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- Tasks: Lead the analysis of antibody sequence data to discover novel therapeutic antibodies.
- Company: Alchemab Therapeutics is innovating antibody drug discovery using cutting-edge bioinformatics.
- Benefits: Enjoy a full-time role with opportunities for remote work and professional growth.
- Why this job: Join a passionate team dedicated to transforming patient therapies through innovative research.
- Qualifications: PhD in Bioinformatics or Immunology with significant industry experience required.
- Other info: Collaborate across disciplines and contribute to strategic planning in a fast-paced environment.
The predicted salary is between 43200 - 72000 £ per year.
We are seeking a talented and creative Bioinformatician with a passion for using computational advances to improve every step of the antibody drug discovery process. This will involve leading the analysis of high-throughput antibody sequence data and antigen proteomics data to uncover novel therapeutic antibodies and disease pathways. Once candidates are identified, data-driven target validation, and translational bioinformatics will be applied to progress these antibodies towards the clinic. The role will also involve platform development to ensure we innovate and incorporate technological advances. The Principal Bioinformatician is a team player who can work across multiple areas in the company, delivering computational and biological expertise, technical rigour, and an inquisitive mindset to discover the best therapies for patients.
Responsibilities
- Discovering novel antibodies and therapeutic targets through analysis of antibody and antigen sequence datasets.
- Validating emerging targets using multi-omics datasets and data-driven target validation techniques.
- Contributing to experimental design, and performing data analysis to help elucidate the biological function of our antibody drug candidates.
- Building strong scientific cases around your findings, and presenting these to the wider company to inform strategic decisions.
- Contribution to platform development through exploratory research and methods development.
- Leading new projects and engaging in long-term strategic planning.
- Keeping current on new discoveries, methodologies and approaches that might enhance Alchemab’s platform.
A PhD (or equivalent experience) in Immunology, Bioinformatics, or similar discipline, and significant antibody drug discovery industry experience. Mastery in integrating and analysing omics data sets (including immune repertoire) and deriving biological insight from them. Evidence of contribution to and influence of scientific strategy. Demonstrated leadership skills to guide a team of bioinformaticians and collaborate effectively with biologists, clinicians, and other stakeholders on interdisciplinary projects. Ability to effectively adapt and prioritise workloads in a fast-changing environment. Self-motivated, with ability and desire to take ownership of core bioinformatic operations. An ambition to work with the Alchemab team to build a transformative company. Experience in the development and application of machine learning models. Experience in a range of statistical analysis techniques. Experience in antibody or protein structural modelling and antibody structure-function relationship.
NOTE: This job description is not intended to be all inclusive. Employees may perform other related duties as negotiated to meet the ongoing needs of the organisation.
Principal Bioinformatician employer: Alchemab Therapeutics Ltd
Contact Detail:
Alchemab Therapeutics Ltd Recruiting Team
hr@alchemab.com
StudySmarter Expert Advice 🤫
We think this is how you could land Principal Bioinformatician
✨Tip Number 1
Network with professionals in the bioinformatics and antibody drug discovery fields. Attend relevant conferences, webinars, or workshops to meet potential colleagues and learn about the latest trends and technologies. This can help you gain insights into what Alchemab Therapeutics is looking for in a candidate.
✨Tip Number 2
Familiarise yourself with the specific tools and technologies mentioned in the job description, such as machine learning models and statistical analysis techniques. Being able to discuss your experience with these tools during an interview will demonstrate your readiness for the role.
✨Tip Number 3
Prepare to showcase your leadership skills and collaborative experiences. Think of examples where you've successfully led projects or worked with interdisciplinary teams, as this is crucial for the Principal Bioinformatician role at Alchemab.
✨Tip Number 4
Stay updated on recent advancements in bioinformatics and antibody drug discovery. Being knowledgeable about current research and methodologies will not only help you in interviews but also show your genuine interest in contributing to Alchemab's mission.
We think you need these skills to ace Principal Bioinformatician
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in bioinformatics, particularly in antibody drug discovery. Emphasise your skills in integrating and analysing omics datasets, as well as any leadership roles you've held.
Craft a Compelling Cover Letter: In your cover letter, express your passion for computational biology and how it aligns with Alchemab's mission. Mention specific projects or experiences that demonstrate your ability to lead and innovate in the field.
Showcase Technical Skills: Clearly outline your technical skills related to machine learning models, statistical analysis techniques, and antibody structure-function relationships. Provide examples of how you've applied these skills in previous roles.
Highlight Collaborative Experience: Since the role requires working across multiple areas, include examples of successful collaborations with biologists, clinicians, or other stakeholders. This will show your ability to work effectively in interdisciplinary teams.
How to prepare for a job interview at Alchemab Therapeutics Ltd
✨Showcase Your Technical Expertise
Be prepared to discuss your experience with integrating and analysing omics datasets. Highlight specific projects where you derived biological insights from complex data, as this will demonstrate your mastery in the field.
✨Demonstrate Leadership Skills
Since the role involves guiding a team of bioinformaticians, be ready to share examples of how you've led projects or collaborated with interdisciplinary teams. This will show that you can effectively manage and inspire others.
✨Stay Current with Industry Trends
Research recent advancements in antibody drug discovery and bioinformatics methodologies. Being able to discuss these trends during your interview will illustrate your commitment to continuous learning and innovation.
✨Prepare for Problem-Solving Questions
Expect questions that assess your ability to adapt and prioritise in a fast-changing environment. Think of scenarios where you've successfully navigated challenges and be ready to explain your thought process.
