At a Glance
- Tasks: Develop and implement computational methods for analysing biological data in gene therapy.
- Company: Asklepios BioPharmaceutical is a pioneering gene therapy company focused on life-saving medicines.
- Benefits: Enjoy a collaborative environment, mentorship opportunities, and the chance to work on groundbreaking science.
- Why this job: Join a mission-driven team transforming lives through innovative science and cutting-edge technology.
- Qualifications: PhD or Master's in bioinformatics with relevant experience; strong programming skills in Python required.
- Other info: This is an on-site position in Edinburgh, offering a unique opportunity to contribute to global research.
The predicted salary is between 36000 - 60000 £ per year.
Asklepios BioPharmaceutical, Inc. (AskBio) is a leading, clinical-stage gene therapy company founded in 2001 based on the work of adeno-associated virus (AAV) gene therapy visionary and pioneer, Jude Samulski, PhD. Our commitment to developing life-saving medicines that can potentially cure genetic diseases has never wavered. At AskBio, we have built a foundation of therapeutic programs, AAV manufacturing and a rich portfolio of patented technology. Our therapeutic focus includes neuromuscular, central nervous system, cardiovascular and metabolic diseases with clinical trials underway for Pompe disease, Parkinson's disease, and congestive heart failure.
Our gene therapy platform includes Pro10, an industry-leading proprietary cell line manufacturing process, and an extensive AAV capsid and promoter library. We became a wholly-owned, independently operated, subsidiary of Bayer AG in late 2020 as a cornerstone of its newly formed Cell & Gene Therapy (CGT) platform. Our global headquarters is in Research Triangle Park, NC. Additionally, we have significant operations in Philadelphia, PA, Columbus, OH, Scotland, France, Germany, and Spain.
Position Summary
The Scientist II, Bioinformatics develops and implements computational methods for analysing proprietary biological data, supporting cross-functional teams with tailored bioinformatics solutions. Will have expertise in omics data analysis, statistical methods, and scientific programming. The role contributes to innovative computational research in gene therapy, advancing AskBio's platform-enabled product approach. This is an on-site based position in UK Edinburgh reporting to the Sr. Director, Bioinformatics and Machine Learning.
Job Responsibilities
- Develop and implement computational methods and algorithms for the analysis of proprietary biological data
- Collaborate with cross-functional international teams to understand data analysis needs and provide tailored bioinformatics solutions
- Contribute to the design and optimisation of bioinformatics pipelines and workflows to improve data processing and analysis
- Stay up to date with advancements in bioinformatics, machine learning, and data science, integrating relevant approaches into ongoing work
- Communicate findings and recommendations effectively to stakeholders, including senior leadership and non-expert audiences
- Provide mentorship and guidance to junior team members, fostering a culture of collaboration and learning
Minimum Requirements
- PhD in bioinformatics, computational biology, or a related discipline with at least 2+ years of postdoctoral or relevant industry experience; or Master's degree in bioinformatics, computational biology, or a related field with at least 8 years of relevant industry or research experience
- Strong programming skills in Python
- Experience in statistical analysis of DNA sequence and molecular datasets
- Proven ability to communicate complex computational analyses to both technical and non-technical audience
- Expertise in processing and analyzing omic datasets, particularly next-generation sequencing (NGS) data
- Familiarity with Unix/Linux-based systems and command-line environments
Preferred Skills & Abilities
- Experience developing computational methods for biological data analysis
- Experience working with clinical or translational research data
- Proficiency in additional data analysis languages (e.g., R, MATLAB)
- Knowledge of containerization tools such as Docker
- Familiarity with integrating multi-omics datasets
- Experience with workflow management systems such as Snakemake or Nextflow
- Knowledge of gene therapy and its bioinformatics challenges
- Expertise in structural biology, particularly in protein structure modelling, interactions, and computational structural analysis
- Experience contributing to cross-disciplinary and global research projects
- Familiarity with version control systems (e.g., Git) and collaborative development practices
Asklepios BioPharmaceutical, Inc.: Scientist II, Bioinformatics employer: Lisebleijs
Contact Detail:
Lisebleijs Recruiting Team
careers@askbio.com
StudySmarter Expert Advice 🤫
We think this is how you could land Asklepios BioPharmaceutical, Inc.: Scientist II, Bioinformatics
✨Tip Number 1
Familiarise yourself with the latest advancements in bioinformatics and gene therapy. This will not only help you understand the role better but also allow you to engage in meaningful conversations during interviews, showcasing your passion and knowledge.
✨Tip Number 2
Network with professionals in the bioinformatics field, especially those who have experience in gene therapy. Attend relevant conferences or webinars, and connect with them on platforms like LinkedIn to gain insights and potentially get referrals.
✨Tip Number 3
Prepare to discuss specific projects where you've developed computational methods for biological data analysis. Be ready to explain your thought process, the challenges you faced, and how you overcame them, as this will demonstrate your problem-solving skills.
✨Tip Number 4
Showcase your programming skills by contributing to open-source bioinformatics projects or creating your own. This not only enhances your portfolio but also demonstrates your commitment to continuous learning and collaboration in the field.
We think you need these skills to ace Asklepios BioPharmaceutical, Inc.: Scientist II, Bioinformatics
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in bioinformatics, computational biology, and any specific programming skills mentioned in the job description, such as Python. Use keywords from the job listing to ensure your application stands out.
Craft a Compelling Cover Letter: Write a cover letter that not only outlines your qualifications but also demonstrates your passion for gene therapy and how your background aligns with AskBio's mission. Mention specific projects or experiences that relate to the role.
Showcase Your Technical Skills: In your application, provide examples of your experience with statistical analysis, omics data processing, and any relevant programming languages. Highlight any familiarity with tools like Docker or workflow management systems, as these are preferred skills.
Prepare for Communication: Since the role requires communicating complex analyses to both technical and non-technical audiences, consider including examples of how you've successfully communicated findings in past roles. This will demonstrate your ability to bridge the gap between science and stakeholders.
How to prepare for a job interview at Lisebleijs
✨Showcase Your Technical Skills
Make sure to highlight your programming skills, especially in Python, and any experience you have with statistical analysis of DNA sequences. Be prepared to discuss specific projects where you've applied these skills.
✨Understand the Company’s Mission
Familiarise yourself with AskBio's vision and mission. Be ready to explain how your background and values align with their commitment to pioneering science and transforming lives through gene therapy.
✨Prepare for Collaborative Questions
Since the role involves working with cross-functional teams, think of examples that demonstrate your ability to collaborate effectively. Be ready to discuss how you’ve communicated complex analyses to both technical and non-technical audiences.
✨Stay Updated on Bioinformatics Trends
Research recent advancements in bioinformatics and machine learning. Being able to discuss current trends and how they could apply to AskBio's work will show your enthusiasm and commitment to the field.