Senior/Principal Bioinformatician
Senior/Principal Bioinformatician

Senior/Principal Bioinformatician

London Full-Time 43200 - 72000 £ / year (est.) Home office (partial)
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At a Glance

  • Tasks: Lead bioinformatic analyses for drug discovery and collaborate across teams.
  • Company: Hlx Life Sciences is pioneering innovative solutions in biotechnology and pharmaceuticals.
  • Benefits: Enjoy a hybrid work model with flexible hours and opportunities for professional growth.
  • Why this job: Join a dynamic team making impactful contributions to drug discovery and patient care.
  • Qualifications: PhD in bioinformatics or related field, with experience in cancer biology and programming skills.
  • Other info: This role requires 3 days on-site per week, fostering collaboration and innovation.

The predicted salary is between 43200 - 72000 £ per year.

We are looking for a driven and experienced Senior or Principal Bioinformatician to lead the design and execution of bioinformatic analyses that support a variety of drug discovery initiatives. The role involves leveraging both public and proprietary large-scale patient, genomic, and functional datasets to guide and inform the company’s drug discovery priorities.

Key Responsibilities

  • Provide innovative solutions to complex biological problems to gain new insights into multiple aspects of drug discovery.
  • Collaborate with colleagues across the company to translate business needs into high value analysis in a timely fashion.
  • Work as a team to exploit and expand the data science infrastructure to meet business needs in a rapidly evolving environment.
  • Expand and maintain internal bioinformatic tools.
  • Work to achieve scientific deliverables and milestones at agreed quality and timescales.
  • Identify and mitigate risks as they emerge.
  • Establish appropriate communication with line manager, project team members and other stakeholders to ensure they are kept informed of workloads, issues, progress, results, innovation and developments.
  • Actively demonstrate best practice and behaviours to create a positive, productive and inclusive working environment.
  • Communicate analytical products and outputs to stakeholders.
  • Seek input and feedback from internal and external stakeholders about their requirements and prioritize your workload.
  • Interact with the Leadership team, project teams and external collaborators to aid in the delivery of projects.
  • Contribute to the general duties of the company and pass on skills and knowledge to other team members.

Skills Required

  • A PhD in bioinformatics, pharmacology, molecular biology or related scientific discipline and/or experience in bioinformatics gained in academia or industry (E)
  • Knowledge of cancer biology, cancer genomics, or cancer therapeutics (E)
  • Experience of using bioinformatics tools to guide drug development in areas such as biomarker identification, patient selection, mechanisms of action and resistance (E)
  • A track record of developing analytical solutions to complex biological problems (E)
  • Advanced knowledge of programming in Python or similar (E)
  • Experience in the integration, analysis and functional interpretation of omics experiments/datasets (transcriptomics, proteomics, CRISPR) (E)
  • Experience using statistical testing, including hypothesis testing and power analysis (E)
  • Desirable for Senior Role, Essential for Principal Role: Experience in the analysis of large-scale genomic and functional genomic datasets through the use of automated workflows (D/E)
  • Experience in analysis of clinical data analysis (D/E)
  • Experience with cloud computing and software containerization (D)
  • Knowledge of current software development methodologies e.g. Scrum/Agile, CI/CD, Concurrent Version Systems (e.g. Git) (D)
  • Previous experience developing, deploying and maintaining software tools (D/E)
  • Previous experience of developing, deploying and/or maintaining web user interfaces and/or REST APIs (D)

This is a hybrid role that requires 3 days on-site per week.

Senior/Principal Bioinformatician employer: Hlx Life Sciences

Hlx Life Sciences is an exceptional employer located in the vibrant city of Cambridge, offering a dynamic work culture that fosters innovation and collaboration. Employees benefit from a supportive environment that prioritises professional growth, with opportunities to lead cutting-edge bioinformatic analyses in drug discovery while working alongside industry experts. The hybrid work model allows for flexibility, ensuring a healthy work-life balance while contributing to meaningful scientific advancements.
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Contact Detail:

Hlx Life Sciences Recruiting Team

StudySmarter Expert Advice 🤫

We think this is how you could land Senior/Principal Bioinformatician

✨Tip Number 1

Network with professionals in the bioinformatics field, especially those who work in drug discovery. Attend relevant conferences or webinars to meet potential colleagues and learn about the latest trends and technologies that could be beneficial for your role.

✨Tip Number 2

Familiarise yourself with the specific bioinformatics tools and programming languages mentioned in the job description, such as Python. Consider working on personal projects or contributing to open-source initiatives to showcase your skills and experience.

✨Tip Number 3

Prepare to discuss your previous experiences in developing analytical solutions for complex biological problems. Be ready to provide examples of how you've successfully collaborated with cross-functional teams to achieve scientific deliverables.

✨Tip Number 4

Stay updated on the latest advancements in cancer biology and genomics. This knowledge will not only help you during interviews but also demonstrate your genuine interest in the field and the company's mission.

We think you need these skills to ace Senior/Principal Bioinformatician

PhD in bioinformatics, pharmacology, molecular biology or related scientific discipline
Knowledge of cancer biology, cancer genomics, or cancer therapeutics
Experience using bioinformatics tools for drug development
Track record of developing analytical solutions to complex biological problems
Advanced programming skills in Python or similar languages
Integration and analysis of omics datasets (transcriptomics, proteomics, CRISPR)
Statistical testing expertise, including hypothesis testing and power analysis
Experience with large-scale genomic and functional genomic datasets
Clinical data analysis experience
Familiarity with cloud computing and software containerization
Knowledge of software development methodologies (e.g. Scrum/Agile, CI/CD)
Experience developing and maintaining software tools
Experience with web user interfaces and REST APIs
Strong communication skills for stakeholder engagement
Ability to work collaboratively in a team environment
Problem-solving skills to identify and mitigate risks

Some tips for your application 🫡

Tailor Your CV: Make sure your CV highlights relevant experience in bioinformatics, particularly any work related to drug discovery and the analysis of large-scale datasets. Use specific examples that demonstrate your problem-solving skills and technical expertise.

Craft a Compelling Cover Letter: In your cover letter, express your passion for bioinformatics and how your background aligns with the company's goals. Mention specific projects or experiences that showcase your ability to provide innovative solutions to complex biological problems.

Highlight Technical Skills: Clearly outline your programming skills, especially in Python or similar languages, and your experience with bioinformatics tools. Include any knowledge of cloud computing, software development methodologies, and your familiarity with omics datasets.

Showcase Collaboration Experience: Since the role involves collaboration across teams, include examples of how you've successfully worked with others in previous roles. Highlight your communication skills and ability to translate business needs into actionable analyses.

How to prepare for a job interview at Hlx Life Sciences

✨Showcase Your Technical Expertise

Be prepared to discuss your experience with bioinformatics tools and programming languages, especially Python. Highlight specific projects where you've developed analytical solutions to complex biological problems, as this will demonstrate your capability to contribute effectively to drug discovery initiatives.

✨Understand the Company’s Focus

Research Hlx Life Sciences and their current drug discovery projects. Familiarise yourself with their approach to cancer biology and genomics, as well as any recent publications or breakthroughs. This knowledge will help you tailor your responses and show genuine interest in their work.

✨Emphasise Collaboration Skills

Since the role involves working closely with various teams, be ready to provide examples of how you've successfully collaborated in the past. Discuss how you’ve translated business needs into high-value analyses and how you maintain effective communication with stakeholders.

✨Prepare for Problem-Solving Scenarios

Expect to face questions that assess your problem-solving abilities. Prepare to discuss specific challenges you've encountered in bioinformatics and how you approached them. This will showcase your critical thinking skills and your ability to innovate under pressure.

Senior/Principal Bioinformatician
Hlx Life Sciences
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  • Senior/Principal Bioinformatician

    London
    Full-Time
    43200 - 72000 £ / year (est.)

    Application deadline: 2027-06-19

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    Hlx Life Sciences

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