share examples of how you've successfully collaborated on protocol development or clinical site strategies in the past.
