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- Tasks: Join a dynamic team to optimise CHO cell lines for therapeutic molecule expression.
- Company: Be part of an innovative company driving advancements in immunotherapeutic manufacturing.
- Benefits: Enjoy a competitive salary, comprehensive benefits, and a supportive work environment.
- Why this job: Make a real impact in therapeutic development while working with cutting-edge technologies.
- Qualifications: Degree in biological sciences and hands-on experience with suspension cell cultures required.
- Other info: On-site role in a state-of-the-art laboratory located in Oxford.
The predicted salary is between 28800 - 48000 £ per year.
We’re hiring an Associate Scientist to join a dynamic target discovery team focused on optimizing CHO cell lines for therapeutic molecule expression. This is an exciting opportunity to contribute to the development of next-generation mammalian expression systems and help drive innovation in immunotherapeutic manufacturing.
About the Role
In this hands-on lab-based role, you'll execute and improve target discovery pipelines to identify and validate genetic targets that enhance cell line productivity and critical quality attributes. Working as part of a collaborative, multidisciplinary team, you'll design and conduct small-scale cell culture experiments using high-throughput technologies and support the development of more efficient bioprocesses.
Key Responsibilities
- Design, plan, and execute CHO cell culture experiments using automated, small-scale models.
- Perform molecular biology assays (e.g., flow cytometry, qRT-PCR, Western blotting, ELISA).
- Contribute to CRISPR/Cas9 knockout and ORF library screening projects.
- Maintain accurate documentation and ensure high standards of data integrity.
- Draft SOPs, training guides, and safety documentation.
- Mentor and train colleagues in laboratory techniques and best practices.
- Support lab maintenance and contribute to health and safety compliance.
What We’re Looking For
- Degree in a relevant biological science field (BSc, MSc, or PhD).
- Strong hands-on experience with suspension cell cultures, ideally CHO cells.
- Proficiency in single-cell cloning, transfections, and molecular assays.
- Skilled in experimental planning, data analysis, and troubleshooting.
- Strong communication skills and ability to work collaboratively in a fast-paced environment.
Desirable Extras
- Experience with BD FACSAria Fusion, lentiviral systems, or high-throughput platforms like Beacon or Ambr15.
- Background in antibody production and overexpression library design.
Salary & Benefits
- Competitive salary
- Comprehensive benefits package
- Supportive, innovation-driven work environment
- Opportunities for professional development
Location
On-site role in a state-of-the-art laboratory - Oxford
Ready to Make an Impact?
If you’re motivated by science and innovation and want to be part of a team making a real difference in therapeutic development, we’d love to hear from you. Apply today and help shape the future of bioprocessing.
Research Associate employer: Cranleigh STEM, Sustainability & SHEQ Recruitment
Contact Detail:
Cranleigh STEM, Sustainability & SHEQ Recruitment Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Research Associate
✨Tip Number 1
Familiarise yourself with the latest advancements in CHO cell line optimisation and therapeutic molecule expression. This knowledge will not only help you during interviews but also demonstrate your genuine interest in the role and the field.
✨Tip Number 2
Network with professionals in the bioprocessing and cell culture fields. Attend relevant conferences or webinars, and connect with current or former employees of StudySmarter on platforms like LinkedIn to gain insights into the company culture and expectations.
✨Tip Number 3
Prepare to discuss specific techniques and technologies mentioned in the job description, such as CRISPR/Cas9 and high-throughput platforms. Being able to articulate your hands-on experience with these methods will set you apart from other candidates.
✨Tip Number 4
Showcase your collaborative skills by preparing examples of past teamwork experiences. Highlight how you contributed to a project’s success, especially in a fast-paced lab environment, as this aligns with the role's emphasis on collaboration.
We think you need these skills to ace Research Associate
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in biological sciences, particularly with CHO cell cultures and molecular biology assays. Use specific examples to demonstrate your hands-on skills and any projects you've worked on that align with the job description.
Craft a Compelling Cover Letter: In your cover letter, express your passion for scientific innovation and how your background makes you a perfect fit for the role. Mention specific experiences that relate to the responsibilities listed, such as designing experiments or mentoring colleagues.
Highlight Relevant Skills: Clearly outline your proficiency in techniques mentioned in the job description, like flow cytometry, qRT-PCR, and CRISPR/Cas9. Use bullet points to make these skills stand out and ensure they are easy to find.
Showcase Team Collaboration: Since the role involves working in a multidisciplinary team, include examples of past collaborative projects. Highlight your communication skills and ability to work in fast-paced environments, as these are key attributes the company is looking for.
How to prepare for a job interview at Cranleigh STEM, Sustainability & SHEQ Recruitment
✨Showcase Your Technical Skills
Be prepared to discuss your hands-on experience with CHO cell cultures and molecular biology assays. Highlight specific projects where you've successfully executed experiments, as this will demonstrate your practical knowledge and ability to contribute to the team.
✨Demonstrate Collaborative Spirit
Since the role involves working in a multidisciplinary team, share examples of how you've collaborated with others in past projects. Emphasise your communication skills and how you can effectively work in a fast-paced environment.
✨Prepare for Problem-Solving Questions
Expect questions that assess your troubleshooting abilities. Think of scenarios where you've encountered challenges in experimental planning or data analysis, and be ready to explain how you resolved them.
✨Familiarise Yourself with Current Technologies
Research the latest high-throughput technologies and platforms mentioned in the job description, such as BD FACSAria Fusion or Beacon. Showing that you're up-to-date with industry advancements will reflect your commitment to innovation and continuous learning.
