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- Tasks: Support R&D in molecular biology, cell culture, and protein purification in a lab setting.
- Company: Join LGC, a leader in diagnostics and genomics, making a real impact in life sciences.
- Benefits: Enjoy a collaborative environment, opportunities for growth, and the chance to contribute to meaningful research.
- Why this job: Be part of innovative projects that enhance healthcare and diagnostics while working with cutting-edge technology.
- Qualifications: A background in biology or related fields; lab experience is a plus but not mandatory.
- Other info: Work in an ISO 9001-accredited facility in Oxford, surrounded by passionate professionals.
The predicted salary is between 30000 - 50000 £ per year.
Department: Scientific / Technical Science
Company Description: LGC's Diagnostics and Genomics Business Unit encompasses a wide range of operating entities focused on the development and manufacture of diagnostic quality solutions and component materials for the extended life sciences industry. We partner with in vitro diagnostics (IVD) assay developers and pharmaceutical, CRO, and academic institutions, in commercialisation activities across the entire diagnostic pipeline - from concept and early-stage research, through expedited product development, and onwards into routine clinical use. Lab-based and diagnostic professionals across disciplines including clinical chemistry, immunochemistry, serology, molecular diagnostics, and clinical genomics rely on LGC's products to support accurate and reliable results.
The Native Antigen Company (TNAC) sits within LGC's Diagnostics and Genomics Business Unit and operates an ISO 9001-accredited facility in Oxford, UK. TNAC is a manufacturer and supplier of antigens and antibodies that form key components in vaccine research and in the accurate diagnosis of a wide range of infectious and non-infectious diseases. Our customer base includes key pharmaceutical and IVD companies, the academic sector, and a diverse range of biotechnology companies.
Job Description: The role of Scientist I/II (Upstream) is to support TNAC's R&D function by following SOPs, as directed by senior staff in areas such as molecular biology, cell culture, and protein purification. The role will be mainly lab-based.
- Key roles and responsibilities include, but are not limited to:
- Working proficiently and independently to existing SOPs in the following fields:
- Molecular Biology: Construction of expression vectors using standard techniques such as RNA and DNA extraction; preparative and analytical PCR; reverse-transcription PCR; restriction digestion; agarose electrophoresis; Gibson assembly; preparation of transfection-grade plasmids at various scales; Sanger and Nanopore sequencing.
- Bacterial cell culture: Preparation of growth media; transformation of bacteria; expression testing and optimisation of culture conditions; native and recombinant protein expression at various scales; harvesting and QC testing of raw materials.
- Mammalian cell culture: Maintenance of cell lines; performing small- and large-scale transfections; harvesting and QC testing of raw materials.
- Protein purification and analysis: Preparation of suitable buffers; small-scale FPLC purification of target proteins using spin columns; SDS-PAGE; Western blotting; and ELISA.
- Day-to-day reporting of results to line manager(s), as required.
- Helping with ordering and maintaining stock levels of high-turnover items and reagents.
- Weekly supervisor meetings.
- Attendance and presentation at weekly lab meetings.
- Developing an ability to understand and convey relevant published research.
- Additional duties, as required by senior R&D staff.
The Scientist I/II (Upstream) will also be able to demonstrate the following traits in line with LGC's Core Values:
- Passion: Pride in our achievements engenders passion for our work and translates into our shared ambition to make the world a safer place.
- Curiosity: We constantly look forward to what's next: our curiosity for today's discoveries makes tomorrow's innovations possible.
- Integrity: A commitment to high ethical standards has been at the heart of LGC since we first started testing the integrity of products in 1842.
- Brilliance: We strive to be the very best in everything we say and do. We exceed customers' expectations through innovation and pioneering science.
- Respect: We respect gender, age, nationality, religion, and individuality - our diversity is our strength.
Scientist I/II (Upstream) employer: LGC
Contact Detail:
LGC Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Scientist I/II (Upstream)
✨Tip Number 1
Familiarise yourself with the specific techniques mentioned in the job description, such as molecular biology methods and protein purification. Being able to discuss these techniques confidently during an interview will show your preparedness and enthusiasm for the role.
✨Tip Number 2
Network with professionals in the diagnostics and genomics field, especially those who work at LGC or similar companies. Engaging with them on platforms like LinkedIn can provide insights into the company culture and may even lead to referrals.
✨Tip Number 3
Prepare to demonstrate your understanding of LGC's core values during the interview. Think of examples from your past experiences that showcase your passion, curiosity, integrity, brilliance, and respect, as these traits are essential for the role.
✨Tip Number 4
Stay updated on the latest research and developments in the field of diagnostics and genomics. Being knowledgeable about current trends and breakthroughs can help you engage in meaningful discussions during interviews and show your commitment to the industry.
We think you need these skills to ace Scientist I/II (Upstream)
Some tips for your application 🫡
Understand the Role: Before applying, make sure you fully understand the responsibilities and requirements of the Scientist I/II (Upstream) position. Familiarise yourself with the specific techniques mentioned in the job description, such as molecular biology, cell culture, and protein purification.
Tailor Your CV: Customise your CV to highlight relevant experience and skills that align with the job description. Emphasise your lab-based experience, particularly in molecular biology and cell culture, and include any specific techniques you have mastered.
Craft a Compelling Cover Letter: Write a cover letter that showcases your passion for scientific research and your curiosity about innovations in the field. Mention how your values align with LGC's core values, such as integrity and respect, and provide examples of your achievements in previous roles.
Proofread Your Application: Before submitting your application, carefully proofread all documents for spelling and grammatical errors. Ensure that your application is clear, concise, and professional, as attention to detail is crucial in scientific roles.
How to prepare for a job interview at LGC
✨Know Your SOPs
Familiarise yourself with the standard operating procedures (SOPs) relevant to molecular biology, cell culture, and protein purification. Be prepared to discuss how you have followed these in past experiences or how you would approach them in this role.
✨Demonstrate Your Technical Skills
Be ready to talk about specific techniques you've used, such as PCR, cell culture, or protein purification methods. Highlight any hands-on experience you have and be prepared to explain your process and results.
✨Showcase Your Passion and Curiosity
LGC values passion and curiosity. Share examples of how your enthusiasm for scientific discovery has driven your work. Discuss any recent research that excites you and how it relates to the role you're applying for.
✨Emphasise Teamwork and Communication
Since the role involves reporting results and attending lab meetings, highlight your ability to work collaboratively. Provide examples of how you've effectively communicated findings to colleagues or contributed to team projects in the past.
