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- Tasks: Join a team to optimise CHO cell lines for therapeutic molecule expression in a hands-on lab role.
- Company: Be part of a dynamic company driving innovation in immunotherapeutic manufacturing.
- Benefits: Enjoy a competitive salary, comprehensive benefits, and opportunities for professional development.
- Why this job: Make a real impact in therapeutic development while working in a supportive, innovation-driven environment.
- Qualifications: Degree in biological sciences with hands-on experience in suspension cell cultures and molecular assays.
- Other info: This is an on-site role in a state-of-the-art laboratory located in Oxford.
The predicted salary is between 28800 - 48000 £ per year.
We’re hiring an Associate Scientist to join a dynamic target discovery team focused on optimizing CHO cell lines for therapeutic molecule expression. This is an exciting opportunity to contribute to the development of next-generation mammalian expression systems and help drive innovation in immunotherapeutic manufacturing.
About the Role
In this hands-on lab-based role, you'll execute and improve target discovery pipelines to identify and validate genetic targets that enhance cell line productivity and critical quality attributes. Working as part of a collaborative, multidisciplinary team, you'll design and conduct small-scale cell culture experiments using high-throughput technologies and support the development of more efficient bioprocesses.
Key Responsibilities
- Design, plan, and execute CHO cell culture experiments using automated, small-scale models.
- Perform molecular biology assays (e.g., flow cytometry, qRT-PCR, Western blotting, ELISA).
- Contribute to CRISPR/Cas9 knockout and ORF library screening projects.
- Maintain accurate documentation and ensure high standards of data integrity.
- Draft SOPs, training guides, and safety documentation.
- Mentor and train colleagues in laboratory techniques and best practices.
- Support lab maintenance and contribute to health and safety compliance.
What We’re Looking For
- Degree in a relevant biological science field (BSc, MSc, or PhD).
- Strong hands-on experience with suspension cell cultures, ideally CHO cells.
- Proficiency in single-cell cloning, transfections, and molecular assays.
- Skilled in experimental planning, data analysis, and troubleshooting.
- Strong communication skills and ability to work collaboratively in a fast-paced environment.
Desirable Extras
- Experience with BD FACSAria Fusion, lentiviral systems, or high-throughput platforms like Beacon or Ambr15.
- Background in antibody production and overexpression library design.
Salary & Benefits
- Competitive salary
- Comprehensive benefits package
- Supportive, innovation-driven work environment
- Opportunities for professional development
Location
On-site role in a state-of-the-art laboratory - Oxford
Ready to Make an Impact?
If you’re motivated by science and innovation and want to be part of a team making a real difference in therapeutic development, we’d love to hear from you. Apply today and help shape the future of bioprocessing.
Research Associate: Cell Line Development employer: Cranleigh Scientific
Contact Detail:
Cranleigh Scientific Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Research Associate: Cell Line Development
✨Tip Number 1
Familiarise yourself with the latest advancements in CHO cell line development and bioprocessing. Being knowledgeable about current trends and technologies will help you stand out during discussions with our team.
✨Tip Number 2
Network with professionals in the field by attending relevant conferences or workshops. This can provide you with valuable insights and connections that may enhance your application and show your commitment to the industry.
✨Tip Number 3
Prepare to discuss your hands-on experience with molecular biology assays and cell culture techniques in detail. Be ready to share specific examples of your work and how it relates to the responsibilities outlined in the job description.
✨Tip Number 4
Demonstrate your collaborative skills by highlighting any previous experiences where you worked in multidisciplinary teams. Emphasising your ability to communicate effectively and mentor others will resonate well with our team-oriented culture.
We think you need these skills to ace Research Associate: Cell Line Development
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in cell line development, particularly with CHO cells. Include specific examples of your hands-on lab work and any molecular biology assays you've performed.
Craft a Compelling Cover Letter: Write a cover letter that showcases your passion for scientific innovation and your understanding of the role. Mention how your skills align with the responsibilities listed, such as designing CHO cell culture experiments and contributing to CRISPR/Cas9 projects.
Highlight Collaborative Experience: Since the role involves working in a multidisciplinary team, emphasise any previous collaborative projects. Discuss how you contributed to team success and your ability to communicate effectively in a fast-paced environment.
Showcase Continuous Learning: Mention any additional training or certifications related to bioprocessing or molecular biology. This could include workshops, online courses, or relevant research projects that demonstrate your commitment to professional development.
How to prepare for a job interview at Cranleigh Scientific
✨Showcase Your Hands-On Experience
Be prepared to discuss your practical experience with CHO cell cultures and molecular biology assays. Highlight specific projects where you successfully executed experiments, as this will demonstrate your capability in a lab-based role.
✨Demonstrate Problem-Solving Skills
Expect questions that assess your troubleshooting abilities. Share examples of challenges you've faced in experimental planning or data analysis, and explain how you resolved them. This shows your analytical thinking and adaptability.
✨Emphasise Team Collaboration
Since the role involves working in a multidisciplinary team, be ready to discuss your experiences collaborating with others. Mention any mentoring roles you've taken on, as well as how you contribute to a positive team environment.
✨Prepare for Technical Questions
Brush up on your knowledge of techniques like CRISPR/Cas9 and high-throughput technologies. Be ready to answer technical questions or even solve hypothetical scenarios related to these methods, showcasing your expertise and confidence.
